In this post, we will be taking a closer look at some of the most popular OBGYN-related articles recently published across medical journals.
Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review
- Obstetrics & Gynecology
- June 2024
- The researchers reviewed the efficacy and safety of magnesium sulfate as a fetal neuroprotective agent for individuals at risk of preterm birth. Their findings indicate that the administration of magnesium sulfate for preterm fetal neuroprotection significantly decreases the incidence of cerebral palsy in children.
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Preliminary Efficacy of Topical Sildenafil Cream for the Treatment of Female Sexual Arousal Disorder: A Randomized Controlled Trial
- Obstetrics & Gynecology
- June 2024
- The researchers evaluated the effectiveness of a 3.6% topical sildenafil cream in healthy premenopausal women with female arousal disorder. The results showed that the topical sildenafil cream significantly improved outcomes in women with female arousal disorder, particularly in those without concomitant orgasmic dysfunction.
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Amniocentesis in pregnancies at or beyond 24 weeks: An international multicenter study
- American Journal of Obstetrics & Gynecology
- June 2024
- The researchers evaluated the indications, diagnostic yield, safety, and maternal and fetal outcomes related to amniocentesis procedures performed at or after 24 weeks of gestation. Their findings revealed that late amniocentesis, particularly in pregnancies complicated by multiple congenital anomalies, demonstrated a high diagnostic yield and a low complication rate, highlighting its significant clinical value.
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Role of gestational age at time of placental laser surgery in outcomes of twin-to-twin transfusion syndrome
- Ultrasound in Obstetrics & Gynecology
- May 2024
- The aim of this study is to analyze the survival rates and other related morbidities following fetal laser photocoagulation (FLP) at different gestational ages. The findings indicate that FLP performed at earlier gestational ages is linked to decreased overall survival rates. This is primarily due to the increased risk of donor intrauterine fetal demise (IUFD), rather than differences in preterm premature rupture of membranes (PPROM) or preterm delivery (PTD).
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Impact of low-dose aspirin exposure on obstetrical outcomes: a meta-analysis
- Journal of Psychosomatic Obstetrics & Gynecology
- May 2024
- The aim of this study is to evaluate the effects of low-dose aspirin (LDA) on obstetrical outcomes by conducting a meta-analysis of placebo-controlled randomized controlled trials (RCTs). The results of the analysis indicate that LDA has a significant positive impact on neonatal outcomes in pregnant women who are at high risk of developing preeclampsia (PE), without increasing the risk of placental abruption.
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The correlation between menstrual characteristics and fertility in women of reproductive age: a systematic review and meta-analysis
- Fertility and Sterility
- June 2024
- The aim of this study is to investigate the relationship between menstrual characteristics and fertility in women of reproductive age. Research suggests that both short and long menstrual cycle lengths can impact women’s likelihood of conceiving spontaneously. Additionally, a late age at menarche and a short duration of menstrual bleeding have been associated with reduced fertility in women of reproductive age.
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Long-term follow-up of efficacy and safety of selinexor maintenance treatment in patients with TP53wt advanced or recurrent endometrial cancer: A subgroup analysis of the ENGOT-EN5/GOG-3055/SIENDO study
- Gynecologic Oncology
- June 2024
- The objective of this study is to evaluate the extended efficacy and safety of selinexor maintenance therapy in adults with TP53 wild-type (TP53wt) stage IV or recurrent endometrial cancer (EC) who have attained partial remission (PR) or complete remission (CR) following chemotherapy. The results of this study indicate that selinexor maintenance therapy shows a favorable efficacy signal and is well-tolerated in the targeted subgroup of patients with TP53wt EC who have achieved a PR or CR post-chemotherapy.
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Seeking financial and practical support in an abortion-hostile state: Analysis of abortion fund data in Kentucky, 2014–2021
- Perspectives on Sexual and Reproductive Health
- June 2024
- Philanthropic funds play a crucial role in facilitating access to healthcare in the United States by offering both financial and practical support. However, there is a lack of understanding regarding the individuals who utilize these vital services. In this study, researchers examined data from a fund in Kentucky to identify the demographics of fund callers. The analysis revealed that compared to state data, the Kentucky Health Justice Network (KHJN) supported a larger proportion of young individuals, people of color, and individuals at later stages of pregnancy.
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The association between uterine fibroid number and size and risk of preterm birth
- American Journal of Obstetrics and Gynecology, MFM
- June 2024
- The relationship between uterine fibroids and preterm birth is well-established, however, there is limited data on whether specific characteristics of fibroids, such as number and size, can influence this risk. Findings from this extensive cohort indicate that the number and size of fibroids are indeed linked to preterm birth and can affect the severity of the condition. A higher number and larger size of fibroids are associated with an increased risk of earlier preterm birth compared to individuals without fibroids.
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There you have it – a look at some of the most popular OBGYN articles recently released. Sign up for alerts and stay informed on the latest published guidelines and articles.
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