Guideline Central Blog

Guidelines Timeline - AAO Dry Eye Syndrome

Comparing the AAO Dry Eye Syndrome Preferred Practice Pattern – Guidelines Timeline

The American Academy of Ophthalmology (AAO) is the largest association of eye physicians and surgeons globally. Their mission is to protect vision and enhance quality of life by establishing the benchmarks for ophthalmic education and championing the interests of patients and the general public.   AAO regularly releases Preferred Practice Pattern® guidelines (PPP) aimed at defining […]

Guidelines Side-By-Side Bariatric Surgery

Comparing Bariatric Surgery Guidelines – Guidelines Side-By-Side

Affecting more than one-third of adults in the US, obesity remains a pressing health challenge for both providers and patients, conferring significant risk for comorbidities such as type 2 diabetes, obstructive sleep apnea, and cardiovascular disease. While lifestyle modifications and medical therapies, including anti-obesity medications (AOM), can be effective for some, they often fall short […]

Dapagliflozin (Farxiga/AZ) – Guidelines+ Monographs (August 2024 Edition)

In this edition of our Guidelines Monographs Series, we will be taking a look at AstraZeneca’s medication dapagliflozin, brand name Farxiga. Initially approved in 2014, Farxiga is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, provided to individuals with diabetes, heart disease, or kidney disease to improve their outcomes. This Guidelines+ Monograph will take a deeper dive […]

Guidelines+ Trials Spotlight - ITRAILBLAZER-ALZ 2

TRAILBLAZER-ALZ 2 Topline Results for the Treatment of Alzheimer’s Disease – Guidelines+ Trials Spotlight

On July 2, 2024, the US Food and Drug Administration (FDA) granted approval for Eli Lilly’s Kisunla (donanemab-azbt) injection for the treatment of Alzheimer’s disease. This treatment is recommended for patients in the early stages of the disease, specifically those with mild cognitive impairment or mild dementia, as demonstrated in the clinical trials. Kisunla marks […]

What's Changed & Predictions Hyperlipidemia

Pharmacological Management for Hyperlipidemia – What’s Changed Since+ Predictions

High cholesterol, also known as hyperlipidemia, affects millions of individuals in the United States (US). This condition can lead to serious health issues, such as an increased risk of heart disease and stroke. Globally, approximately one-third of cases of ischaemic heart disease are linked to high cholesterol levels. Elevated total cholesterol is a significant contributor […]

Guidelines Spotlight Immunization Schedules for Adults and Children

Immunization Schedules for Adults and Children – Guidelines Spotlight (National Immunization Awareness Month)

As we prepare for the National Immunization Awareness Month 2024 and upcoming autumn season, we will be conducting a thorough review of the United States Immunization Schedules for both Adults and Children. These crucial recommendations are released annually by the Centers for Disease Control and Prevention (CDC). They offer essential guidance on the recommended schedules […]

Guidelines + Journal Rundown Sleep Medicine

Top Sleep Medicine Articles – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular sleep medicine-related articles recently published across medical journals. Longer-term effect of physical activity intervention on sleep quality: a secondary analysis of cluster randomized controlled trial Delayed school start time is associated with better sleep, mental health, and life satisfaction […]

Healthcare News & Research - August 2024

Healthcare News & Research – August 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Aspirin Use and Incidence of Colorectal Cancer According to Lifestyle Risk Study Details | Source Impact of Inflammation on Cognitive Function in Patients With Highly Inflammatory Rheumatoid Arthritis […]

What's Changed Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) – What’s Changed?

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammation primarily affecting the synovial joints. This condition arises from an aberrant immune response targeting the synovium, leading to persistent inflammation, joint damage, and potential systemic manifestations. If left untreated, RA can cause significant damage to the joints and surrounding tissues, potentially leading to […]

AAN’s Migraine Prevention Guideline is Now Open for Public Comment

The American Academy of Neurology (AAN) has announced that their latest guideline, “Pharmacologic Treatment for Migraine Prevention in Adults Practice Guideline Update: Report of the AAN Guidelines Subcommittee,” is now open for public comment. This practice guideline offers updated evidence-based conclusions and recommendations on the use of pharmacologic migraine prevention in adults. The primary objective […]

Guidelines Timeline - AGS Beers Criteria

Comparing the American Geriatrics Society (AGS) Beers Criteria – Guidelines Timeline

The American Geriatrics Society (AGS) Beers Criteria® for Potentially Inappropriate Medication (PIM) Use in Older Adults is a widely recognized and utilized tool in the healthcare community. The AGS Beers Criteria is regularly updated every 3-4 years to ensure its relevance and accuracy in guiding healthcare professionals in prescribing medications for individuals aged 65 and […]

Guidelines Rundown - Breastfeeding

Breastfeeding – Guidelines Rundown (National Breastfeeding Month 2024)

Our Guidelines Rundown Series continues with a new article that delves into the topic of breastfeeding in support of National Breastfeeding Month 2024. To provide guidance and clinical decision-making support on the matter, the Academy of Breastfeeding Medicine has published a comprehensive set of guidelines that address various aspects of breastfeeding, such as nutrition, supplements, […]

What's Changed & Predictions Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy – What’s Changed Since+ Predictions Series

Duchenne Muscular Dystrophy (DMD) is a severe inherited neuromuscular disorder caused by mutations in the dystrophin gene. It leads to progressive muscle wasting and irreversible functional decline. Primarily affecting males due to X-linked recessive inheritance, DMD can also rarely affect females. Symptoms include gradual muscle atrophy and fibrous tissue replacement in skeletal and cardiac muscles. […]

Guidelines + Trials Rundown: RSV Immunization in Adults

RSV Immunization in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on respiratory syncytial virus (RSV) immunization in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for RSV vaccinations, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject […]

Guidelines + Trials Rundown Multiple Myeloma

Multiple Myeloma in Adults – Guidelines+ Trials Rundown

In the latest edition of our Guidelines+ Trials Rundown Series, we delve into the most recent research and clinical trials focusing on multiple myeloma (MM) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for MM, specifically targeting adults in the United States. Please note that the dates […]

What's Changed & Predictions Thyroid Eye Disease (TED)

Thyroid Eye Disease (TED) – What’s Changed Since+ Predictions

Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex immune-mediated disorder characterized by the aberrant proliferation of orbital fibroblasts, adipogenesis, glycosaminoglycan and mucin deposition. This connective tissue remodeling results in edematous, fibrotic adipose tissue and inflammation within the orbit and underlies the consequential classic presentation of proptosis, where the eyes appear pushed […]

Guidelines Side-By-Side Obesity Rx

Anti-Obesity Medications – Guidelines Side-By-Side

Obesity remains a pervasive health challenge affecting a significant portion of the population worldwide, with implications extending beyond physical appearance to encompass profound metabolic and cardiovascular risks. As medical understanding evolves, the focus on effective weight management strategies has intensified, supported by advancements in pharmacotherapy.  As recommendations and anti-obesity medications (AOM) pharmacotherapies evolve, understanding the […]

Upcoming FDA Approvals & Decisions

Upcoming FDA Decisions – August 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines + Journal Rundown: Primary Care & Family Practice

Top Primary Care & Family Medicine: Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular primary care/family medicine-related articles recently published across medical journals. Morbidity and Mortality of Hospital-Onset SARS-CoV-2 Infections Due to Omicron Versus Prior Variants: A Propensity-Matched Analysis Is Prediabetes Overdiagnosed? Yes: A Patient-Epidemiologist’s Experience Is Prediabetes Overdiagnosed? No: A Clinician’s Perspective […]

What's Changed & Predictions Treatment of Patients With Schizophrenia

Treatment of Patients With Schizophrenia – What’s Changed Since+ Predictions Series

Among the top 10 causes of disability worldwide, schizophrenia’s relatively low prevalence is starkly contrasted by its profound impact on functional capacity and quality of life. With the National Institute of Mental Health estimating its prevalence in the US to range between 0.25% and 0.64%, schizophrenia is a disproportionately significant contributor to the global burden […]

Guidelines+ Trials Spotlight - Hidradenitis Suppurativa

Hidradenitis Suppurativa in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on hidradenitis suppurativa (HS) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for HS, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This […]

WHO Int'l Guidelines

The World Health Organization (WHO) – Guidelines International Series

In the latest installment of our Guidelines International Series, we will be delving into the latest guidelines from the World Health Organization (WHO). Established in 1948, WHO is a specialized agency of the United Nations (UN) that facilitates collaboration between nations, partners, and individuals to advance global health, ensure global security, and support marginalized populations. […]

Anesthesiology: Guidelines + Journals Rundown

Anesthesiology – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular anesthesiology-related articles recently published across medical journals. Increasing Sweep Gas Flow Reduces Respiratory Drive and Dyspnea in Nonintubated Venoarterial Extracorporeal Membrane Oxygenation Patients: A Pilot Study Postoperative Delirium and the Older Adult: Untangling the Confusion Failed spinal anesthesia for […]