Guideline Central Blog

Upcoming FDA Approvals & Decisions - January 2025

Upcoming FDA Decisions – January 2025

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

British Society for Rheumatology Int'l Guidelines

British Society for Rheumatology (BSR) – Guidelines International Series

In this edition of our Guidelines International Series, we delve into the British Society for Rheumatology (BSR), the foremost specialist medical society in the UK for rheumatology and musculoskeletal professionals dedicated to enhancing the quality of life for children and adults with rheumatic and musculoskeletal diseases. The BSR is well known for its comprehensive collection […]

Alirocumab (Praluent/Regeneron) – Guidelines+ Monographs

In this edition of the Guidelines+ Monographs Series will delve into the medication alirocumab, marketed under the brand name Praluent® from Regeneron. Praluent (alirocumab) is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor indicated to reduce the risk of myocardial infarction, stroke, and unstable angina requiring hospitalization in adults with established cardiovascular disease, as […]

Guidelines Side-By-Side Acute Ischemic Stroke

Comparing Thrombolytics for Acute Ischemic Stroke Guidelines – Guidelines Side-By-Side

In the United States in 2022, stroke accounted for 1 in 6 deaths related to cardiovascular disease, according to the Centers for Disease Control and Prevention (CDC). The incidence rate of stroke experienced a slight decrease from 41.1 per 100,000 in 2021 to 39.5 per 100,000 in 2022. Ischemic strokes make up approximately 87% of […]

Guidelines+ Trials Spotlight - (Tecvayli) for Patients with Newly Diagnosed Multiple Myeloma

Tecvayli Clinical Trial Results for Patients With Newly Diagnosed Multiple Myeloma – Guidelines+ Trials Spotlight

On October 25, 2022, the US Food and Drug Administration (FDA) granted approval for Johnson & Johnson’s Tecvayli® (teclistamab-cqyv) for the treatment of adult patients with relapsed or refractory multiple myeloma. This approval is specifically for patients who have previously received four or more prior lines of therapy, including a proteasome inhibitor, immunomodulatory drug, and […]

Irinotecan Liposome Injection (Onivide/Ipsen) – Guidelines+ Monographs

Our latest edition of the Guidelines+ Monographs Series will delve into the medication irinotecan liposome injection, marketed under the brand name Onivyde®  by Ipsen. Onivyde (irinotecan liposome injection) is a liposomal formulation of the topoisomerase I inhibitor irinotecan used in the treatment of pancreatic adenocarcinoma. Onivyde is indicated in combination with oxaliplatin, fluorouracil and leucovorin, […]

Guidelines+ Trials Spotlight - TROPION-Lung01 Phase III trial

EGFR-Mutated NSCLC (The TROPION-Lung01 Phase III Trial) – Guidelines+ Trials Spotlight

AstraZeneca and Daiichi Sankyo have collaboratively submitted a new Biologics License Application (BLA) for accelerated approval in the United States for datopotamab deruxtecan (Dato-DXd). This application aims to provide treatment for adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated (EGFR) non-small cell lung cancer (NSCLC) who have previously undergone systemic therapies, including […]

ASH 2024 Conference Recap - Bleeding & Clotting Disorders

2024 ASH Annual Meeting and Exposition – Conference Recap on Bleeding & Clotting Disorders

The 66th ASH Annual Meeting and Exposition took place from December 7-10, 2024, in San Diego, California, as well as online. This event is the premier hematology gathering of the year, attracting over 30,000 health professionals, clinicians, researchers, educators, and other industry experts. Attendees can expect a multitude of sessions, thousands of abstracts, and numerous […]

Guidelines Spotlight Diagnosis & Management of Myocarditis

ACC’s Guidance for the Diagnosis & Management of Myocarditis – Guidelines Spotlight

The American College of Cardiology (ACC) has recently released guidance for diagnosing and treating acute myocarditis in adult patients. The 2024 ACC Expert Consensus Decision Pathway (ECDP) on Strategies and Criteria for the Diagnosis and Management of Myocarditis outlines a 5-step care pathway, along with recommendations for resuming strenuous physical activity. Additionally, the guidelines aim […]

Guideline Timeline - Restless Leg Syndrome

Restless Leg Syndrome – Guidelines Timeline

Restless Legs Syndrome (RLS), also known as Willis-Ekbom Disease, primary RLS, and idiopathic RLS, is a neurological disorder characterized by unpleasant sensations in the legs and an irresistible urge to move them. The Centers for Disease Control (CDC) estimates that up to 7-10% of the US population may be affected by RLS, with onset possible […]

Guidelines Spotlight Diabetes Standards of Care (2025)

Diabetes Standards of Care (2025) – Guidelines Spotlight

Welcome to the latest edition of our Guideline Spotlight, where we will explore the valuable insights and key takeaways from the most recent guideline releases. Today, our focus is on the American Diabetes Association’s (ADA) latest edition of their Standards of Care in Diabetes, which was released on December 9, 2024. This edition consolidates all […]

AUA Seeks Peer Reviewers for Upcoming Vasectomy Guideline

The American Urological Association (AUA) is currently seeking feedback and comments on their draft vasectomy guideline. AUA members and other interested parties will have the opportunity to review the draft guideline starting in January 2025, for a period of approximately two weeks. Prior to receiving a copy of the draft guideline, all reviewers must disclose […]

USPSTF’s Cervical Cancer Screening Recommendation is Now Open for Public Comment

The United States Preventive Services Task Force (USPSTF) recently released their draft recommendation statement titled Cervical Cancer: Screening, which was published online on December 10, 2024. This recommendation serves as an update to the previous 2018 guideline. The latest draft remains consistent with the 2018 recommendation but includes a new recommendation. It now suggests that […]

Guidelines+ Trials Spotlight - Metastatic Squamous Cell Carcinoma of the Head & Neck (STELLAR-305)

Metastatic Squamous Cell Carcinoma of the Head and Neck (STELLAR-305) – Guidelines+ Trials Spotlight

One year ago, Exelixis commenced their phase 2/3 pivotal trial to assess the efficacy of zanzalintinib in combination with pembrolizumab compared to pembrolizumab alone in patients with previously untreated PD-L1-positive recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN). Zanzalintinib, an oral drug developed by Exelixis, targets and inhibits receptor tyrosine kinases […]

Baloxavir Marboxil (Xofluza/Genetech) – Guidelines+ Monographs

In recognition of National Influenza Vaccination Week (NIVW), our latest edition of the Guidelines+ Monographs Series will delve into the medication baloxavir marboxil, marketed under the brand name Xofluza®  by Genentech. Xofluza is an influenza virus polymerase acidic (PA) endonuclease inhibitor indicated for the treatment of acute uncomplicated influenza in patients 5 years of age […]

Guidelines + Trials Rundown Thalassemia

Thalassemia in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on thalassemia in adults. The following list has been carefully curated by evaluating the ongoing phase 3 trials for thalassemia, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This compilation primarily […]

Guidelines + Trials Rundown Ulcerative Colitis

Ulcerative Colitis in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on ulcerative colitis in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for moderately to severe ulcerative colitis, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject […]

CDC’s HIV Screening Guideline is Now Open for Public Comment

The US Centers for Disease Control and Prevention (CDC) has released the latest draft of the Recommendations for HIV Screening in Clinical Settings for public comment. This guideline aims to aid healthcare providers in diagnosing and connecting patients with undiagnosed HIV to clinical care, reestablishing individuals with previously diagnosed HIV in care, detecting HIV infection […]

Guidelines + Trials Rundown Crohn’s Disease

Crohn’s Disease in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on Crohn’s disease in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for Crohn’s disease, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This […]

Guideline Timeline - Influenza Vaccine Recommendations

Influenza Vaccine Recommendations – Guidelines Timeline (National Influenza Vaccination Week)

National Influenza Vaccination Week (NIVW) is a national awareness week dedicated to emphasizing the significance of influenza vaccination. Taking place from December 2-6, 2024, National Influenza Vaccination Week 2024 serves as a timely reminder for individuals aged 6 months and older that there is still an opportunity to receive a flu vaccine this season. Given […]

Guidelines Spotlight HIVAIDS

Human Immunodeficiency Virus (HIV) Guidelines Spotlight – (World AIDS Day)

World AIDS Day is observed annually on December 1st, providing a global platform for individuals to come together in solidarity with those affected by HIV and to honor those who have succumbed to AIDS-related illnesses. Each year, World AIDS Day centers around a specific theme, with this year’s focus being on “Taking the Rights Path.” […]

Bictegravir, Emtricitabine, and Tenofovir Alafenamide (Biktarvy/Gilead ) – Guidelines+ Monographs

In recognition of World AIDS Day 2024, our latest edition of the Guidelines+ Monographs Series will delve into the medication bictegravir, emtricitabine, and tenofovir alafenamide, marketed under the brand name Biktarvy®  by Gilead Sciences, Inc. Biktarvy is a three-drug combination of bictegravir (BIC), a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI), […]

Guidelines Spotlight Management of Central Airway Obstruction

Management of Central Airway Obstruction – Guidelines Spotlight  (COPD Awareness Month)

Welcome to this edition of our Guideline Spotlight, where we will delve into the important insights and key takeaways from the comprehensive guideline on the Management of Central Airway Obstruction, developed by The American College of Chest Physicians (CHEST). Central airway obstruction (CAO) is a critical condition that poses a significant threat to life, leading […]

Upcoming FDA Approvals & Decisions - December 2024

Upcoming FDA Decisions – December 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines Side-By-Side COPD

Comparing the Management of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations Guidelines – Guidelines Side-By-Side

The chronic and progressive nature of chronic obstructive pulmonary disease (COPD) is frequently marked by exacerbations, which are clinically defined as episodes of worsening respiratory symptoms such as dyspnea, cough, increased sputum production, and heightened sputum purulence. These exacerbations not only diminish the quality of life for individuals with COPD but also hasten disease advancement, […]

ASH 2024 Conference Preview - Bleeding & Clotting Disorders

2024 ASH Annual Meeting and Exposition – Conference Preview on Bleeding & Clotting Disorders

The 66th ASH Annual Meeting and Exposition is set to take place from December 7-10, 2024, in San Diego, California, as well as online. This event stands as the premier hematology gathering of the year, attracting over 30,000 health professionals, clinicians, researchers, educators, and other industry experts. Attendees can expect a multitude of sessions, thousands […]

Guideline Spotlight - Adult Vaccination Schedule

CDC Adult Vaccination Schedule (2025) – Guidelines Spotlight 

Welcome to the latest edition of our Guideline Spotlight, where we delve into the significant changes and key takeaways from the Centers for Disease Control and Prevention’s (CDC) Adult Immunization Schedule for Ages 19 Years or Older, United States, 2025. This schedule serves as a valuable tool for healthcare providers to determine the recommended vaccines […]

Guideline Spotlight - Childhood & Adolescents Vaccination Schedule

CDC Childhood and Adolescent Vaccination Schedule (2025) – Guidelines Spotlight 

In this edition of our Guideline Spotlight, where we take a look into the significant changes and key takeaways from the Centers for Disease Control and Prevention’s (CDC) Recommended Childhood and Adolescent Immunization Schedule: United States, 2025. This schedule serves as a valuable tool for healthcare providers to determine the recommended vaccines for individuals within […]

Guidelines Side-By-Side Diabetic Retinopathy

Comparing Diabetic Retinopathy Guidelines – Guidelines Side-By-Side

Diabetic retinopathy, the most prevalent microvascular complication of both type 1 and type 2 diabetes, stands as a primary contributor to new cases of vision impairment among individuals aged 20 to 74 in the United States. This condition serves as the ocular manifestation of end-organ damage in diabetes mellitus. Factors that heighten the risk of […]

ACR 2024 Recap

ACR Convergence 2024 – Conference Recap on Gout

The American College of Rheumatology’s annual meeting, ACR Convergence 2024, was held from November 14 to 19 at the Walter E. Washington Convention Center in Washington, D.C. This prestigious event brought together leading experts in the field to exchange the latest advancements in rheumatology. At ACR Convergence 2024, several significant abstracts were presented focusing on […]

BAD Int'l Guidelines

British Association of Dermatologists (BAD) – Guidelines International Series

In this installment of our Guidelines International Series, we delve into the rich history of the British Association of Dermatologists (BAD), a venerable society established in 1919 by Sir Archibald Gray, then Editor of the British Journal of Dermatology. The BAD’s guiding principle, ‘healthy skin for all’, remains the cornerstone of their mission, although it […]

Guideline Timeline - Ulcerative Colitis Management

Ulcerative Colitis Management – Guidelines Timeline

Ulcerative colitis (UC) impacts nearly 2 million individuals in the United States. This chronic inflammatory bowel disease typically emerges in early adulthood and follows a pattern of relapsing and remitting symptoms. Unfortunately, up to 20% of patients may eventually require colectomy, and 33% may need hospitalization for disease management. Effectively controlling inflammatory activity is essential […]

AHA 2024 Conference Recap - Hypertension

AHA24 – Conference Recap on Hypertension

The American Heart Association’s (AHA) annual meeting, AHA24, was held from November 16-18, 2024, at the McCormick Place Convention Center in Chicago, Illinois. This prestigious event serves as the premier global platform for showcasing the latest advancements in cardiovascular science and medicine, providing attendees with the opportunity to engage with cutting-edge research and practice-changing educational […]

Guidelines+ Trials Spotlight - Kisqali HR+HER2 Early Breast Cancer Results (NATALEE)

Kisqali HR+/HER2- Early Breast Cancer Results (NATALEE) – Guidelines+ Trials Spotlight

On September 17, 2024, the US Food and Drug Administration (FDA) granted approval for Novartis’s Kisqali® (ribociclib) in combination with an aromatase inhibitor (AI) for the adjuvant treatment of individuals with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) stage II and III early cancer (EBC) at high risk of recurrence, including those with node-negative […]

ASCO’s Thyroid Cancer Guideline is Now Open for Public Comment

The American Society of Clinical Oncology (ASCO) has announced that the following guideline, “Systemic Treatment of Thyroid Cancer” is now open for public comment.  This latest guideline incorporates new evidence to ensure the most current recommendations are provided. As part of ASCO’s development process, they invite reviews and feedback for a 2-to-3-week period. Interested parties […]

Guidelines + Trials Rundown Actinic Keratosis

Actinic Keratosis in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on actinic keratosis in adults. The following list has been carefully curated by evaluating the ongoing phase 3 trials for actinic keratosis, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This […]

Guidelines Rundown - COPD

Chronic Obstructive Pulmonary Disease (COPD) – Guidelines Rundown (COPD Awareness Month)

Our Guidelines Rundown Series persists with a fresh article delving into the topic of chronic obstructive pulmonary disease (COPD) in recognition of COPD Awareness Month 2024. To aid in clinical decision-making, numerous societies have published extensive guidelines addressing different facets of COPD, such as nutrition management, COPD exacerbations, home oxygen therapy, and more. This article […]

Guidelines Rundown - Non-Cancer Bladder Health

Non-Cancer Bladder Health – Guidelines Rundown (Bladder Health Awareness Month)

The Urology Care Foundation, the official Foundation of the American Urological Association (AUA), is utilizing the month of November to address the stigma surrounding bladder health issues. Our goal is to provide resources that raise awareness and facilitate conversations between patients and their healthcare providers. In support of Bladder Health Awareness Month 2024, this edition […]

What's Changed Epilepsy

Epilepsy – What’s Changed

Each November, we commemorate National Epilepsy Awareness Month (NEAM), focusing on educating the public about epilepsy symptoms and supporting research efforts. In honor of NEAM, today’s article will focus on epilepsy. According to the Centers for Disease Control (CDC), between 2021 and 2022, approximately 2.9 million adults aged 18 and older reported experiencing active epilepsy, […]

Guideline Timeline - Stage IV NSCLC Without Driver Alterations

Stage IV NSCLC Without Driver Alterations – Guidelines Timeline

In the most recent edition of our Guidelines Timeline Series, we explore the American Society of Clinical Oncology’s (ASCO) guideline on Stage IV Non-Small Cell Lung Cancer without Driver Alterations, which was published on February 28, 2024. This guideline was introduced by ASCO as a living document, that is continuously updated to reflect the latest […]

Guidelines Side-By-Side Prostate Cancer

Comparing Prostate Cancer Guidelines – Guidelines Side-By-Side

Prostate cancer continues to be the most prevalent non-cutaneous cancer among men in the United States (US), with an estimated 268,490 new cases and 34,500 deaths projected for 2022. Given that the majority of newly diagnosed prostate cancer patients present with localized disease, it is crucial to provide evidence-based guideline statements to guide clinical decision-making […]

Guidelines Spotlight Gastropancreatic Neuroendocrine Tumors

Gastroenteropancreatic Neuroendocrine Tumors – Guidelines Spotlight

In this edition of our Guideline Spotlight, we will explore the key insights and takeaways from the American Society of Clinical Oncology’s (ASCO) comprehensive guideline, Systemic Therapy for Tumor Control in Metastatic Well-differentiated Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs). This guideline offers evidence-based recommendations for the treatment of advanced or metastatic GEP-NETs, a rare group of tumors […]

Guidelines Rundown - Epilepsy

Epilepsy – Guidelines Rundown (Epilepsy Awareness Month)

November is National Epilepsy Awareness Month (NEAM), a time dedicated to raising awareness about epilepsy and supporting research efforts. In honor of NEAM, our Guidelines Rundown Series presents a new article focusing on epilepsy. Epilepsy is a well-known condition that affects 1% of adults in the United States. According to the Centers for Disease Control […]

Fluticasone Furoate, Umeclidinium, & Vilanterol Inhalation Powder (Trelegy Ellipta/GSK) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication fluticasone furoate, umeclidinium, and vilanterol, marketed under the brand name Trelegy Ellipta by GlaxoSmithKline. Trelegy Ellipta is a combination of fluticasone furoate, an inhaled corticosteroid (ICS); umeclidinium, an anticholinergic; and vilanterol, a long-acting beta2-adrenergic agonist (LABA) indicated […]

Guidelines Rundown - Premature Birth

Premature Birth – Guidelines Rundown (National Prematurity Awareness Month)

November is recognized as National Prematurity Awareness Month, with World Prematurity Day being observed annually on November 17th to raise awareness about preterm birth. The incidence of preterm birth is increasing globally, with an estimated 15 million infants born preterm each year (more than 3 weeks early), as reported by the World Health Organization (WHO). […]

SCAI’s Guideline for the Management of Chronic Venous Disease is Now Open for Public Comment

The Society for Cardiovascular Angiography and Interventions (SCAI) has announced that the latest draft of the Clinical Practice Guidelines for the Management of Chronic Venous Disease is now available for public comment.  Chronic Venous Disease (CVD) is a condition that is often overlooked by healthcare providers, yet it can have a significant impact on patients’ […]

What's Changed Dravet Syndrome

Dravet Syndrome Guidelines – What’s Changed

Dravet syndrome is a rare form of epilepsy that typically manifests in infancy or early childhood. According to the National Institutes of Health (NIH), initial symptoms often present as either focal or generalized convulsive seizures that begin before the age of 15 months, with many cases occurring before the age of one. These initial seizures […]

Canadian Coalition for Seniors’ Mental Health (CCSMH) Int'l Guidelines

Canadian Coalition for Seniors’ Mental Health (CCSMH) – Guidelines International Series

In this installment of our Guidelines International Series, we will delve into the guidelines established by the Canadian Coalition for Seniors’ Mental Health (CCSMH). The CCSMH is committed to enhancing the quality of care and support for older adults throughout Canada. Their primary focus is on bridging gaps in knowledge and practice to ensure that […]

Guidelines Spotlight Non-Muscle Invasive Bladder Cancer

Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer – Guidelines Spotlight (Bladder Health Awareness Month)

In the United States, it is estimated that there will be 83,190 new cases of bladder cancer and 16,840 bladder cancer-related deaths in 2024. Approximately 25% of newly diagnosed patients are found to have muscle-invasive disease, a statistic that has remained relatively unchanged over the past decade according to data from the Surveillance, Epidemiology, and […]

What's Changed Prurigo Nodularis

Prurigo Nodularis – What’s Changed

Prurigo nodularis is a chronic skin condition that impacts an estimated 75,000 individuals in the United States (US). This condition is characterized by persistent and intense itching, significantly impacting the quality of life for those affected. Research has shown a higher prevalence of prurigo nodularis among individuals with certain comorbidities, such as mental health, endocrine, […]

Guidelines Side-By-Side Chronic Constipation

Comparing Chronic Constipation Guidelines – Guidelines Side-By-Side

Constipation is a prevalent gastrointestinal disorder, affecting approximately 15% of the global population. It is more commonly diagnosed in North America and Europe compared to Asia, likely due to variations in diet, culture, and environment. Risk factors for constipation include age over 65, female gender, sedentary lifestyle, low socioeconomic status, low-fiber diet, and non-White race. […]

ATA 2024 Conference Recap - Thyroid Eye Disease

ATA 2024 – Conference Recap on Thyroid Eye Disease (TED)

The 2024 American Thyroid Association (ATA) Annual Meeting took place from October 30 to November 3 in Chicago, IL. This event is globally recognized as the premier gathering for individuals interested in thyroid diseases and disorders. Attendees had the opportunity to engage in peer-to-peer learning and collaboration through a variety of activities including lectures, interactive […]

Aflibercept (Eylea/Regeneron) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication aflibercept, marketed under the brand name Eylea by Regeneron Pharmaceuticals, Inc. Eylea a is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (Wet) Age-Related Macular Degeneration (AMD), Macular Edema […]

Guidelines Rundown - Bladder Cancer

Bladder Cancer – Guidelines Rundown (Bladder Health Awareness Month 2024)

Welcome to the latest edition of our Guidelines Rundown Series, where we shine a spotlight on the most recent bladder cancer guidelines in recognition of Bladder Health Awareness Month 2024. Multiple medical societies have recently published comprehensive guidelines aimed at assisting healthcare professionals in making informed clinical decisions regarding the diagnosis and treatment of bladder […]

KDIGO’s Anemia in Chronic Kidney Disease Guideline is Now Open for Public Comment

Kidney Disease: Improving Global Outcomes (KDIGO) has announced that the latest draft of the Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD) is now available for public comment. This guideline is designed to educate and provide comprehensive guidance to healthcare professionals on diagnosing, evaluating, and treating anemia in adults and children with CKD, […]

AHA 2024 Conference Preview - Hypertension

Hypertension Sessions at AHA24 – Conference Preview

The American Heart Association’s (AHA) annual meeting, AHA24 will take place from November 16–18, 2024 at the McCormick Place Convention Center in Chicago, Illinois. This event serves as the leading global platform for the latest advancements in cardiovascular science and medicine, offering attendees the opportunity to engage with cutting-edge research and practice-changing educational content. We […]

ACG 2024 Conference Recap- Inflammatory Bowel Disease (IBD)

ACG 2024 – Conference Recap on Inflammatory Bowel Disease (IBD)

The American College of Gastroenterology’s Annual Scientific Meeting and Postgraduate Course, ACG 2024, took place in Philadelphia, PA from October 25-30, 2024. This esteemed event was designed to address the educational needs and priorities of clinical GI practitioners, showcasing the latest advancements in clinical GI, hepatology, and endoscopy. During ACG 2024, several key abstracts were […]

Guidelines + Journal Rundown COPD

Top Chronic Obstructive Pulmonary Disease (COPD) Articles – Guidelines+ Journals Rundown

For COPD Awareness Month 2024, we will be taking a closer look at some of the most popular COPD articles recently published in the leading pulmonology journals. The Impact of Changing Race-Specific Equations for Lung Function Tests among Veterans with Chronic Obstructive Pulmonary Disease Impact of Dyspnea on Adults with Respiratory Symptoms Without a Defined […]

ACR 2024 Preview - Gout

ACR Convergence 2024 – Conference Preview on Gout

The American College of Rheumatology’s annual meeting, ACR Convergence 2024, is set to take place from November 14 to 19 at the Walter E. Washington Convention Center in Washington, DC. This event will bring together top experts in the field to share the latest advancements in rheumatology. To secure your spot at this prestigious event, […]

Upcoming FDA Approvals & Decisions

Upcoming FDA Decisions – November 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

ACAAI 2024 Conference Recap - Allergic Skin Conditions

ACAAI 2024 – Conference Recap on Allergic Skin Conditions

The Annual Scientific Meeting of the American College of Allergy, Asthma, and Immunology (ACAAI) was held in Boston, MA from October 24-28, 2024. This prestigious event provided a platform for esteemed thought leaders to share their expertise and innovative ideas, fostering discussions and collaborations that are essential for driving progress in the healthcare field. A […]

Guideline Timeline - VA/DoD’s Stroke Rehabilitation

VA/DoD’s Stroke Rehabilitation 2024 vs 2019 – Guidelines Timeline

In our most recent edition of the Guidelines Timelines, we will be exploring the topic of stroke rehabilitation. In August 2024, the Department of Veterans Affairs (VA) and the Department of Defense (DoD) jointly released an updated clinical practice guideline (CPG) for the management of stroke rehabilitation for their healthcare providers. This new guideline serves […]

USPSTF’s Screening for Intimate Partner Violence and Caregiver Abuse Recommendation is Now Open for Public Comment

The United States Preventive Services Task Force (USPSTF) recently released their draft recommendation statement titled “Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults: Screening,” which was published online on October 29, 2024. In accordance with the latest screening guidelines, the USPSTF recommends that clinicians screen for intimate partner violence (IPV) in pregnant […]

Conference Recap (CNS 2024)

CNS 2024 – Conference Recap on Brain Tumors

The Cognitive Neuroscience Society (CNS) recently held its annual meeting, CNS 2024, from September 28th to October 2nd in Houston, Texas. This event provided attendees with the opportunity to delve into the latest advancements in neurosurgery and their impact on improving patient outcomes. The conference featured a lineup of distinguished speakers who delivered engaging and […]

Guidelines Rundown - HIV

Human Immunodeficiency Viruses (HIV) – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article that explores the topic of Human Immunodeficiency Viruses (HIV). To offer guidance and support for clinical decision-making, several societies and organizations have released comprehensive guidelines that cover various aspects of HIV, including preventing and treating opportunistic infections in people living with HIV, the use of antiretroviral […]

Guidelines Timeline - ACG Alcohol-Associated Liver Disease

ACG’s Alcohol-Associated Liver Disease 2018 vs 2024 – Guidelines Timeline

In this installment of our Guidelines Timelines Series, we will be conducting a comparative analysis of the American College of Gastroenterology’s (ACG) 2024 guideline on Alcohol-Associated Liver Disease in contrast to their previous 2018 version. Alcohol-associated liver disease (ALD) stands as a prominent cause of preventable liver-related morbidity and mortality on a global scale, including […]

Guidelines + Journal Rundown Radiation Oncology

Top Radiation Oncology Articles – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular radiation oncology-related articles recently published across medical journals. GEC-ESTRO Recommendations for Head & Neck Cancer Brachytherapy (Interventional Radiotherapy): 2nd Update With Focus on HDR and PDR Early-Stage Breast Cancer: A Critical Review of Current and Emerging Practice Clinical, Pathologic, […]

ACS Clinical Congress 2024 Conference Recap - Colon & Rectal Surgery

ACS Clinical Congress 2024 – Conference Recap on Colon and Rectal Surgery

The American College of Surgeons (ACS) hosted their Clinical Congress 2024 in San Francisco from October 19–22. This prestigious event provided a unique platform for education, networking, and exposure to cutting-edge surgical innovations that are shaping the field. Distinguished experts delivered a series of Named Lectures, covering a diverse range of topics within their respective […]

(MASCC) Int'l Guidelines

Multinational Association of Supportive Care in Cancer (MASCC) – Guidelines International Series

In this edition of our Guidelines International Series, we will be examining the guidelines from the Multinational Association of Supportive Care in Cancer (MASCC). MASCC is a global organization committed to advancing the practice, education, and research of supportive care in cancer. MASCC now includes members in over 70 countries around the world. With a […]

Guidelines Spotlight Advancing Genetic Testing in Kidney Diseases

Advancing Genetic Testing in Kidney Diseases – Guidelines Spotlight

In the United States, 37 million people suffer from chronic kidney disease, with 10% of adults and 70% of children affected by genetic causes. Despite advancements in genetic testing and a growing understanding of the genetic factors contributing to kidney diseases, genetic testing in nephrology lags behind other medical specialties. To address this gap, we […]

ASA 2024 Conference Recap - Pain Management & Anesthesia

Pain-Focused Sessions at ANESTHESIOLOGY 2024 – Conference Recap

The American Society of Anesthesiologists (ASA) recently hosted their annual meeting, ANESTHESIOLOGY 2024 (ANES), in Philadelphia, PA from October 18-22nd. This prestigious event offered attendees a unique opportunity to delve into cutting-edge ideas and innovations, achieve professional goals, and expand their network within the field of anesthesiology. ASA stands as a strong advocate for patients […]

Guideline Timeline - AHAASA Primary Stroke Prevention

AHA/ASA’s Primary Stroke Prevention 2024 vs 2014 – Guidelines Timeline

In this edition of our Guidelines Timeline series, we will explore the recently released 2024 Guideline for the Primary Prevention of Stroke by the American Heart Association (AHA) and American Stroke Association (ASA). This updated guideline supersedes the previous version from 2014, providing clinicians with a comprehensive resource to aid in the implementation of prevention […]

USPSTF Announces Breastfeeding Recommendation Statement is Now Open for Public Comment

The United States Preventive Services Task Force (USPSTF) has recently released their draft recommendation statement on breastfeeding interventions. The statement, titled “Breastfeeding: Behavioral Counseling Interventions,” was published online on October 22, 2024. According to the latest screening guidelines, the USPSTF recommends providing or referring pregnant and postpartum individuals to interventions that support breastfeeding. These recommendations […]

AACAP 2024 Conference Recap - Attention Deficit Hyperactivity Disorder (ADHD)

AACAP 2024 – Conference Recap on ADHD

The American Academy of Child and Adolescent Psychiatry (AACAP) Annual Meeting was held in Seattle, Washington from October 14-19, 2024. This prestigious event serves as the largest gathering of child and adolescent psychiatrists globally, providing a valuable opportunity to engage with and learn from peers and colleagues from over 60 countries. The AACAP 2024 Annual […]

Guidelines Rundown - Audiology Hearing Loss

Audiology / Hearing Loss – Guidelines Rundown (National Audiology Awareness Month 2024)

In honor of National Audiology Awareness Month 2024, our Guidelines Rundown Series will focus on the audiology/hearing loss related guidelines. Multiple societies have released comprehensive guidelines to provide guidance and support for clinical decision-making in the evaluation, diagnosis, and management of hearing loss in both adults and children. In this article, we will offer an […]

Vedolizumab (Entyvio/Takeda) – Guidelines+ Monographs

Welcome to the latest installment of our Guidelines+ Monographs Series. In this edition, we will delve into the medication vedolizumab, marketed under the brand name Entyvio by Takeda Pharmaceuticals. Entyvio is an integrin receptor antagonist indicated in adults for the treatment of moderately to severely active ulcerative colitis (UC) and moderately to severely active Crohn’s […]

Guidelines + Trials Rundown Urinary Tract Infection (UTI)

Urinary Tract Infection (UTI) in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on both uncomplicated and complicated urinary tract infections (UTIs) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for UTI, specifically targeting adults in the United States. Please note that the dates provided are approximate […]

Aripiprazole (Abilify Asimtufii/Otsuka) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication aripiprazole, marketed under the brand name Abilify Asimtufii by Otsuka Pharmaceutical Co., Ltd. Abilify Asimtufii (aripiprazole) is a long-acting injectable atypical antipsychotic for the treatment of schizophrenia and bipolar I disorder. It was initially approved in […]

Healthcare News & Research - October 2024

Healthcare News & Research – October 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Life Expectancy and Geographic Variation in Mortality: An Observational Comparison Study of Six High-Income Anglophone Countries Study Details | Source Upper Gastrointestinal Mucosal Damage and Subsequent Risk […]

Guidelines Spotlight Sport-Related Concussion (SRC)

Sport-Related Concussion (SRC) – Guidelines Spotlight

Sport-related concussion (SRC) is a prevalent injury in both recreational and organized sports. Over the past few decades, there has been significant advancement in our scientific comprehension of SRC, leading to the establishment of clinical recommendations for its diagnosis, assessment, and management. As the need for knowledgeable healthcare professionals to deliver evidence-based care for athletes […]

What's Changed Alopecia Areata

Alopecia Areata – What’s Changed

Alopecia areata is a prevalent autoimmune skin disease characterized by the development of patches of non-scarring hair loss. According to the National Alopecia Areata Foundation, nearly 7 million people in the United States (US) and 160 million worldwide are affected by alopecia areata or will be affected by it at some point. Currently, it is […]

Guidelines Side-By-Side Breast Cancer Screening

Comparing Breast Cancer Screening Guidelines – Guidelines Side-By-Side (Breast Cancer Awareness Month)

Among all women in the United States, breast cancer is the second most common cancer and the second leading cause of cancer-related deaths. In 2023, an estimated 43,170 women lost their lives to breast cancer. The incidence of breast cancer has been gradually increasing among women aged 40 to 49 years from 2000 to 2015, […]

What's Changed Pompe Disease

Pompe Disease – What’s Changed?

Pompe disease, also known as acid maltase disease and glycogen storage disease II, is a rare genetic disorder that results in progressive weakness in the heart and skeletal muscles. This debilitating condition is caused by mutations in a gene responsible for producing an enzyme called acid alpha-glucosidase (GAA). This enzyme plays a crucial role in […]

Guidelines Side-By-Side Early-Stage Breast Cancer

Insights from ASCO and ASTRO on Early-Stage Breast Cancer Management – Guidelines Side-by-Side

Breast cancer remains one of the most common cancers affecting women worldwide, with early detection playing a pivotal role in successful treatment and survival rates. Early-stage breast cancer, confined to the breast or nearby lymph nodes, presents opportunities for intervention that can significantly improve patient outcomes. In this article, we delve into the evolving landscape […]

Guidelines Rundown - Infection Prevention

Infection Prevention – Guidelines Rundown (International Infection Prevention Week 2024)

International Infection Prevention Week (IIPW) is an annual observance held every third week of October, with this year’s event taking place from October 20 to 26. The purpose of IIPW 2024 is to educate stakeholders and the general public on the critical importance of preventing the spread of illnesses and infectious agents. Infections, ranging from […]

Guidelines + Journal Rundown Psychiatry

Top Psychiatry Articles – Guidelines+ Journals Rundown

In recent years, psychiatry has seen significant advancements, with new research shedding light on the complexities of mental health, treatment innovations, and the challenges faced by both patients and healthcare providers. With mental health awareness on the rise and new treatment modalities being developed, it’s essential to stay updated on the latest findings. This article […]

Naltrexone (Vivitrol/Alkermes) – Guidelines+ Monographs

Welcome to the newest installment of our Guidelines+ Monographs Series. Today, we will be exploring the medication naltrexone, specifically the injectable form marketed under the brand name Vivitrol by Alkermes, Inc. Vivitrol is an opioid antagonist that was first approved in 2006. It is prescribed for the treatment of alcohol dependence and to block the […]

CHEST 2024 Recap

CHEST 2024 Conference Recap – Asthma

The American College of Chest Physicians (CHEST) recently held its annual meeting, CHEST 2024, from October 6 – 9 in Boston, Massachusetts. This esteemed event brought together top experts in the field of chest medicine, providing attendees with an exceptional educational experience and valuable networking opportunities aimed at improving patient care. A key focus of […]

ACG 2024 Conference Preview - Inflammatory Bowel Disease (IBD)

ACG 2024 – Conference Preview on Inflammatory Bowel Disease (IBD)

The American College of Gastroenterology’s Annual Scientific Meeting and Postgraduate Course, ACG 2024, will be held in Philadelphia, PA from October 25-30, 2024. This prestigious event will cater to the educational needs and priorities of clinical GI practitioners, covering the latest advancements in clinical GI, hepatology, and endoscopy. If you have not yet registered for […]

Int'l Guidelines - International Myeloma Working Group (IMWG)

International Myeloma Working Group (IMWG) – Guidelines International Series

In the latest edition of the Guidelines International Series, we explore the most recent guidelines published by the prestigious International Myeloma Working Group (IMWG). The IMWG is well known for its series of guidelines and recommendations that focus on the management and treatment of multiple myeloma and related disorders. With numerous research studies and treatment […]

Guidelines Spotlight Patients Hospitalized With Heart Failure

Patients Hospitalized With Heart Failure – Guidelines Spotlight

According to the Centers for Disease Control (CDC), nearly 6.7 million adults aged 20 years or older in the United States are affected by heart failure. In 2022, heart failure accounted for 13.9% of all causes of mortality. Heart failure is a serious condition with no known cure, but various treatments such as healthy lifestyle […]

ACAAI 2024 Conference Preview - Allergic Skin Conditions

ACAAI 2024 – Conference Preview on Allergic Skin Conditions

The Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) is set to take place in Boston, MA from October 24-28, 2024. The meeting serves as a platform for thought leaders to share their expertise and innovative ideas, sparking discussions and collaborations that can drive progress in the field of healthcare. […]

Guidelines Timeline - SIS Management of Intra-Abdominal Infection

2024 SIS Management of Intra-Abdominal Infection Guideline: What’s New & What’s Continued – Guidelines Timeline

Intra-abdominal infections (IAIs) remain a major clinical challenge, requiring precise management strategies. Over the years, guidelines from the Surgical Infection Society (SIS) have provided clinicians with evidence-based strategies to improve patient outcomes. The 2024 update of the SIS guideline on the Management of Intra-Abdominal Infection focuses on refining existing recommendations and providing new insights.   For […]

IDWeek 2024 Conference Preview

IDWeek 2024 – Conference Preview on COVID-19

IDWeek 2024 will take place from October 16-19, 2024, in Los Angeles, California. This prestigious event is the collaborative effort of the Infectious Diseases Society of America (IDSA), the Society for Healthcare Epidemiology of America (SHEA), the HIV Medicine Association (HIVMA), the Pediatric Infectious Diseases Society (PIDS), and the Society of Infectious Diseases Pharmacists (SIDP). […]

ASA 2024 Conference Preview - Pain Focused

Pain Management & Anesthesia – ANESTHESIOLOGY 2024 Conference Preview

The American Society of Anesthesiologists (ASA) will hold their annual meeting, ANESTHESIOLOGY 2024, from October 18-22nd in Philadelphia, PA. This event presents a unique opportunity to explore cutting-edge ideas and innovations, achieve professional goals, and expand your network within the field of anesthesiology. ASA serves as a strong advocate for patients in need of anesthesia […]

Brexpiprazole (Rexulti/Otsuka/Lundbeck) – Guidelines+ Monographs (August 2024 Edition)

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication brexpiprazole, marketed under the brand name Rexulti by Otsuka America Pharmaceutical, Inc and Lundbeck LLC. Rexulti, an atypical antipsychotic, received initial approval in 2015. It is indicated for  use as an adjunctive therapy to antidepressants for […]

ACEP 2024 Conference Recap- Ultrasound

ACEP 2024 Conference Recap – Emergency Ultrasound

The American College of Emergency Physicians (ACEP) hosted its 2024 Scientific Assembly from September 29 to October 2, 2024, at the Mandalay Bay Convention Center in Las Vegas, NV. This conference featured a variety of educational tracks tailored to enhance all aspects of emergency medicine practice. Today, we will be focusing on the research presented […]

ACS Clinical Congress 2024 Conference Preview - Colon & Rectal Surgery

ACS Clinical Congress 2024 – Conference Preview on Colon and Rectal Surgery

The American College of Surgeons is holding their Clinical Congress 2024 in San Francisco, CA from October 19–22. This event promises to offer a unique opportunity for education, networking, and exposure to the latest surgical innovations that are shaping the field. Renowned experts will deliver a series of Named Lectures, covering a wide range of […]

Guidelines + Trials Rundown: Advanced Hepatocellular Carcinoma (HCC) in Adults

Advanced Hepatocellular Carcinoma (HCC) in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on advanced hepatocellular carcinoma (HCC) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for HCC, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. […]

Guidelines Rundown - Depression

Depression – Guidelines Rundown (National Depression Screening Day)

Depression continues to be a serious mental health condition affecting millions of people worldwide, yet it often goes unnoticed and untreated. For those struggling, the weight of depression can feel overwhelming, impacting all areas of life—from relationships and work to personal well-being. In an effort to raise awareness and provide support, National Depression Screening Day […]

Conference Recap (AAP 2024)

2024 AAP National Conference & Exhibition Recap – Allergies & Vaccines

The 2024 American Academy of Pediatrics’ (AAP) National Conference & Exhibition was held from September 27 to October 1, 2024, in Orlando, FL. This event is a cornerstone for pediatric professionals, providing a plethora of educational opportunities such as updates on pediatric practice, cutting-edge research, and advocacy. Today, our focus is on the Vaccine & […]

ASTRO 2024 Conference Recap - Breast Cancer

Breast Cancer Insights from ASTRO 2024 – Conference Recap

The 2024 ASTRO Annual Meeting, held from September 28 to October 2 at the Walter E. Washington Convention Center in Washington, DC, brought together thousands of radiation oncology professionals. The conference, themed “Targeting Provider Wellness for Exceptional Patient Care,” gave attendees the opportunity to engage with leading experts and explore cutting-edge developments in radiation therapy, […]

Guidelines Spotlight ASCO Therapy for Stage IV Non-Small-Cell Lung Cancer With Driver Alterations

Therapy for Stage IV Non-Small-Cell Lung Cancer With Driver Alterations – Guidelines Spotlight

The American Society of Clinical Oncology (ASCO) is committed to developing dynamic guidelines for specific topic areas that continuously evolve with new research and evidence, resulting in frequent changes in recommended clinical practices. These living guidelines are regularly updated by a standing expert panel that systematically reviews health literature on an ongoing basis. In 2022, […]

AAO-HNSF Conference Recap - Rhinosinusitis

AAO-HNSF 2024 Annual Meeting Recap – Rhinosinusitis Research

The 2024 American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS) Annual Meeting & OTO EXPO took place from September 28 to October 1, 2024, in Miami Beach, Florida. This event serves as the premier gathering for AAO-HNS, providing attendees with the opportunity to stay informed about the latest research and best practices, participate in networking […]

What's Changed ADHD In Children & Adolescents

Attention Deficit Hyperactivity Disorder (ADHD) in Children and Adolescents – What’s Changed

Attention Deficit Hyperactivity Disorder (ADHD) affects an estimated 7 million (11.4%) children in the United States aged 3–17 years, as reported in a national survey of parents conducted in 2022. Nearly 6 in 10 children diagnosed with ADHD experience moderate to severe symptoms. Disturbingly, approximately 2 million children with ADHD did not receive specialized treatment […]

ASH’s Acute Lymphoblastic Leukemia in Adolescents and Young Adults Guidelines are Now Open for Public Comment

The American Society of Hematology (ASH) has announced that their draft recommendations on Frontline Management and Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) in Adolescents and Young Adults (AYAs) are now open for public comment. These guidelines have been developed to assist healthcare practitioners in the treatment and management of ALL in AYA patients. The ASH guidelines […]

Olaparib (LYNPARZA) – Guidelines+ Monographs

In this installment of our Guidelines+ Monographs Series, we will delve into the medication olaparib, marketed under the brand name Lynparza by AstraZeneca. Lynparza, is a poly ADP ribose polymerase (PARP) inhibitor for the treatment of ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. It was initially approved in 2014. In the following sections, […]

Guidelines Spotlight - Opioid Prescribing in Children & Adolescents

AAP’s Opioid Prescribing in Children and Adolescents – Guidelines Spotlight

The American Academy of Pediatrics (AAP) has recently published a clinical practice guideline (CPG) on Opioid Prescribing for Acute Pain Management in Children and Adolescents in Outpatient Settings. This marks a significant milestone for the AAP, as it is their inaugural CPG on opioid prescribing. The release of this guideline is particularly noteworthy given the […]

AACAP 2024 Conference Preview - Attention Deficit Hyperactivity Disorder (ADHD)

AACAP 2024 – Conference Preview on Attention Deficit Hyperactivity Disorder (ADHD)

The American Academy of Child and Adolescent Psychiatry (AACAP) Annual Meeting is scheduled to take place from October 14-19, 2024, in Seattle, Washington. This event is the largest gathering of child and adolescent psychiatrists worldwide, offering a unique opportunity to connect with and learn from colleagues and friends from over 60 countries. The AACAP’s 2024 […]

Upcoming FDA Approvals & Decisions

Upcoming FDA Decisions – October 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

EULAR Int'l Guidelines

European Alliance of Associations for Rheumatology (EULAR) – Guidelines International Series

The European Alliance of Associations for Rheumatology (EULAR), previously known as the European League Against Rheumatism, is a leading pan-European organization dedicated to improving the lives of people with rheumatic and musculoskeletal diseases (RMDs) through research, education, and advocacy. Founded in 1947, EULAR supports scientific research, and provides educational resources for healthcare professionals and patients. […]

Guidelines Side-By-Side Pediatric Obesity

Comparing Pediatric Obesity Guidelines – Guidelines Side-By-Side (Childhood Obesity Awareness Month)

Childhood obesity is a prevalent chronic disease affecting children today, with a complex etiology involving genetic, physiological, environmental, and socioeconomic factors. The increase in childhood obesity rates in the United States has been significant, rising from approximately 5% in the 1960s to over 19% according to recent estimates. This condition greatly increases the risk of […]

AGA’s First Guideline Utilizing AI is Now Open for Public Comment

The American Gastroenterological Association (AGA) has announced that their latest guideline, “AGA Clinical Practice Guideline on Computer-Aided-Detection Assisted Colonoscopy” is now open for public comment. This groundbreaking guideline represents AGA’s first comprehensive evaluation of the role of artificial intelligence (AI) in gastrointestinal care. This guideline’s intent is to assist healthcare practitioners by offering a detailed […]

Guidelines Spotlight AUA’s Salvage Therapy for Prostate Cancer

AUA’s Salvage Therapy for Prostate Cancer – Guidelines Spotlight

The American Urological Association (AUA), in partnership with the American Society for Radiation Oncology and Society of Urologic Oncology, released in February 2024 a clinical guideline focusing on salvage therapy for recurrent prostate cancer. This three-part series guideline is designed to assist clinicians in making informed care decisions for patients who experience cancer recurrence following […]

Guidelines Spotlight ACCAHA Perioperative Cardiovascular Management for Noncardiac Surgery

ACC/AHA’s Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery – Guidelines Spotlight 

Today, the American College of Cardiology (ACC) and the American Heart Association (AHA) Joint Committee on Clinical Practice Guidelines have released an updated guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery. This guideline supersedes the previous 2014 version and incorporates new evidence to provide clinicians with consolidated guidance. Clinicians are advised […]

Guidelines Rundown - Cholesterol Management

Cholesterol Management – Guidelines Rundown (National Cholesterol Education Month)

Our Guidelines Rundown Series continues with a new article that explores the topic of cholesterol management for National Cholesterol Education Month 2024. To offer guidance and support for clinical decision-making, several societies have released comprehensive guidelines that cover various aspects of cholesterol, including dyslipidemia, the role of non-statin therapies, nutrition, and more. In this article, we […]

CHEST 2024 Preview

CHEST 2024 – Conference Preview on Asthma

The American College of Chest Physicians (CHEST) is hosting its annual meeting, CHEST 2024. It will take place from October 6 – 9 in the vibrant city of Boston, Massachusetts. This prestigious event will bring together leading experts in the field of chest medicine, offering attendees an unparalleled educational experience and valuable networking opportunities aimed […]

Guidelines + Trials Rundown Ménière's Disease

Clinical Studies for Ménière’s Disease – Guidelines+ Trials Rundown

Ménière’s disease is a chronic inner ear disorder that affects balance and hearing, often causing vertigo, tinnitus, and hearing loss. While its exact cause remains unclear, the condition can significantly impact quality of life, prompting ongoing research to better understand and manage it. Over the years, various clinical trials have been conducted to explore potential […]

WGO Int'l Guidelines

The World Gastroenterology Organisation (WGO) – Guidelines International Series

In the most recent edition of the Guidelines International Series, we delve into the latest guidelines released by the World Gastroenterology Organisation (WGO). Established 90 years ago, the WGO is a federation comprising 119 Member Societies and four Regional Associations of gastroenterology, collectively representing more than 60,000 individual members globally. The organization’s mission is to […]

What's Changed Mild Intermittent Asthma in Adults

Mild Intermittent Asthma in Adults – What’s Changed

Intermittent asthma, or mild intermittent asthma, stands as the most prevalent form of asthma. Recent data from the Centers for Disease Control (CDC) reveals that over 20 million adults in the United States have been diagnosed with asthma. Among them, 8 million have encountered one or more asthma attacks within the past year, with 9% […]

Guidelines Spotlight AUA’s Incontinence After Prostate Treatment

AUA’s Incontinence After Prostate Treatment – Guidelines Spotlight

The American Urological Association (AUA) released its Incontinence after Prostate Treatment Guideline in June 2024 which we will be diving into in honor of National Prostate Cancer Awareness Month 2024. This updated guideline is designed to assist clinicians in making well-informed care decisions for patients experiencing incontinence following treatment for localized prostate cancer and benign […]

ACEP 2024 Conference Preview - Ultrasound

Emergency Ultrasound: ACEP 2024’s Expert-Led Sessions – Conference Preview

Get ready to immerse yourself in the forefront of emergency medicine at the American College of Emergency Physicians’ (ACEP) 2024 Scientific Assembly, taking place September 29 – October 2, 2024 at the Mandalay Bay Convention Center in Las Vegas, NV. This conference will offer a blend of educational tracks designed to enhance every facet of […]

Conference Preview (CNS 2024)

CNS 2024 – Conference Preview on Brain Tumors

CNS 2024 is the annual conference hosted by the prestigious Cognitive Neuroscience Society (CNS). The upcoming event is scheduled to take place from September 28th to October 2nd in Houston, Texas. This year’s conference is anticipated to be particularly engaging, offering attendees the opportunity to explore cutting-edge advancements in neurosurgery and their impact on enhancing […]

AAO-HNSF Conference Preview - Rhinosinusitis

AAO-HNSF 2024 Annual Meeting – Conference Preview on Rhinosinusitis

The 2024 American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS) Annual Meeting & OTO EXPO is set to take place from Saturday, September 28 to Tuesday, October 1, 2024, in Miami Beach, Florida. This event is the AAO-HNS’s flagship gathering, offering attendees the chance to stay abreast of cutting-edge research and best practices, engage in […]

Guidelines + Journal Rundown Hematology

Top Hematology Articles – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular hematology-related articles recently published across medical journals. Cancer diagnosis and treatment in working-age adults: Implications for employment, health insurance coverage, and financial hardship in the United States Asciminib Monotherapy as Frontline Treatment of Chronic-Phase Chronic Myeloid Leukemia: Results from […]

ASTRO 2024 Conference Preview - Breast Cancer

Breast Cancer Insights at ASTRO 2024 – Conference Preview

The 2024 ASTRO Annual Meeting takes place from September 28 – October 2 at the Walter E. Washington Convention Center, Washington, DC, and virtually. This year’s theme, “Targeting Provider Wellness for Exceptional Patient Care,” focuses on the connection between healthcare provider well-being and patient outcomes. With over 9,000 attendees expected, it’s the leading event for […]

Healthcare News & Research - September 2024

Healthcare News & Research – September 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults Study Details | Source Suicide Rates Among Physicians Compared With the General Population in Studies From 20 […]

Conference Preview (AAP 2024)

Essential Discussions on Allergies & Vaccines at the 2024 AAP National Conference & Exhibition – Conference Preview

The upcoming 2024 American Academy of Pediatrics’ (AAP) National Conference & Exhibition, set to take place live and virtually from September 27 to October 1, 2024, in the vibrant city of Orlando, FL, is an essential event for pediatric professionals. This conference offers a wealth of educational opportunities, including updates on pediatric practice, cutting-edge research, […]

Guidelines Spotlight Management of Patients with Atrial Fibrillation

Management of Patients With Atrial Fibrillation – Guidelines Spotlight

According to the American Heart Association (AHA), atrial fibrillation (AF) impacts between 2.7 and 6.1 million Americans, frequently resulting in heart-related complications and a fivefold increase in the risk of stroke. To address this significant health concern, the American College of Cardiology (ACC), and AHA, in collaboration with and endorsed by the American College of […]

Guidelines Rundown - Suicide Prevention

Suicide Prevention – Guidelines Rundown (Suicide Prevention Month 2024)

September 10th marks World Suicide Prevention Day 2024, an annual event organized by the International Association for Suicide Prevention (IASP). This significant day serves as a global platform to raise awareness about the preventability of suicide. In alignment with this theme, our Guidelines Rundown Series presents a new article focusing on suicide prevention guidelines. Various […]

Guidelines Timeline - AUA Early Detection of Prostate Cancer

AUA’s Early Detection of Prostate Cancer 2013 vs 2023 – Guidelines Timeline

The American Urological Association (AUA) stands as the leading urologic association, offering invaluable support to the global urologic community and its 23,000 members. Their mission is to advance the highest standards of urological clinical care through education, research, and the development of healthcare policies. AUA’s Clinical Practice Guidelines provide evidence-based guidance with a clear scope […]

ESC Int'l Guidelines

European Society of Cardiology (ESC) – Guidelines International Series

In the latest edition of the Guidelines International Series, we delve into the most recent guidelines published by the esteemed European Society of Cardiology (ESC). As a global leader in the field of cardiovascular medicine, the ESC brings together a community of over 100,000 scientists, clinicians, nurses, and allied professionals dedicated to advancing best practices […]

Niraparib (ZEJULA/GSK) – Guidelines+ Monographs

Ovarian cancer, the 5th leading cause of cancer deaths in the U.S., is one of the deadliest gynecologic malignancies due to its mild early symptoms, often leading to late detection. This edition of our Guidelines+ Monograph series explores niraparib (brand name Zejula) from GlaxoSmithKline (GSK), a once-daily oral (PO) PARP inhibitor. It’s FDA-approved as a […]

Guidelines Side-By-Side Hemophilia A & B Prophylaxis

Hemophilia A & B Prophylaxis – Guidelines Side-By-Side

Hemophilia A and B, the most common severe hereditary bleeding disorders, arise from deficiencies in factor VIII and factor IX, respectively. These conditions result in prolonged bleeding episodes, which can occur spontaneously or with minimal trauma, depending on the level of factor activity. Apart from treating acute bleeding, prophylaxis is a key strategy in hemophilia […]

Guidelines + Trials Rundown Ovarian Cancer

Ovarian Cancer in Adults – Guidelines+ Trials Rundown (Ovarian Cancer Awareness Month 2024)

This Ovarian Cancer Awareness Month 2024, we will be looking into the latest research and clinical trials focused on ovarian cancer in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for ovarian cancer, specifically targeting adults in the United States. Please note that the dates provided are approximate […]

Guidelines Spotlight Assessment management of POCS

Assessment and Management of Polycystic Ovary Syndrome – Guidelines Spotlight

The Centre for Research Excellence in Women’s Health in Reproductive Life (CRE WHiRL) collaborated with esteemed organizations such as the American Society for Reproductive Medicine (ASRM), Endocrine Society, European Society of Endocrinology (ESE), and European Society of Human Reproduction and Embryology (ESHRE), while collaborating with other professional societies. Together, they have enhanced the 2018 International […]

Guidelines Rundown - Sickle Cell Disease

Sickle Cell Disease – Guidelines Rundown (National Sickle Cell Awareness Month 2024)

This National Sickle Cell Awareness Month, our Guidelines Rundown Series continues with a new article that delves into the topic of sickle cell disease. Multiple societies have released comprehensive guidelines to provide guidance and support for clinical decision-making in the prevention, diagnosis, and management of sickle cell disease in both adults and children. In this […]

Naloxone Hydrochloride (NARCAN/Emergent) – Guidelines+ Monographs

The opioid crisis continues to be a major public health issue, with overdose rates still rising in many areas, particularly due to the increasing prevalence of synthetic opioids like fentanyl. This edition of our Guidelines+ Monograph series will be dedicated to International Overdose Awareness Day, a day on August 31st of each year dedicated to […]

Upcoming FDA Approvals & Decisions - September 2024

Upcoming FDA Decisions – September 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines Spotlight Patients Hospitalized with Heart Failure

2024 ACC Expert Consensus Decision Pathway on Clinical Assessment, Management, and Trajectory of Patients Hospitalized With Heart Failure Focused Update – Guidelines Spotlight

Updated Content from the 2019 ECDP Patients Hospitalized with Heart Failure In August 2024, the American College of Cardiology (ACC) published a focused update on the  Clinical Assessment, Management, and Trajectory of Patients Hospitalized With Heart Failure that harmonizes their 2019 ACC ECDP with the 2022 ACC/AHA Heart Failure guidelines to provide updated recommendations regarding […]

What's Changed Uncomplicated Urinary Tract Infections (UTIs) in Women

Uncomplicated Urinary Tract Infections in Women – What’s Changed

Patients with uncomplicated urinary tract infections (UTIs) do not have any structural abnormalities in their urinary tract or comorbidities such as diabetes, an immunocompromised state, recent urologic surgery, or pregnancy. An uncomplicated UTI is also referred to as cystitis or a lower tract UTI. It is estimated that approximately half of all women will experience […]

Medical Legal Rundown

Medical Legal Rundown (August 2024)

In this new series, we bring you the latest news stories that illustrate the complex intersections between healthcare and the legal system. From medical malpractice and patient rights to bioethics and regulatory challenges, we delve into how these two critical fields collide and interact. Join us as we navigate the multifaceted relationship between medicine and […]

ASCO’s Prostate Cancer Guidelines are Now Open for Public Comment

The American Society of Clinical Oncology (ASCO) has announced that the following guidelines, “Systemic Therapy in Men with Metastatic Castration-Resistant Prostate Cancer: ASCO Guideline Update” and “Germline and Somatic Genomic Testing in Metastatic Prostate Cancer: ASCO Guideline” are now open for public comment.  The Metastatic Castration-Resistant Prostate Cancer Guideline, is an update to ASCO’s 2014 […]

Guidelines + Journal Rundown Oncology Hematology Oncology

Top Oncology / Hematology Articles – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular oncology / hematology-related articles recently published across medical journals. Phase III KEYNOTE-789 Study of Pemetrexed and Platinum With or Without Pembrolizumab for Tyrosine Kinase Inhibitor‒Resistant, EGFR–Mutant, Metastatic Nonsquamous Non–Small Cell Lung Cancer First-Line Nivolumab Plus Relatlimab Versus Nivolumab Plus […]

AGA’s Hepatitis B Virus Reactivation Guideline is Now Open for Public Comment

The American Gastroenterological Association (AGA) has announced that their latest guideline, the “AGA Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in Immunosuppressed Individuals” is now open for public comment. This guideline, aimed at educating and providing guidance to frontline health practitioners on the prevention and management of Hepatitis B virus reactivation […]

ISTH Int'l Guidelines

The International Society on Thrombosis and Haemostasis (ISTH) – Guidelines International Series

In our latest installment of the Guidelines International Series, we will be looking at the latest guidelines from the International Society on Thrombosis and Haemostasis (ISTH). As the leading global organization in the field of bleeding and clotting disorders, ISTH plays a pivotal role in offering healthcare professionals and researchers worldwide with invaluable educational resources, […]

What's Changed & Predictions Gout

Gout – What’s Changed Since+ Predictions

Gout is a common medical condition characterized by the accumulation of monosodium urate (MSU) monohydrate crystals in the tissues, often resulting in painful flares that can last for one to two weeks. According to the National Institutes of Health (NIH), gout is more prevalent in men than in women and typically presents in middle age. […]

Guidelines Timeline - AAO Dry Eye Syndrome

Comparing the AAO Dry Eye Syndrome Preferred Practice Pattern – Guidelines Timeline

The American Academy of Ophthalmology (AAO) is the largest association of eye physicians and surgeons globally. Their mission is to protect vision and enhance quality of life by establishing the benchmarks for ophthalmic education and championing the interests of patients and the general public.   AAO regularly releases Preferred Practice Pattern® guidelines (PPP) aimed at defining […]

Guidelines Side-By-Side Bariatric Surgery

Comparing Bariatric Surgery Guidelines – Guidelines Side-By-Side

Affecting more than one-third of adults in the US, obesity remains a pressing health challenge for both providers and patients, conferring significant risk for comorbidities such as type 2 diabetes, obstructive sleep apnea, and cardiovascular disease. While lifestyle modifications and medical therapies, including anti-obesity medications (AOM), can be effective for some, they often fall short […]

Dapagliflozin (Farxiga/AZ) – Guidelines+ Monographs (August 2024 Edition)

In this edition of our Guidelines Monographs Series, we will be taking a look at AstraZeneca’s medication dapagliflozin, brand name Farxiga. Initially approved in 2014, Farxiga is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, provided to individuals with diabetes, heart disease, or kidney disease to improve their outcomes. This Guidelines+ Monograph will take a deeper dive […]

Guidelines+ Trials Spotlight - ITRAILBLAZER-ALZ 2

TRAILBLAZER-ALZ 2 Topline Results for the Treatment of Alzheimer’s Disease – Guidelines+ Trials Spotlight

On July 2, 2024, the US Food and Drug Administration (FDA) granted approval for Eli Lilly’s Kisunla (donanemab-azbt) injection for the treatment of Alzheimer’s disease. This treatment is recommended for patients in the early stages of the disease, specifically those with mild cognitive impairment or mild dementia, as demonstrated in the clinical trials. Kisunla marks […]

What's Changed & Predictions Hyperlipidemia

Pharmacological Management for Hyperlipidemia – What’s Changed Since+ Predictions

High cholesterol, also known as hyperlipidemia, affects millions of individuals in the United States (US). This condition can lead to serious health issues, such as an increased risk of heart disease and stroke. Globally, approximately one-third of cases of ischaemic heart disease are linked to high cholesterol levels. Elevated total cholesterol is a significant contributor […]

Guidelines Spotlight Immunization Schedules for Adults and Children

Immunization Schedules for Adults and Children – Guidelines Spotlight (National Immunization Awareness Month)

As we prepare for the National Immunization Awareness Month 2024 and upcoming autumn season, we will be conducting a thorough review of the United States Immunization Schedules for both Adults and Children. These crucial recommendations are released annually by the Centers for Disease Control and Prevention (CDC). They offer essential guidance on the recommended schedules […]

Guidelines + Journal Rundown Sleep Medicine

Top Sleep Medicine Articles – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular sleep medicine-related articles recently published across medical journals. Longer-term effect of physical activity intervention on sleep quality: a secondary analysis of cluster randomized controlled trial Delayed school start time is associated with better sleep, mental health, and life satisfaction […]

Healthcare News & Research - August 2024

Healthcare News & Research – August 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Aspirin Use and Incidence of Colorectal Cancer According to Lifestyle Risk Study Details | Source Impact of Inflammation on Cognitive Function in Patients With Highly Inflammatory Rheumatoid Arthritis […]

What's Changed Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) – What’s Changed?

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammation primarily affecting the synovial joints. This condition arises from an aberrant immune response targeting the synovium, leading to persistent inflammation, joint damage, and potential systemic manifestations. If left untreated, RA can cause significant damage to the joints and surrounding tissues, potentially leading to […]

AAN’s Migraine Prevention Guideline is Now Open for Public Comment

The American Academy of Neurology (AAN) has announced that their latest guideline, “Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Update: Report of the AAN Guidelines Subcommittee,” is now open for public comment. This practice guideline offers updated evidence-based conclusions and recommendations on the use of pharmacologic migraine prevention in adults. The primary objective […]

Guidelines Timeline - AGS Beers Criteria

Comparing the American Geriatrics Society (AGS) Beers Criteria – Guidelines Timeline

The American Geriatrics Society (AGS) Beers Criteria® for Potentially Inappropriate Medication (PIM) Use in Older Adults is a widely recognized and utilized tool in the healthcare community. The AGS Beers Criteria is regularly updated every 3-4 years to ensure its relevance and accuracy in guiding healthcare professionals in prescribing medications for individuals aged 65 and […]

Guidelines Rundown - Breastfeeding

Breastfeeding – Guidelines Rundown (National Breastfeeding Month 2024)

Our Guidelines Rundown Series continues with a new article that delves into the topic of breastfeeding in support of National Breastfeeding Month 2024. To provide guidance and clinical decision-making support on the matter, the Academy of Breastfeeding Medicine has published a comprehensive set of guidelines that address various aspects of breastfeeding, such as nutrition, supplements, […]

What's Changed & Predictions Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy – What’s Changed Since+ Predictions Series

Duchenne Muscular Dystrophy (DMD) is a severe inherited neuromuscular disorder caused by mutations in the dystrophin gene. It leads to progressive muscle wasting and irreversible functional decline. Primarily affecting males due to X-linked recessive inheritance, DMD can also rarely affect females. Symptoms include gradual muscle atrophy and fibrous tissue replacement in skeletal and cardiac muscles. […]

Guidelines + Trials Rundown: RSV Immunization in Adults

RSV Immunization in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on respiratory syncytial virus (RSV) immunization in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for RSV vaccinations, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject […]

Guidelines + Trials Rundown Multiple Myeloma

Multiple Myeloma in Adults – Guidelines+ Trials Rundown

In the latest edition of our Guidelines+ Trials Rundown Series, we delve into the most recent research and clinical trials focusing on multiple myeloma (MM) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for MM, specifically targeting adults in the United States. Please note that the dates […]

What's Changed & Predictions Thyroid Eye Disease (TED)

Thyroid Eye Disease (TED) – What’s Changed Since+ Predictions

Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex immune-mediated disorder characterized by the aberrant proliferation of orbital fibroblasts, adipogenesis, glycosaminoglycan and mucin deposition. This connective tissue remodeling results in edematous, fibrotic adipose tissue and inflammation within the orbit and underlies the consequential classic presentation of proptosis, where the eyes appear pushed […]

Guidelines Side-By-Side Obesity Rx

Anti-Obesity Medications – Guidelines Side-By-Side

Obesity remains a pervasive health challenge affecting a significant portion of the population worldwide, with implications extending beyond physical appearance to encompass profound metabolic and cardiovascular risks. As medical understanding evolves, the focus on effective weight management strategies has intensified, supported by advancements in pharmacotherapy.  As recommendations and anti-obesity medications (AOM) pharmacotherapies evolve, understanding the […]

Upcoming FDA Approvals & Decisions

Upcoming FDA Decisions – August 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines + Journal Rundown: Primary Care & Family Practice

Top Primary Care & Family Medicine: Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular primary care/family medicine-related articles recently published across medical journals. Morbidity and Mortality of Hospital-Onset SARS-CoV-2 Infections Due to Omicron Versus Prior Variants: A Propensity-Matched Analysis Is Prediabetes Overdiagnosed? Yes: A Patient-Epidemiologist’s Experience Is Prediabetes Overdiagnosed? No: A Clinician’s Perspective […]

What's Changed & Predictions Treatment of Patients With Schizophrenia

Treatment of Patients With Schizophrenia – What’s Changed Since+ Predictions Series

Among the top 10 causes of disability worldwide, schizophrenia’s relatively low prevalence is starkly contrasted by its profound impact on functional capacity and quality of life. With the National Institute of Mental Health estimating its prevalence in the US to range between 0.25% and 0.64%, schizophrenia is a disproportionately significant contributor to the global burden […]

Guidelines+ Trials Spotlight - Hidradenitis Suppurativa

Hidradenitis Suppurativa in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on hidradenitis suppurativa (HS) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for HS, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This […]

WHO Int'l Guidelines

The World Health Organization (WHO) – Guidelines International Series

In the latest installment of our Guidelines International Series, we will be delving into the latest guidelines from the World Health Organization (WHO). Established in 1948, WHO is a specialized agency of the United Nations (UN) that facilitates collaboration between nations, partners, and individuals to advance global health, ensure global security, and support marginalized populations. […]

Anesthesiology: Guidelines + Journals Rundown

Anesthesiology – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular anesthesiology-related articles recently published across medical journals. Increasing Sweep Gas Flow Reduces Respiratory Drive and Dyspnea in Nonintubated Venoarterial Extracorporeal Membrane Oxygenation Patients: A Pilot Study Postoperative Delirium and the Older Adult: Untangling the Confusion Failed spinal anesthesia for […]

Apixaban (Eliquis) – Guidelines+ Monographs (July 2024 Edition)

In this edition of our Guidelines+ Monographs Series, we will be taking a look at Bristol-Myers Squibb’s medication apixaban, brand name Eliquis. Initially approved in 2012, Eliquis is a factor Xa inhibitor, an anticoagulant used to prevent stroke and systemic embolism in nonvalvular atrial fibrillation, and to treat deep vein thrombosis (DVT) and pulmonary embolism […]

What's Changed - NCCN Soft Tissue Sarcoma (STS)

Soft Tissue Sarcoma – What’s Changed?

The American Cancer Society projects that in the United States alone in 2024, approximately 13,590 new cases of soft tissue sarcomas (STS) will be diagnosed, with 7,700 cases in males and 5,890 cases in females. Additionally, it is projected that about 5,200 individuals are expected to die from soft tissue sarcomas. It is important to […]

Guidelines+ Trials Spotlight - Soft Tissue Sarcoma

Soft Tissue Sarcoma – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to soft tissue sarcomas in adults. The below list was curated by assessing the ongoing Phase 3 trials for soft tissue sarcomas, specific to adults, and based in the United States. The dates provided are estimates, and subject to change. The list […]

ERS Int'l Guidelines

European Respiratory Society (ERS) – Guidelines International Series

Welcome to the second installment of the Guidelines International Series, where we will be delving into the European Respiratory Society (ERS). ERS stands as the largest respiratory medicine organization in Europe, with members hailing from 160 countries. As the premier membership organization for respiratory professionals, ERS is committed to advancing excellence in the study, research, […]

Guidelines + Journal Rundown OBGYN

Top Obstetrics & Gynecology Articles July 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular OBGYN-related articles recently published across medical journals. Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review Preliminary Efficacy of Topical Sildenafil Cream for the Treatment of Female Sexual Arousal Disorder: A Randomized Controlled Trial Amniocentesis in […]

Guidelines Rundown - Substance Use & Mental Health

Substance Use & Mental Health – Guidelines Rundown 

We understand the critical role you play in supporting patients and communities impacted by substance use and mental health disorders. To aid your efforts, we’ve compiled a comprehensive list of essential guidelines from leading medical societies published in recent years. These guidelines are designed to enhance your practice and improve patient outcomes. Your dedication to […]

Guidelines Rundown - Soft Tissue Sarcoma (STS)

Soft Tissue Sarcoma – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article dedicated to Sarcoma Awareness Month. Presently, there exists only a limited number of guidelines pertaining to Soft Tissue Sarcoma (STS), as they have only been released by a few medical societies. These guidelines offer recommendations on the management, treatment, and indications for radiation therapy for STS. […]

Guidelines Spotlight - Age-Related Hearing Loss

Age-Related Hearing Loss – Guidelines Spotlight

According to the National Institute on Deafness and Other Communication Disorders (NIDCD), age-related hearing loss (ARHL) or presbycusis is a prevalent condition among aging adults. Approximately 15% of American adults aged 18 and over report experiencing some degree of hearing difficulty, with one in three individuals between the ages of 65 and 74 experiencing hearing […]

Guidelines+ Trials Spotlight - Hemochromatosis

Advances in Hemochromatosis – Guidelines+ Trials Rundown

Today, we will explore the latest research and clinical trials focused on the management of hemochromatosis. The following list has been carefully curated by evaluating ongoing trials related to hemochromatosis in the United States. Please note that the dates provided are approximate and may be subject to change. The list primarily includes studies with results […]

Best Uses of AI LLMs in Guidelines Development

Top Ideas & Best Uses of AI / LLMs in Clinical Practice Guidelines Development

This article will examine a number of ideas and top suggestions for incorporating LLMs and AI, including Chatbots like GPT4 or Llama, into your clinical practice guidelines development process and workflows. As I’m sure you’ve heard, AI is improving and expanding rapidly, and that this is a moving target, so we’ll build upon this series […]

What's Changed & Predictions Age-Related Macular Degeneration

Age-Related Macular Degeneration Guidelines – What’s Changed Since & Guidelines Prediction Series

As the leading cause of irreversible blindness in adults 60 years of age and older, age-related macular degeneration (AMD) is a prevalent eye condition marked by central vision loss that impacts nearly 20 million individuals in the US. Despite its prevalence, afflicting approximately 1 in every 8 individuals above 60 years of age, there are […]

Guidelines Spotlight - Stimulant Use Disorder

Stimulant Use Disorder – Guidelines Spotlight

The American Society of Addiction Medicine (ASAM) and the American Academy of Addiction Psychiatry (AAAP) collaborated to develop the Clinical Practice Guideline on the Management of Stimulant Use Disorder (referred to as the Guideline). It was published on November 8, 2023. The Guideline aims to provide evidence-based strategies and clinically informed standards of care for […]

Guidelines + Journal Rundown Pediatrics

Top Pediatric Articles July 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular pediatric-related articles recently published across medical journals. Infant Deaths After Texas’ 2021 Ban on Abortion in Early Pregnancy Global Prevalence of Overweight and Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis Screening Accuracy of BMI for Adiposity […]

ACOG Pregnancy & Postpartum Algorithms

New Pregnancy and Postpartum Algorithms Published by ACOG

The American College of Obstetricians and Gynecologists (ACOG) and the Centers for Disease Control and Prevention (CDC) have collaborated on a multiyear initiative entitled “Identifying and Managing Obstetric Emergencies in Nonobstetric Settings.” This initiative addresses pregnancy-related emergencies and complications such as cardiomyopathy, preeclampsia, eclampsia, and stroke, as well as mental health conditions that can pose […]

AGA’s Ulcerative Colitis Guideline is Now Open for Public Comment

The American Gastroenterological Association (AGA) has announced that their latest guideline, “The AGA Living Guideline: Pharmacological Management of Moderate-To-Severe Ulcerative Colitis,” is now open for public comment. This guideline, aimed at supporting practitioners in the pharmacological management of moderate-to-severe ulcerative colitis (UC), features 14 recommendations designed to guide therapy decisions with a patient-centered approach. Referred […]

Guidelines Side-By-Side Psoriatic Arthritis

Analyzing Guidelines for Psoriatic Arthritis (PsA) – Guidelines Side-By-Side

Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory arthritis that occurs most commonly in some people with psoriasis, a skin condition characterized by red, scaly patches. Research suggests that approximately 20-30% of people with psoriasis also develop PsA, with the majority of patient’s presenting with skin-related disease that precedes the onset of arthritis symptomatology, though […]

Guidelines Spotlight - Vitamin D for the Prevention of Disease

Vitamin D for the Prevention of Disease – Guidelines Spotlight

The Endocrine Society unveiled its latest guideline, “Vitamin D for the Prevention of Disease,” on June 3rd, 2024. This evidence-based guideline aims to establish clinical guidelines for the use of vitamin D to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH)D testing. Recognized for its vital role […]

Upcoming FDA Approvals & Decisions - July 2024

Upcoming FDA Decisions – July 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines + Trials Rundown - Juvenile Arthritis

Advances in Juvenile Arthritis – Guidelines+ Trials Rundown

We’re going to take a look at the ongoing studies and clinical trials specific to juvenile arthritis. The below list was curated by assessing the ongoing Phase 3 trials for juvenile arthritis that are based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that have […]

Guidelines Spotlight - Melanoma & Gynecologic Cancer

SITC May 2024 Guidelines Updates for Melanoma & Gynecologic Cancer – Guidelines Spotlight

The Society for Immunotherapy of Cancer (SITC) recently released focused updates to two of its clinical practice guidelines. This edition of our Guidelines Spotlight series will examine the key changes that you need to be aware of.  Immunotherapy for the Treatment of Gynecologic Cancer Version 1.1 – Updated on May 24, 2024 Guideline Update Comments: […]

Guidelines Side-By-Side Migraine & Headache

A Comparative Analysis of Migraine & Headache Management Guidelines – National Migraine & Headache Awareness Month

National Migraine and Headache Awareness Month, observed in June, is an annual event that highlights the importance of utilizing evidence-based strategies when crafting patient-centered treatment plans for individuals grappling with headaches and migraines. With headaches ranking the 5th most common reason for emergency department visits, it is no surprise that the CDC estimates migraine disorder […]

ISTH 2024 Recap

ISTH 2024 Conference Recap – Venous Thromboembolism (VTE)

The International Society on Thrombosis and Haemostasis held its annual conference (ISTH 2024) in Bangkok, Thailand from June 22-26th. It is the premier global organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and hemostasis. During ISTH 2024, groundbreaking research on venous thromboembolism (VTE) was presented, showcasing the latest […]

Guidelines+ Trials Spotlight - Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA

Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA – Guidelines+ Trials Spotlight

According to the American Cancer Society, bladder cancer accounts for approximately 4% of all cancers in the United States, making it the fourth most common cancer in men and less common in women. The likelihood of men developing bladder cancer in their lifetime is about 1 in 28, while for women, the chance is about […]

Guidelines Spotlight - Epilepsy in Women

Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication – Guidelines Spotlight

A focused guideline update “Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication” was released by the American Academy of Neurology (AAN), the American Epilepsy Society (AES), and the Society for Maternal-Fetal Medicine (SMFM) on May 15, 2024. The new guideline updates the previous 2009 guideline for “Management Issues for Women with […]

Guidelines Side-By-Side IBS

Comparing AGA and ACG Guidelines for Irritable Bowel Syndrome (IBS) – Guidelines Side-By-Side

This week’s Guidelines Side-By-Side Series will compare the irritable bowel syndrome (IBS) guidelines from the two prominent GI-related associations in the United States – AGA and ACG. Below is an overview of the three guidelines that will be compared side-by-side. The AGA guidelines, while technically two separate documents, were published together at the same time. […]

Guidelines+ Journal Rundown Orthopedics

Top Orthopedics and Sports Medicine Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular orthopedics and sports medicine-related articles recently published across medical journals. Beneficial effects of exercise, testosterone, vitamin D, calcium and protein in older men-A randomized clinical trial Activity-Dependent Compensation at the Hip and Ankle at 8 Years After the Reconstruction […]

Guidelines+ Trials Rundown - Gout

Gout in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to gout in adults. The below list was curated by assessing the ongoing Phase 3 trials for gout, specific for adults, and based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that […]

SVSVAM 2024 Recap

VAM24 Conference Recap – The Latest Research on Aortic Disease

The 2024 Vascular Annual Meeting (VAM24) took place from June 19-22 in Chicago, Illinois, serving as the Society of Vascular Surgery’s (SVS) premier event. This meeting provided a plethora of valuable scientific content tailored to meet the needs of every member of the vascular care team. A key focus of VAM24 was aortic disease, encompassing […]

Upadacitinib (Rinvoq / AbbVie) and Current Clinical Guidelines – Guidelines+ Monographs

In this edition of our Guidelines+ Monographs Series, we will be taking a look at AbbVie’s medication Upadacitinib, brand name Rinvoq. Initially approved in 2019 Rinvoq is a Janus kinase (JAK) inhibitor used to treat a variety of conditions, including rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn’s disease, ankylosing spondylitis, and non-radiographic axial […]

Guidelines Timeline - Heart Failure with Reduced Ejection Fraction (HFrEF)

Comparing ACC Expert Consensus Pathways for Heart Failure with Reduced Ejection Fraction (HFrEF) – Guidelines Timelines

The American College of Cardiology (ACC), in collaboration with the American Heart Association (AHA), is renowned for its extensive publication of cardiology-related clinical practice guidelines. Alongside these guidelines, the ACC also produces Expert Consensus Decision Pathways (ECDPs), which are consensus-based documents aimed at providing valuable insights and recommendations in the field of cardiology. In this […]

Guidelines Rundown Multiple Myeloma

What’s New in Multiple Myeloma Guidelines – Guidelines Rundown

Multiple Myeloma, also known as Myeloma or Plasma Cell Myeloma, is a type of cancer that affects plasma cells, which are responsible for producing antibodies to protect against infections. This disease can present in various ways, ranging from a slow-developing form with minimal protein abnormalities and few malignant cells to a rapidly progressing and life-threatening […]

What's Changed & Predictions Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis Guidelines – What’s Changed Since+ Guidelines Prediction Series

EoE (eosinophilic esophagitis) is a chronic, immune-mediated condition characterized by mucosal inflammation and esophageal dysfunction as the result of an eosinophilic-predominant immunogenic reaction. EoE, with onset typically secondary to genetic predisposition or antigen-triggered in etiology, results in damage to the esophagus that symptomatically can present as dysphagia, odynophagia, episodes of choking episodes, or can be […]

Guidelines Spotlight - Survivorship Care for People Affected by Advanced or Metastatic Cancer

Survivorship Care for People Affected by Advanced or Metastatic Cancer – Guideline Spotlight

The Multinational Association for Supportive Care in Cancer and the American Society of Clinical Oncology (MASCC-ASCO) have recently published new guidelines entitled “Survivorship Care for Individuals Affected by Advanced or Metastatic Cancer,” on April 29, 2024. These guidelines provide comprehensive and evidence-based recommendations intended to improve the quality of life and optimize the outcomes for […]

Guidelines+ Journal Rundown Pulmonology

Top Pulmonology Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular pulmonology-related articles recently published across medical journals. Remission in asthma Electrocardiographic Abnormalities and Their Association with Outcomes in Randomized Clinical Trials of Pulmonary Arterial Hypertension DLco and echocardiographic parameters in identifying mild pulmonary hypertension in the EUSTAR cohort of […]

Healthcare News & Research - June 2024

Healthcare News & Research – June 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Regular use of fish oil supplements and course of cardiovascular diseases: prospective cohort study Study Details | Source A Gram-negative-selective antibiotic that spares the gut microbiome Study Details […]

Clinical Guidelines Implementation Strategy - Step 6 & 7: Measure & Evaluate, Change, Optimize & Repeat

Guideline Implementation Series: Final Steps (6-7) – Measure and Evaluate Change, Optimize, and Rinse and Repeat!

At this point you’ve not only planned your implementation initiative as discussed in our previous article, but you’ve also begun to actually implement it. A very critical (and often overlooked) step is to measure and evaluate your change, with a goal of optimization and iterative refinement and improvements. Also, to communicate your findings internally in […]

Guidelines Rundown Hepatitis

Hepatitis – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article focusing on hepatitis. There are many current guidelines on hepatitis, published from a dozen different medical societies. These guidelines encompass recommendations on hepatitis B and hepatitis C, as well as their impact on individuals with chronic kidney disease, cancer, and pregnancy. Let’s now explore the list […]

USPSTF Announces Proposed Osteoporosis Screening Recommendations

The United States Preventive Services Task Force (USPSTF) has recently unveiled a draft recommendation statement regarding Osteoporosis Screening, which was published online here on June 11, 2024. In their latest recommendations for osteoporosis screening, the USPSTF proposed the following: These updated recommendations closely align with the screening guidelines established in 2018 for the prevention of […]

Guidelines+ Journals Rundown Gastroenterology

Most Popular Gastroenterology Publications June 2024 – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular gastroenterology-related articles recently published across medical journals. Mechanisms of metastatic colorectal cancer A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial Mechanisms and management […]

ISTH 2024 Preview

ISTH 2024 Conference Preview – Venous Thromboembolism (VTE)

ISTH 2024 marks the 32nd Congress of the esteemed International Society on Thrombosis and Haemostasis (ISTH), set to take place in Bangkok, Thailand from June 22-26th. As the premier global organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and hemostasis, ISTH brings together over 7,000 clinicians, researchers, and […]

Guidelines+ Trials Spotlight - Produce

Food is Medicine & Produce Prescriptions – Guidelines+ Trials Spotlight

Nutrition plays a crucial role in maintaining overall health and well-being. A study from The Lancet revealed that poor diet is responsible for one in five deaths globally, contributing to a variety of chronic diseases such as cardiovascular diseases, cancer, and type 2 diabetes. Unfortunately, individuals with lower incomes, those residing in rural areas, and […]

Guidelines+ Trials Rundown - Celiac Disease

Celiac Disease in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to celiac disease in adults. The following list has been curated by evaluating the current Phase 2 and 3 clinical trials for celiac disease in adults conducted in the United States. Please note that the dates provided are approximate and may be […]

Guidelines + Trials Migraine Prevention

Migraine Prevention in Adults – Guidelines+ Trials Rundown

Today we’re going to cover the second article in a two part series that takes a look at the ongoing studies and clinical trials specific to management of migraine in adults, including acute migraine treatment and migraine prevention (both chronic migraine prevention and episodic migraine prevention).  The focus of Part 1 was Acute Migraine Treatment […]

ENDO 2024 Recap

Endocrine Society’s Annual Meeting Recap -Diabetes Research at ENDO 24

The Endocrine Society’s annual meeting, ENDO 2024, was held from June 1-4 in Boston, MA. This event served as a leading gathering for professionals in the field of endocrinology. The conference showcased esteemed experts and influential thought leaders who provided insightful presentations on cutting-edge research, treatments, and developments in endocrine disorders. Highlighted below are some […]

ASCO Conference Recap

2024 ASCO Annual Meeting Recap – The Latest Research on Lung Cancer

The Annual Meeting of the American Society of Clinical Oncology (ASCO) was held from May 31 to June 4, 2024, in Chicago, IL. This event serves as a pivotal gathering for healthcare professionals committed to enhancing patient care and outcomes within the field of oncology. A prominent topic of discussion at ASCO24 was lung cancer. […]

Guidelines+ Journals Rundown Neurology

Top Neurology Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular neurology-related articles recently published across medical journals. Burden of Stroke Attributable to Nonoptimal Temperature in 204 Countries and Territories Effect of Intermittent Oro-Esophageal Tube Feeding in Bulbar Palsy After Ischemic Stroke: A Randomized Controlled Study Downstream Biomarker Effects of […]

SVS: VAM 2024 Conference Preview

Vascular Annual Meeting (VAM24) – Conference Preview on Aortic Disease

The 2024 Vascular Annual Meeting (VAM24) will be held from June 19-22 in Chicago, Illinois. It is the Society of Vascular Surgery’s (SVS) premier meeting, offering a wealth of valuable scientific content tailored for every member of the vascular care team. If you have not already done so, we recommend registering here for this year’s […]

FDA Approvals - May 2024

Guideline Med Alerts & FDA Approvals – May 2024

Breyanzi (Bristol Myers Squibb)Expanded Indication Retevmo (Eli Lilly) Expanded Indication Onyda XR (Tris Pharma)  Bkemv (Amgen)Biosimilar to Soliris Opuviz (Biogen) Biosimilar to Eylea Yesafili (Biocon Biologics) Biosimilar to Eylea Imdelltra (Amgen)  Clinolipid (Baxter) Expanded Indication ColoSense (Geneoscopy) New Formulation Myhibbin (Azurity Pharmaceuticals) New Formulation Cyltezo (Boehringer Ingelheim) New Formulation Sign up for alerts and stay informed on […]

Upcoming FDA Approvals & Decisions - June 2024

Upcoming FDA Decisions – June 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

What's Changed - Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) Guidelines – What’s Changed

Amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig’s disease, is a neurological disorder that impacts the motor neurons responsible for controlling voluntary muscle movement and breathing, according to the National Institutes of Health (NIH). The Centers for Disease Control and Prevention (CDC) has reported that at least 16,000 Americans are affected by ALS. […]

BSH Int'l Guidelines

The British Society for Haematology – Guidelines International Series

In our first installment of our Guidelines International Series, we will be examining the British Society for Haematology (BSH). As the largest haematology organization in the United Kingdom (UK), boasting over 3,000 members worldwide, BSH is the premier membership organization for haematology professionals in the UK. BSH is dedicated to promoting excellence in the study, […]

Guidelines Rundown Multiple Sclerosis

Multiple Sclerosis – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article focusing on multiple sclerosis (MS). Currently, there are limited guidelines available on MS, all of which are provided by the American Academy of Neurology. These guidelines encompass a range of topics including vaccines and immunizations, therapies, alternative medicine, as well as the assessment and management of […]

Guidelines+ Journal Rundown Urology

Urology – Guidelines+ Journals Rundown (May 2024)

In this post, we will be taking a closer look at some of the most popular urology-related articles recently published across medical journals. Current and Emerging Strategies to Curb Antibiotic-Resistant Urinary Tract Infections A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy in Patients With Microhematuria. The Safe Testing of Risk for Asymptomatic […]

Guidelines + Trials Spotlight - Enhertu Metastatic Breast Cancer

Enhertu® Metastatic Breast Cancer Trial Results DESTINY-Breast06

According to the National Institutes of Health (NIH), around 13% of women will receive a cancer diagnosis at some stage in their lives. In 2021, an estimated 3,972,256 women were living with cancer in the United States. The most prevalent cancer subtype is HR+/HER2-, with an age-adjusted rate of 90 new cases per 100,000 women, […]

Guidelines Spotlight ACP Diabetes Guidelines

New 2024 ACP Diabetes Guidelines and the Removal of DPP4s – Guidelines Spotlight

The American College of Physicians (ACP) released a new clinical guideline on April 19, 2024, for Newer Pharmacologic Treatments in Adults With Type 2 Diabetes. This guideline focused specifically on three classes of medications commonly used for patients with Type 2 Diabetes Mellitus: While the guideline is relatively short, consisting of only three key recommendations, […]

Comparing Atopic Dermatitis Guidelines Side-By-Side

Comparing Atopic Dermatitis Guidelines – Guidelines Side-By-Side Series

For this installment of our Guidelines Side-By-Side Series, we’re going to take a look at the current guidelines for atopic dermatitis (AD), commonly referred to as eczema. It is a chronic inflammatory skin condition, identified by dry, itchy skin that may release clear fluid when scratched. The National Institutes of Health (NIH) estimates that this […]

Guidelines Rundown Tuberculosis

Tuberculosis – Guidelines Rundown

Our Guidelines Rundown Series progresses with a new article focused on tuberculosis. Numerous guidelines on tuberculosis are currently available, published by nearly a dozen different medical societies and organizations. The most recent guideline, issued by the World Health Organization, stands out as it leads the global initiative to eradicate tuberculosis by advocating for universal access […]

DDW 2024 Recap

DDW2024 Conference Recap: Crohn’s Disease and Ulcerative Colitis at Digestive Disease Week

The American Gastroenterological Association’s (AGA) annual meeting was held in Washington, DC from May 18-21, 2024. Digestive Disease Week® (DDW2024) is considered the leading event for gastroenterology professionals, featuring innovative advancements, networking opportunities, and the most recent research in the field. Today, we will explore some of the fascinating research presented at the DDW2024, with […]

AAFP Blood Pressure Targets in Adults With Hypertension Guidelines Spotlight

AAFP Blood Pressure Targets in Adults With Hypertension – Guidelines Spotlight

May is High Blood Pressure Education Month. High blood pressure, also known as hypertension, is a significant controllable risk factor for stroke and heart disease. In this article, we’re going to review the 2022 Blood Pressure Targets in Adults with Hypertension guideline from the American Academy of Family Physicians (AAFP) published on November 14, 2022. […]

HRS 2024 Conference Recap

HRS2024 Conference Recap – Pulsed Field Ablation at Heart Rhythm 2024

The Heart Rhythm Society’s 2024 Annual Meeting (HRS2024) was held in Boston from May 16-19, 2024. This prestigious event showcased cutting-edge research and advancements in the fields of cardiology and electrophysiology (EP). Today, we will explore some of the fascinating research presented at the HRS2024 Annual Meeting, with a specific focus on pulsed field ablation. […]

Healthcare News & Research - May 2024

Healthcare News & Research – May 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men: Individual Participant Data Meta-analyses Study Details | Source Consumption of Olive […]

Acute Migraine Guidelines + Trials Rundown

Acute Migraine Treatment in Adults – Guidelines+ Trials Rundown

Today we’re going to cover the first article in a two-part series that takes a look at the ongoing studies and clinical trials specific to management of migraine in adults, including acute migraine treatment and migraine prevention (both chronic migraine prevention and episodic migraine prevention).  For Part 1 we’ll be starting with Acute Migraine Treatment […]

Guidelines+ Trials Rundown Schizophrenia in Adults

Schizophrenia in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to management of schizophrenia in adults, including in acutely psychotic people with schizophrenia and relapse prevention. The below list was curated by assessing the ongoing Phase 3 trials for migraine treatments, specific for adults, and based in the United States. The dates […]

Menopause Guidelines Side-By-Side

Analyzing Guidelines for Menopause-Related Topics – Guidelines Side-By-Side

During Women’s Health Awareness Month, it is crucial to address menopause-related issues with informed strategies. The prevalence of vasomotor symptoms of menopause ranges from 50% to 82% among US women experiencing natural menopause. Additionally, genitourinary syndrome of menopause affects 27% to 84% of postmenopausal women. Breast cancer impacts approximately one in eight women in the […]

Clinical Guidelines Implementation Strategy - Improving Adherence

Guideline Implementation Series: Step 5 – Implementing the Strategies to Improve Adherence to the Selected Guideline Recommendations

Now that you’ve identified the barriers and prioritized specific interventions as discussed in our previous article on Step 4: Determining Interventions To Mitigate The Identified Barriers, it’s time to begin looking at actual implementation. This includes following through with the previous plans you’ve put in place, and the distribution of various resources to support your […]

Dupilumab (Dupixent) – Guidelines+ Monographs (May 2024 Edition)

This is our first post in a new series called “Guidelines+ Monographs”. In this series we provide an overview of a single medication or therapeutic agent, and then compare how it is positioned across all current guidelines that the medication is indicated for. This may be a single indication/guideline in some cases, or multiple indications […]

Guidelines Spotlight ACCAHA Peripheral Artery Disease (PAD)

New Lower Extremity Peripheral Artery Disease Guidelines 2024 – What’s Changed and Key Takeaways

The 2024 AHA/ACC Guideline on the Management of Lower Extremity Peripheral Artery Disease has been officially released today. This new guideline serves as an update to the previous “2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease,” incorporating the latest evidence to assist clinicians in providing comprehensive care for patients […]

Guidelines Rundown - Stroke Awareness Month 2024

Stroke – Guidelines Rundown (Stroke Awareness Month 2024)

In honor of Stroke Awareness Month, our ongoing Guidelines Rundown Series will be dedicated to the topic of stroke. There are a multitude of current guidelines on stroke, published from over a dozen different medical societies. These guidelines encompass strategies for prevention, management, and rehabilitation post-stroke. Below is the rundown of clinical practice guidelines on stroke: […]

Dermatology: Guidelines + Journal Rundown (May 2024)

Dermatology – Guidelines+ Journals Rundown (May 2024)

In this post, we will be taking a closer look at some of the most popular dermatology-related articles recently published across leading medical journals. Venous thromboembolism risk is lower in patients with atopic dermatitis than other immune-mediated inflammatory diseases: A retrospective, observational, comparative cohort study using US claims data Oral Minoxidil vs Topical Minoxidil for […]

Guidelines Side-By-Side Hepatocellular Carcinoma

Comparing Five Current Hepatocellular Carcinoma Clinical Guidelines – Guidelines Side-By-Side Series

For the next installment of our Guidelines Side-By-Side series, we’re going to take a look at the current guidelines for liver cancer. This article will examine how the recommendations in each guideline agree, contradict, or otherwise differ.  Our topic for today will be systemic treatment for metastatic hepatocellular carcinoma. The focus will be limited to […]

ENDO 2024 Conference Preview

ENDO 2024 Conference Preview – The Latest Developments in Diabetes

ENDO 2024, the Endocrine Society’s annual meeting will take place June 1-4 in Boston, MA.  It promises to be a cutting-edge event for professionals in the field of endocrinology. This conference will feature renowned experts and thought leaders delivering informative presentations on the latest research, treatments, and trends in endocrine disorders.  Before proceeding, if you […]

APA 2024 Conference Recap

2024 APA Annual Meeting Recap – Anxiety Disorders

The American Psychiatric Association (APA) hosted its prestigious 2024 Annual Meeting from May 4th to 8th in New York, NY. This event serves as a cornerstone for the psychiatry community, showcasing cutting-edge research and advancements in the field. Today, we will delve into some of the captivating research unveiled at the APA 2024 Annual Meeting, […]

Guidelines Spotlight Acne Vulgaris

Management of Acne – Guidelines Spotlight

Acne is one of the most prevalent skin conditions treated by dermatologists.  It is characterized as a chronic, inflammatory disease that can significantly impact the lives of patients. In January 2024, the American Academy of Dermatology (AAD) released Guidelines of Care for the Management of Acne Vulgaris to offer standardized, evidence-based recommendations for the treatment […]

Guidelines Spotlight ACCAHA Hypertrophic Cardiomyopathy (HCM)

New Hypertrophic Cardiomyopathy Guidelines 2024 – What’s Changed and Key Takeaways

A focused update to the ACC/AHA Hypertrophic Cardiomyopathy (HCM) Clinical Guidelines was released today. The new guidelines update the previous 2020 guidelines for Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy. Today we’ll take a look at what’s changed, as well as some of the key takeaways from the new 2024 HCM Guidelines. Before we […]

Mechanical Ventilation - Guidelines Rundown

Mechanical Ventilation – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article focusing on mechanical ventilation. There are many current guidelines on mechanical ventilation, published by over a half dozen different medical societies. These guidelines both cover mechanical ventilation in a broad sense, as well as in specific situations, such as prevention of VAP. Today we’re going to […]

Cardiology Guidelines + Journal Rundown Cardiology

Cardiology – Guidelines+ Journals Rundown (May 2024)

In this post, we will be taking a closer look at some of the most popular cardiology-related articles that have been published during the months of April and May 2024. Antibiotic Prophylaxis and Infective Endocarditis Incidence Following Invasive Dental Procedures Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association Stress […]

Treating Major Depressive Disorder - Guidelines Evolution

Treating Major Depressive Disorder – What’s Changed

In honor of Mental Health Awareness Month 2024, we will be examining the most recent guidelines on major depressive disorder (MDD). Surprisingly, there are not many US-based guidelines for the management of MDD. The most recent guideline was actually published by the Department of Veterans Affairs and the Department of Defense (VA/DoD) in April 2022. […]

Digestive Disease Week 2024

DDW Conference Preview – IBD at Digestive Disease Week® 2024

Digestive Disease Week® (DDW) will be held May 18-21, 2024, in Washington, DC. This annual event serves as the leading gathering for gastroenterologists, researchers, and industry professionals dedicated to improving outcomes for patients affected by gastrointestinal diseases.   Before proceeding, we strongly encourage you to register for the event by clicking here. This will allow you […]

ASCO Conference Preview 2024

ASCO24 Conference Preview – Lung Cancer at the ASCO Annual Meeting 2024

As we approach the kickoff of the 2024 ASCO Annual Meeting, we are taking a look at some of the “can’t miss” sessions, symposiums, presentations and more, specific to lung cancer. This includes Non-Small-Cell Lung Cancer (NSCLC) and Small-Cell Lung Cancer (SCLC), and both early and metastatic. Before we dive in, if you are an […]

What’s New in Infectious Diseases So Far Through April 2024 – Guidelines Rundown

Today, we will be providing an overview of the latest developments in the field of Infectious Diseases up to April 2024. This includes new medications, new guidelines, and noteworthy research and journal articles that have been published in the first four months of the year. Recent Infectious Diseases-Related Clinical Guidelines Recent Infectious Disease-Related FDA Medication […]

Upcoming FDA Decisions – May 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug or device applications. Below, you will find a list of drugs and devices, […]

Guidelines+ Journal Rundown Endocrinology

Endocrinology – Guidelines+ Journals Rundown (April 2024)

In this post, we will be taking a closer look at some of the most popular endocrinology-related articles that have been published during the month of April 2024. The American Society for Bone and Mineral Research Task Force on clinical algorithms for fracture risk report 2024 Abridged Diabetes Standards of Care Impact of insulin sensitization […]

HRS2024 Conference Preview – Atrial Fibrillation at Heart Rhythm 2024

The anticipation is building for Heart Rhythm 2024 (HRS2024), set to take place in Boston from May 16-19, 2024. The society’s annual meeting will delve into the latest groundbreaking research and advancements in the fields of cardiology and electrophysiology (EP).   If you have not already done so, we highly recommend registering for the event by […]

New FDA Medication Approval – Anktiva for NMIBC

On April 22, 2024, the US Food and Drug Administration (FDA) approved ImmunityBio’s first-in-class interleukin-15 superagonist (IL-15) nogapendekin alfa inbakicept-pmln (Anktiva), plus bacillus Calmette-Guérin (BCG), for the treatment of patients with BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS), with or without papillary tumors.  Designated an FDA Breakthrough Therapy, the novel immunotherapy […]

Alcohol Awareness Month 2024

Alcohol Awareness Month 2024 – Analyzing ASAM vs. APA Guidelines for Alcohol Withdrawal Management

As Alcohol Awareness Month unfolds, the imperative to address alcohol-related issues with informed strategies is a critical aspect often overlooked in discussions about alcohol abuse. In this article, we dive into a comprehensive analysis of two major guidelines published by the American Society of Addiction Medicine (ASAM) and the American Psychiatric Association (APA). By comparing […]

Clinical Guidelines Implementation Strategy

Guideline Implementation Series: Step 4 – Determining Interventions to Mitigate the Identified Barriers

In our previous article, we’ve identified the specific guideline(s) we’re focused on implementing, measured existing practices at the organization, and also identified any potential barriers to implementation, it’s time to focus on determination and prioritization of specific interventions.  Interventions may be targeted at one or more stakeholders, including: Strategies for implementation and specific interventions include […]

ACC Annual Conference 2024 - What's New in Heart Failure

ACC Conference 2024 Recap – What’s New In Heart Failure

The 73rd Annual Scientific Session & Expo of the American College of Cardiology took place from April 6-8, 2024, in Atlanta, GA. This event is a cornerstone for healthcare professionals dedicated to improving patient care and outcomes in the field of cardiology.  One of the key topics discussed at ACC24 was heart failure. According to […]

National Nutrition Month Blog - 2024

National Nutrition Month® 2024 – Empowering Patients Through Informed Nutritional Approaches

Informed food choices and dietary eating habits are essential to fighting diseases and maintaining a healthy lifestyle. Unhealthy menu items, such as sugar-sweetened beverages and highly processed food, can lead to weight gain, obesity, prediabetes and type 2 diabetes, all of which are risk factors for cardiovascular disease (CVD). Their increasing consumption is now leading […]

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Colorectal Cancer Awareness Month 2024 – A Patient’s Guide to Colorectal Cancer Screening 

Colorectal cancer (CRC) is a prevalent and potentially deadly disease that affects millions of individuals each year. In the United States alone, CRC ranks as the fourth most commonly diagnosed cancer among adults and the second leading cause of cancer-related deaths.  Despite its prevalence, CRC is highly preventable through early detection and screening. As clinicians, […]

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National Kidney Month 2024 – Essential Kidney Disease Guidelines (2020 – Present)

850 million people in the world have kidney disease. Yet, few are aware of its dangers. On average, kidney disease affects one in nine people with most of them not even being aware of it. This lack of early detection can be fatal as kidney dysfunction that lasts longer than three months most often is […]

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Essential Cancer Prevention and Screening Guidelines You Can’t Miss! National Cancer Prevention Month 2024

Join us as we combat the staggering statistics of cancer. With over 600,000 lives lost last year, and 40% of cases preventable, the urgency is clear. This April, in honor of National Cancer Prevention Month 2024, we’re assembling various cancer-related screening and prevention guidelines to help the fight against this devastating disease.  Together, let’s turn […]

American Heart Month 2024: What’s New and Upcoming in American Heart Association Guidelines Hero Image

American Heart Month 2024: What’s New and Upcoming in American Heart Association Clinical Guidelines

February is American Heart Month, a time when all people are encouraged to focus on their cardiovascular health. Cardiovascular disease (CVD) isn’t exclusive to older adults. Data show that CVD and CVD mortality are increasing among younger populations. 1 in every 3 deaths in the United States is related to cardiovascular disease. For American Heart […]

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2023 in Review: Top Clinical Guidelines and Breakthroughs 

Hundreds of clinical practice guidelines are published each year. In 2023, a total of 224 guidelines were published in the United States alone marking a 16% increase from prior year. We’ve seen a spike in guidelines being published in the months of May (32 guidelines) and August (24 guidelines) in 2023 versus a spike of […]

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Diabetes Awareness Month 2023: New Diabetes Clinical Guideline Updates

November is National Diabetes Awareness Month and November 14th marks World Diabetes Day, an opportunity to raise awareness around diabetes prevention and fighting this disease. About 37 million Americans are impacted by this disease which can affect the heart, kidneys, & nerves.   For National Diabetes Month 2023, we’ve put together a list of all […]

Lung Cancer Awareness Month Guidelines Hero Image

Lung Cancer Guidelines for Lung Cancer Awareness Month 2023 – Clinical Practice Guideline Round Up

November marks Lung Cancer Awareness Month and November 11 is dedicated to National Lung Cancer Awareness Day. Lung cancer is the leading cause of cancer death among men and women in the United States, accounting for more deaths than colon cancer, breast cancer and prostate cancer combined. There are two main forms of lung cancer […]

Liver Cancer Guidelines for Awareness Month 2023 – Clinical Practice Guideline Round Up

October is Cancer Awareness Month as well as Liver Cancer Awareness Month. Hepatocellular Carcinoma, (HCC for short), or Liver Cancer, is the third most deadliest cancer in the United States. Each year, tens of thousands of new cases are reported, and as many as 30,000 deaths caused by HCC alone.  For Liver Cancer Awareness Month […]

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Breast Cancer Awareness Month 2023 – The Latest Clinical Guidelines and FDA Drug Approvals for Breast Cancer

October is Breast Cancer Awareness Month, and October 13, 2023 is National Metastatic Breast Cancer Awareness Day. An important month that is recognized by nearly all of the leading professional and patient-facing organizations including advocacy groups representing oncology, women’s health, breast cancer survivors and all the related healthcare professionals. This includes respected organizations like American […]

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New Clinical Practice Guidelines & FDA Drug Approvals – September 2023

Management of Endometrial Intraepithelial Neoplasia or Atypical Endometrial Hyperplasia Author:American College of Obstetricians and Gynecologists (ACOG) Published:September 1, 2023 Outpatient Treatment of Confirmed COVID-19 Author:American College of Physicians (ACP) Published:September 19, 2023 Optimal Timing of Elective Hip or Knee Arthroplasty for Patients with Symptomatic Moderate to Severe Osteoarthritis or Advanced Symptomatic Osteonecrosis with Secondary Arthritis […]

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10 New Heart Health Guidelines for World Heart Day 2023

Every year cardiovascular disease claims million of lives worldwide. World Heart Day, which is celebrated globally on September 29th serves as a reminder to prioritize heart health and take measures against heart disease. This occasion offers an opportunity to raise awareness about the significance of maintaining the heart, educating individuals on factors that affect global […]

Prostate Cancer Awareness Month 2023 – What’s New in Prostate Cancer Clinical Guidelines

September is Prostate Cancer Awareness Month. Prostate cancer is the second most common cancer among men, and 1 in 9 men will be diagnosed with prostate cancer during their lifetime. Prostate cancer is the leading site of new cancers diagnosed and the number two cause of death for males. For Prostate Cancer Awareness Month 2023 […]

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National Ovarian Cancer Awareness Month 2023 – What’s New in Clinical Guidelines for Ovarian Cancer Awareness Month

September is Ovarian Cancer Awareness Month. According to the Centers for Disease Control and Prevention (CDC), ovarian cancer is the second most common gynecologic cancer in the United States and causes more deaths than any other cancer of the female reproductive system. In this article, we will be taking a look at the current clinical […]

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New Clinical Practice Guidelines & FDA Drug Approvals – August 2023

Folic Acid Supplementation to Prevent Neural Tube Defects: Preventive Medication Author:United States Preventive Services Task Force (USPSTF) Published:August 2023 Prevention of Acquisition of HIV: Preexposure Prophylaxis Author:United States Preventive Services Task Force (USPSTF) Published:August 2023 Palliative Care for People with Chronic Obstructive Pulmonary Disease or Interstitial Lung Disease Author:European Respiratory Society (ERS) Published:August 17, 2023 […]

Guideline Implementation Series: Step 3 – Identify Potential Barriers (& Enablers) to Implementing the Recommendation

Through Step 2 you’ve now collected data about your organization relevant to the recommendation you want to implement. Getting to know the current state of your institution is foundational for implementing your chosen recommendation, but so is having a shared structure for change when beginning the transformation process.  Consequently, Step 3 is where we address […]

2023 Immunization Guidelines & Schedules – Immunization Awareness Month

National Immunization Awareness Month (NIAM) is an annual observance held in August to highlight the importance of routine vaccination for people of all ages. Last year’s post highlighted select immunization guidelines. This year we are focusing on the changes and updates made by the Centers for Disease Control and Prevention (CDC) to the updated 2023 […]

New Clinical Practice Guidelines & FDA Drug Approvals – July 2023

Lipid Disorders in Children and Adolescents: Screening Author:United States Preventive Services Task Force (USPSTF) Published:July 2023 Implementing Strategies to Prevent Infections in Acute-Care Settings Author:Infectious Diseases Society of America (IDSA); Society for Healthcare Epidemiology of America America (SHEA) Published:July 11, 2023 Vulnerabilities in Older Patients Receiving Systemic Cancer Therapy Author:American Society of Clinical Oncology (ASCO) […]

World Hepatitis Day 2023

World Hepatitis Day 2023 – Current Guidelines & Best Practices

July 28, 2023 marks World Hepatitis Day – a day recognized by the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) as well as many other reputable organizations across the globe to raise awareness for the worldwide burden of hepatitis A, hepatitis B, hepatitis C and other viral hepatitis in general.  […]

New Clinical Practice Guidelines & FDA Drug Approvals – June 2023

Anxiety Disorders in Adults: Screening – Adults 64 Years or Younger Author:United States Preventive Services Task Force (USPSTF) Published:June 2023 Anxiety Disorders in Adults: Screening – Older Adults 65 Years or Older Author:United States Preventive Services Task Force (USPSTF) Published:June 2023 Depression and Suicide Risk in Adults: Screening – Adults 64 Years or Younger Author:United […]

Guideline Implementation Series: Step 2 – Measuring Current Practice At Your Institution

A while back, we kicked off a 7-step approach on how to implement guidelines or any specific guideline recommendations with an organization. We also looked closely at the first step of the process on how to identify some of these guideline as well as some factors to consider when determining guideline implementation priorities. We have […]

New Clinical Practice Guidelines & FDA Drug Approvals – May 2023

Addressing Stigma and Bias in the Diagnosis and Management of Patients with Obesity/Adiposity-Based Chronic Disease and Assessing Bias and Stigmatization as Determinants of Disease Severity Society:American Association of Clinical Endocrinologists (AACE) Published:May 4, 2023 Health Advisory on Social Media Use in Adolescence Society:American Psychological Association (APA) Published:May 9, 2023 2023 Comprehensive Type 2 Diabetes Management […]

Bridging The Gap Between HCPs and Clinical Practice Guidelines

How Often Do HCPs Reference Clinical Practice Guidelines? For What Use Cases? What Are The Most Preferred Formats? How Do HCPs Learn About New Guidelines? Full-Text Guidelines VS. Summarized Versions? Research on Clinical Practice Guidelines: HCP Preferences, Usage, Preferred Formats, Adherence, & Strategies to Promote Guideline Implementation. We asked all these questions to clinicians spanning […]

Guideline Implementation Series: Step 1 – Identify the Guideline Recommendation(s) that You Wish to Implement

In a follow up to our previous article – Guideline Implementation Overview: 7 Steps to Improve Clinical Guideline Adherence at your Organization – we are taking a deeper dive into the first step – identifying the key guidelines/guideline recommendation to implement.  STEP 1 is actually a multi-part step, so we will be breaking STEP 1 […]

Lupus Awareness Month

National Lupus Awareness Month 2023 – What’s New in Clinical Guidelines for Lupus Awareness Month

May is Lupus Awareness Month. From 1977-2009, Lupus Awareness Month was originally observed in September. In 2009 the Lupus Foundation of America declared May would be the new official month for Lupus Awareness. Lupus is a chronic disease that affects individuals from all walks of life. It is an autoimmune disorder that causes the body’s […]

New Clinical Guidelines & FDA Drug Approvals – April 2023

Skin Cancer: Screening Society:U.S. Preventative Services Task Foce (USPSTF) Published:April 18, 2023 COVID-19 Guideline Part 1: Treatment and Management Society:Infectious Diseases Society of America (IDSA) Published:April 13, 2023 Use of Antiretroviral Agents in Pediatric HIV Infection Society:United States Department of Health and Human Services (DHHS) Published:April 12, 2023 Management of REM Sleep Behavior Disorder Society:American […]

Guideline Implementation Overview: 7 Steps to Improve Clinical Guideline Adherence at your Organization

In a bit of a deviation from the norm, rather than inform our readers of specific guideline recommendations, we wanted to provide a stepped approach for various best practices on how you can implement guidelines or specific guideline recommendations within your organization. As most know, the publication of a new guideline does not equate to […]

IBS Awareness Month & World IBS Day – April 2023: Best Practices and Recommendations for IBS Treatment and Management

If the majority of patients report that they would be willing to give up 10 to 15 years of their life expectancy just for an instant cure for their Irritable Bowel Syndrome (IBS), it gives healthcare providers pretty clear insight into how impactful and potentially debilitating this condition can be on a patient’s quality of […]

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New Clinical Guidelines & FDA Drug Approvals – March 2023

Probiotics and Prebiotics Society:World Gastroenterology Organisation (WGO) Published:March 1, 2023 Obesity Algorithm 2023 Society:Obesity Medicine Association (OMA) Published:March 1, 2023 Colorectal Cancer Screening Guidelines Toolkit Society:Consensus and Physician Experts (CPE) Published:March 1, 2023 COVID-19 Guideline, Part 1: Treatment and Management Society:Infectious Diseases Society of America (IDSA) Published:March 14, 2023 Comprehensive Adult Eye and Vision Examination […]

World TB Day 2023

World Tuberculosis Day 2023: Effective Guideline Recommendation Strategies For Managing TB

As World Tuberculosis Day or World TB Day approaches on March 24th, it’s important to remember that tuberculosis (TB) remains a significant global health issue. Prior to the COVID-19 pandemic, TB was the leading cause of death from a single infectious agent, ranking above HIV/AIDS.  The United States has one of the lowest TB incidence […]

Colorectal Cancer Awareness Month 2023: Screening Guidelines Highlighting The Differences and Similarities of 8 Colorectal Cancer Screening Guidelines

The month of March is dedicated to National Colorectal Cancer Awareness Month – an annual campaign aimed at increasing awareness of colorectal cancer (CRC) and the importance of cancer screenings, as well as promoting healthy lifestyle habits for primary prevention in reducing the risk of developing CRC. Despite being the 2nd leading cause of cancer-related […]

World Obesity Day 2023 – Changing Perspectives: A Clinical Practice Guidelines Approach to Obesity Care

World Obesity Day is an annual event intended to unify healthcare communities in rallying behind the common goal of tackling the obesity crisis. The theme for World Obesity Day 2023 is “Changing Perspectives: Let’s Talk Obesity”, which focuses on harnessing the power of conversation and obesity awareness to improve obesity care by addressing misconceptions and […]

New Clinical Guidelines & FDA Drug Approvals – February 2023

Genital Herpes Infection: Serologic Screening Society:U.S. Preventive Services Task Force (USPSTF) Published:February 2023 Management of Patients With Acute Lower Gastrointestinal Bleeding Society:American College of Gastroenterology (ACG) Published:February 6, 2023 Strategies to Prevent Healthcare-Associated Infections: Hand Hygiene Society:Infectious Diseases Society of America (IDSA); Society for Healthcare Epidemiology of America (SHEA) Published:February 8, 2023 Disorders of Lipid […]

Low Vision and Rehabilitation: Clinical Guidelines for Low Vision Awareness Month 2023

February is Low Vision and Vision Rehabilitation Awareness Month. Low vision refers to uncorrectable reduced vision that persists despite corrective glasses, lenses, medications, or surgery. This impaired vision interferes with a person’s functional independence in performing daily activities, and often leaves patients feeling helpless and hopeless about how to improve their function and quality of […]

New Clinical Guidelines & FDA Drug Approvals – January 2023

Immunotherapy & Targeted Therapy for Advanced Gastroesophageal Cancer Society:American Society of Clinical Oncology (ASCO) Published:January 5, 2023 Vaccinations in Patients with Rheumatic & Musculoskeletal Diseases Society: American College of Rheumatology (ACR) Published:January 4, 2023 Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults Society:American College of Physicians (ACP) Published:January 3, […]

Cervical Cancer Guidelines for Cervical Cancer Awareness Month 2023

Even though it is preventable, more than 15,000 women in the United States alone are diagnosed each year with cervical cancer, a potentially fatal condition that can be caused by infections with pathogens – bacteria, viruses, and parasites. January is World Cervical Cancer and Cervical Health Awareness Month – a dedicated month with a special […]

New Clinical Guidelines & FDA Drug Approvals – December 2022

Antiretroviral Drugs for Treatment & Prevention of HIV Infection in Adults Society:International Antiviral Society–USA (IAS-USA) Published:December 1, 2022 Standards of Care in Diabetes – 2023 Society: American Diabetes Association (ADA) Published:December 12, 2022 Interventional Treatments for Low Back Pain Society:American Society of Pain and Neuroscience (IASPN) Published:December 6, 2022 Monitoring and Antagonism of Neuromuscular Blockade […]

Top 10 Most Viewed Clinical Practice Guidelines on the Guideline Central Platform in 2022

In our previous article, we looked at some of the high level data points covering clinical practice guidelines published in 2022. In this post, we will break down the all-time most viewed guidelines (on the Guideline Central platform), regardless of release date. So, without further ado… ACC/AHA Heart Failure (166,000 views) The American College of […]

Yearly Clinical Guidelines – Stats and Recap for 2022

Introducing our new Yearly Recap series, intended to highlight the key data and trends in the world of clinical practice guidelines, we will kick it off with our first article that will cover some of the main data points relating to guidelines that were published in 2022. Keep in mind, this list is focused only […]

New Clinical Guidelines & FDA Drug Approvals – November 2022

CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 Society:Centers for Disease Control and Prevention (CDC) Published:November 4, 2022 Clinical Assessment of Patients with Inherited Retinal Degenerations Society: American Academy of Ophthalmology (AAO) Published:November 1, 2022 Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science Society:International Liaison Committee on Resuscitation (ILCOR) Published:November 3, […]

COPD Clinical Guidelines Roundup for World COPD Day 2022

November 16, 2022 is World COPD Day – a day organized by GOLD (Global Initiative for Chronic Obstructive Lung Disease) to help raise awareness of COPD across the globe.  This World COPD Day 2022, we are taking a deep dive into all of the current COPD guidelines from various organizations in the USA. This includes […]

National Diabetes Month 2022 – What’s New in Clinical Guidelines for Diabetes Awareness Month

November is Diabetes Awareness Month or National Diabetes Month. In this article, we will take a look at all of the new guidelines, therapies and innovations that have been introduced since Diabetes Awareness Month 2021.  Guidelines Below is a list of various Diabetes-related clinical practice guidelines that were published between National Diabetes Month 2021 and […]

Top 10 Take-Home Messages for the ACC and AHA Diagnosis and Management of Aortic Disease Clinical Practice Guideline 2022

2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease The American College of Cardiology (ACC) and the American Heart Association (AHA) Joint Committee have just published their much anticipated clinical practice guideline on the Diagnosis and Management of Aortic Disease. This guideline covers everything from the basics of aortic anatomy, to in-depth discussions […]

New Clinical Guidelines & FDA Drug Approvals – October 2022

Treatment of Metastatic Colorectal Cancer Society:American Society of Clinical Oncology (ASCO) Published:October 17, 2022 Pharmacological Interventions for Adults With Obesity Society:American Gastroenterological Association (AGA) Published:October 20, 2022 Drug Allergy (2022 Update) Society:American College of Allergy, Asthma, & Immunology (ACAAI) & American Academy of Allergy, Asthma, & Immunology (AAAI) Published:October 3, 2022 Diabetes Management in Chronic […]

Top 7 Most Unusually Specific Clinical Guidelines – 2022 Edition

As most know, clinical guidelines are meant to translate the best available evidence into the best available clinical practice. The best available evidence is commonly in the form of randomized controlled trials (RCTs), and most RCTs study homogenous populations. This of course makes sense, because the trials want to be as controlled as possible and […]

Breast Cancer Awareness Month 2022 – The Latest Clinical Guidelines & FDA Approvals for Breast Cancer

Breast Cancer Awareness Month, held each year in October with the 21st dedicated to National Mammography Day 2022 designed to to improve support and screening for the disease. In this article, we will take a closer look at all of the new guidelines, therapies and innovations that have been introduced since Breast Cancer Awareness Month […]

New Clinical Guidelines & FDA Drug Approvals – September 2022

Integrative Medicine for Pain Management in Oncology Society:American Society of Clinical Oncology (ASCO) Published:September 19, 2022 Prevention & Treatment of Opportunistic Infections in HIV-Exposed & HIV-Infected Children Society:Department of Health & Human Services (DHHS) Published:September 2, 2022 Assessment & Management of Statin-Associated Muscle Symptoms (SAMS) Society:National Lipid Association (NLA) Published:September 10, 2022 Primary Sclerosing Cholangitis […]

World Heart Day 2022 – What’s New in Cardiovascular Medicine?

Today, September 29th, marks World Heart Day. A day established by the World Heart Federation (WFH) that’s dedicated to help raise awareness around cardiovascular disease around the globe each year. With a lot of new guidelines being published and updated, we’ve taken the courtesy of compiling all of the new cardiovascular disease guidelines, therapies and […]

American Gastroenterological Association’s 2022 IBS Guidelines

Pharmacological Management of IBS with Constipation & IBS with Diarrhea Guidelines The American Gastroenterological Association (AGA) 2022Pharmacological Management of IBS guidelines were published as two separate guidelines to stratify the treatment recommendations for two of the IBS subtypes: IBS with diarrhea (IBS-D) and IBS with constipation (IBS-C). The chart below details the new medication treatment options […]

NEW CLINICAL GUIDELINES & FDA APPROVALS-AUGUST 2022 ALERT

MISSED OUT ON THE LATEST CLINICAL GUIDELINE ANNOUNCEMENTS? No problem, we’ve got you covered! Here’s a list to all guidelines and FDA approvals that were published last month.  CLINICAL GUIDELINES AABB COVID-19 Convalescent Plasma AAES Adrenalectomy AAOS Management of Anterior Cruciate Ligament Injuries AAP Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks […]

Immunization Guidelines And Schedules

Select Immunization Guidelines and Schedules for All Ages in Clinical Practice August is National Immunization Awareness Month!  Emphasizing the value and importance of vaccinations, August National Immunization Awareness Month highlights the goal of immunization for disease prevention for all ages! Prevent serious diseases with the latest immunization guidelines and schedules listed below! CLINICAL GUIDELINES CDC Childhood […]

NEW CLINICAL GUIDELINES & FDA APPROVALS – JULY 2022 ALERT

MISSED OUT ON THE LATEST CLINICAL GUIDELINE ANNOUNCEMENTS? No problem, we’ve got you covered! Here’s a list to all guidelines and FDA approvals that were published last month.  CLINICAL GUIDELINES AAP Vision and Concussion: Symptoms, Signs, Evaluation, and Treatment AGA Management of Subepithelial Lesions (SEL) Encountered During Routine Endoscopy AHA Polygenic Risk Scores for Cardiovascular […]

NEW CLINICAL GUIDELINES & FDA APPROVALS – JUNE 2022 ALERT

MISSED OUT ON THE LATEST CLINICAL GUIDELINE ANNOUNCEMENTS? No problem, we’ve got you covered! Here’s a list to all guidelines and FDA approvals that were published last month.  CLINICAL GUIDELINES AAP Sleep-Related Infant Deaths: Updated 2022 Recommendations for Reducing Infant Deaths in the Sleep Environment ACR/AAHKS Perioperative Management of Antirheumatic Medication in Patients With Rheumatic […]

Clinical Guidelines vs. Primary Studies

Why are healthcare providers encouraged to follow clinical guidelines rather than individual primary studies? Still not familiar with what clinical practice guidelines are? How they are disseminated? We’ve highlighted what they are and how they are disseminated in our previous article. As you may already know, clinical practice guidelines (CPGs) summarize the best available evidence in […]

NEW CLINICAL GUIDELINES & FDA APPROVALS – MAY 2022 ALERT

MISSED OUT ON THE LATEST CLINICAL GUIDELINE ANNOUNCEMENTS? No problem, we’ve got you covered! Here’s a list to all guidelines and FDA approvals that were published last month.  CLINICAL GUIDELINES ACMG Clinical Evaluation and Etiologic Diagnosis of Hearing Loss ASCO Exercise, Diet, and Weight Management During Cancer Treatment Systemic Therapy for Advanced Human Epidermal Growth […]

Clinical Guidelines Explained

Clinical Guidelines: What are they & how are they disseminated? Clinical practices that are based on graded research findings are more reliable than that based on an “expert opinion”. So, more focus should be directed toward identifying and understanding these graded research findings called guidelines. Guidelines, also called clinical practice guidelines (CPG), are documents containing […]

NEW CLINICAL GUIDELINES & FDA APPROVALS – APRIL 2022 ALERT

MISSED OUT ON THE LATEST CLINICAL GUIDELINE ANNOUNCEMENTS? No problem, we’ve got you covered! Here’s a list to all guidelines and FDA approvals that were published last month.  CLINICAL GUIDELINES ACC/AHA/HFSA Management of Heart Failure (2022 Update) ASCO Use of Immune Checkpoint Inhibitor Pembrolizumab in the Treatment of High-Risk, Early-Stage Triple-Negative Breast Cancer Biomarkers for […]

NEW CLINICAL GUIDELINES & FDA APPROVALS – MARCH 2022 ALERT

MISSED OUT ON THE LATEST CLINICAL GUIDELINE ANNOUNCEMENTS? No problem, we’ve got you covered! Here’s a list to all guidelines and FDA approvals that were published last month.  CLINICAL GUIDELINES IDSATreatment of ExtendedSpectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTRP. aeruginosa) WHOAbortion Care ACGManagement of Anticoagulants and Antiplatelets […]