Guideline Central Blog

Upcoming FDA Approvals & Decisions - July 2024

Upcoming FDA Decisions – July 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

Guidelines + Trials Rundown - Juvenile Arthritis

Advances in Juvenile Arthritis – Guidelines+ Trials Rundown

We’re going to take a look at the ongoing studies and clinical trials specific to juvenile arthritis. The below list was curated by assessing the ongoing Phase 3 trials for juvenile arthritis that are based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that have […]

Guidelines Spotlight - Melanoma & Gynecologic Cancer

SITC May 2024 Guidelines Updates for Melanoma & Gynecologic Cancer – Guidelines Spotlight

The Society for Immunotherapy of Cancer (SITC) recently released focused updates to two of its clinical practice guidelines. This edition of our Guidelines Spotlight series will examine the key changes that you need to be aware of.  Immunotherapy for the Treatment of Gynecologic Cancer Version 1.1 – Updated on May 24, 2024 Guideline Update Comments: […]

Guidelines Side-By-Side Migraine & Headache

A Comparative Analysis of Migraine & Headache Management Guidelines – National Migraine & Headache Awareness Month

National Migraine and Headache Awareness Month, observed in June, is an annual event that highlights the importance of utilizing evidence-based strategies when crafting patient-centered treatment plans for individuals grappling with headaches and migraines. With headaches ranking the 5th most common reason for emergency department visits, it is no surprise that the CDC estimates migraine disorder […]

ISTH 2024 Recap

ISTH 2024 Conference Recap – Venous Thromboembolism (VTE)

The International Society on Thrombosis and Haemostasis held its annual conference (ISTH 2024) in Bangkok, Thailand from June 22-26th. It is the premier global organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and hemostasis. During ISTH 2024, groundbreaking research on venous thromboembolism (VTE) was presented, showcasing the latest […]

Guidelines+ Trials Spotlight - Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA

Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA – Guidelines+ Trials Spotlight

According to the American Cancer Society, bladder cancer accounts for approximately 4% of all cancers in the United States, making it the fourth most common cancer in men and less common in women. The likelihood of men developing bladder cancer in their lifetime is about 1 in 28, while for women, the chance is about […]

Guidelines Spotlight - Epilepsy in Women

Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication – Guidelines Spotlight

A focused guideline update “Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After in Utero Exposure to Antiseizure Medication” was released by the American Academy of Neurology (AAN), the American Epilepsy Society (AES), and the Society for Maternal-Fetal Medicine (SMFM) on May 15, 2024. The new guideline updates the previous 2009 guideline for “Management Issues for Women with […]

Guidelines Side-By-Side IBS

Comparing AGA and ACG Guidelines for Irritable Bowel Syndrome (IBS) – Guidelines Side-By-Side

This week’s Guidelines Side-By-Side Series will compare the irritable bowel syndrome (IBS) guidelines from the two prominent GI-related associations in the United States – AGA and ACG. Below is an overview of the three guidelines that will be compared side-by-side. The AGA guidelines, while technically two separate documents, were published together at the same time. […]

Guidelines+ Journal Rundown Orthopedics

Top Orthopedics and Sports Medicine Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular orthopedics and sports medicine-related articles recently published across medical journals. Beneficial effects of exercise, testosterone, vitamin D, calcium and protein in older men-A randomized clinical trial Activity-Dependent Compensation at the Hip and Ankle at 8 Years After the Reconstruction […]

Guidelines+ Trials Rundown - Gout

Gout in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to gout in adults. The below list was curated by assessing the ongoing Phase 3 trials for gout, specific for adults, and based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that […]

SVSVAM 2024 Recap

VAM24 Conference Recap – The Latest Research on Aortic Disease

The 2024 Vascular Annual Meeting (VAM24) took place from June 19-22 in Chicago, Illinois, serving as the Society of Vascular Surgery’s (SVS) premier event. This meeting provided a plethora of valuable scientific content tailored to meet the needs of every member of the vascular care team. A key focus of VAM24 was aortic disease, encompassing […]

Upadacitinib (Rinvoq / AbbVie) and Current Clinical Guidelines – Guidelines+ Monographs

In this edition of our Guidelines+ Monographs Series, we will be taking a look at AbbVie’s medication Upadacitinib, brand name Rinvoq. Initially approved in 2019 Rinvoq is a Janus kinase (JAK) inhibitor used to treat a variety of conditions, including rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn’s disease, ankylosing spondylitis, and non-radiographic axial […]

Guidelines Timeline - Heart Failure with Reduced Ejection Fraction (HFrEF)

Comparing ACC Expert Consensus Pathways for Heart Failure with Reduced Ejection Fraction (HFrEF) – Guidelines Timelines

The American College of Cardiology (ACC), in collaboration with the American Heart Association (AHA), is renowned for its extensive publication of cardiology-related clinical practice guidelines. Alongside these guidelines, the ACC also produces Expert Consensus Decision Pathways (ECDPs), which are consensus-based documents aimed at providing valuable insights and recommendations in the field of cardiology. In this […]

Guidelines Rundown Multiple Myeloma

What’s New in Multiple Myeloma Guidelines – Guidelines Rundown

Multiple Myeloma, also known as Myeloma or Plasma Cell Myeloma, is a type of cancer that affects plasma cells, which are responsible for producing antibodies to protect against infections. This disease can present in various ways, ranging from a slow-developing form with minimal protein abnormalities and few malignant cells to a rapidly progressing and life-threatening […]

What's Changed & Predictions Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis Guidelines – What’s Changed Since+ Guidelines Prediction Series

EoE (eosinophilic esophagitis) is a chronic, immune-mediated condition characterized by mucosal inflammation and esophageal dysfunction as the result of an eosinophilic-predominant immunogenic reaction. EoE, with onset typically secondary to genetic predisposition or antigen-triggered in etiology, results in damage to the esophagus that symptomatically can present as dysphagia, odynophagia, episodes of choking episodes, or can be […]

Guidelines Spotlight - Survivorship Care for People Affected by Advanced or Metastatic Cancer

Survivorship Care for People Affected by Advanced or Metastatic Cancer – Guideline Spotlight

The Multinational Association for Supportive Care in Cancer and the American Society of Clinical Oncology (MASCC-ASCO) have recently published new guidelines entitled “Survivorship Care for Individuals Affected by Advanced or Metastatic Cancer,” on April 29, 2024. These guidelines provide comprehensive and evidence-based recommendations intended to improve the quality of life and optimize the outcomes for […]

Guidelines+ Journal Rundown Pulmonology

Top Pulmonology Articles June 2024 – Guidelines+ Journals

In this post, we will be taking a closer look at some of the most popular pulmonology-related articles recently published across medical journals. Remission in asthma Electrocardiographic Abnormalities and Their Association with Outcomes in Randomized Clinical Trials of Pulmonary Arterial Hypertension DLco and echocardiographic parameters in identifying mild pulmonary hypertension in the EUSTAR cohort of […]

Healthcare News & Research - June 2024

Healthcare News & Research – June 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Regular use of fish oil supplements and course of cardiovascular diseases: prospective cohort study Study Details | Source A Gram-negative-selective antibiotic that spares the gut microbiome Study Details […]

Clinical Guidelines Implementation Strategy - Step 6 & 7: Measure & Evaluate, Change, Optimize & Repeat

Guideline Implementation Series: Final Steps (6-7) – Measure and Evaluate Change, Optimize, and Rinse and Repeat!

At this point you’ve not only planned your implementation initiative as discussed in our previous article, but you’ve also begun to actually implement it. A very critical (and often overlooked) step is to measure and evaluate your change, with a goal of optimization and iterative refinement and improvements. Also, to communicate your findings internally in […]

Guidelines Rundown Hepatitis

Hepatitis – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article focusing on hepatitis. There are many current guidelines on hepatitis, published from a dozen different medical societies. These guidelines encompass recommendations on hepatitis B and hepatitis C, as well as their impact on individuals with chronic kidney disease, cancer, and pregnancy. Let’s now explore the list […]

USPSTF Announces Proposed Osteoporosis Screening Recommendations

The United States Preventive Services Task Force (USPSTF) has recently unveiled a draft recommendation statement regarding Osteoporosis Screening, which was published online here on June 11, 2024. In their latest recommendations for osteoporosis screening, the USPSTF proposed the following: These updated recommendations closely align with the screening guidelines established in 2018 for the prevention of […]

Guidelines+ Journals Rundown Gastroenterology

Most Popular Gastroenterology Publications June 2024 – Guidelines+ Journals Rundown

In this post, we will be taking a closer look at some of the most popular gastroenterology-related articles recently published across medical journals. Mechanisms of metastatic colorectal cancer A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial Mechanisms and management […]

ISTH 2024 Preview

ISTH 2024 Conference Preview – Venous Thromboembolism (VTE)

ISTH 2024 marks the 32nd Congress of the esteemed International Society on Thrombosis and Haemostasis (ISTH), set to take place in Bangkok, Thailand from June 22-26th. As the premier global organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and hemostasis, ISTH brings together over 7,000 clinicians, researchers, and […]

Guidelines+ Trials Spotlight - Produce

Food is Medicine & Produce Prescriptions – Guidelines+ Trials Spotlight

Nutrition plays a crucial role in maintaining overall health and well-being. A study from The Lancet revealed that poor diet is responsible for one in five deaths globally, contributing to a variety of chronic diseases such as cardiovascular diseases, cancer, and type 2 diabetes. Unfortunately, individuals with lower incomes, those residing in rural areas, and […]

Guidelines+ Trials Rundown - Celiac Disease

Celiac Disease in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to celiac disease in adults. The following list has been curated by evaluating the current Phase 2 and 3 clinical trials for celiac disease in adults conducted in the United States. Please note that the dates provided are approximate and may be […]