In this post, we will be taking a closer look at some of the most popular primary care/family medicine-related articles recently published across medical journals.

Morbidity and Mortality of Hospital-Onset SARS-CoV-2 Infections Due to Omicron Versus Prior Variants: A Propensity-Matched Analysis

  • Annals of Internal Medicine
  • July 2024
  • Many hospitals have reduced their efforts to prevent nosocomial SARS-CoV-2 infections due to the significant decrease in morbidity and mortality rates among the general population. However, there is limited information available regarding the morbidity and mortality rates of nosocomial SARS-CoV-2 infections among hospitalized patients during the Omicron era.
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Is Prediabetes Overdiagnosed? Yes: A Patient-Epidemiologist’s Experience

  • Annals of Family Medicine
  • May/June 2024
  • I recently received a diagnosis of prediabetes due to slightly elevated blood sugar levels and no other risk factors. In order to alleviate my confusion and anxiety, I utilized my background in epidemiology and health services research to thoroughly review the scientific literature. After careful analysis, I have come to the conclusion that both myself and many others may be receiving unnecessary diagnoses.
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Is Prediabetes Overdiagnosed? No: A Clinician’s Perspective

  • Annals of Family Medicine
  • May/June 2024
  • Prediabetes, frequently a precursor to more serious conditions such as type 2 diabetes and cardiovascular disease, is a critical stage for intervention in primary care. Despite concerns that it may be overdiagnosed, prediabetes can actually serve as a warning sign of metabolic syndrome, presenting a valuable opportunity for prompt and efficient treatment.
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Povidone Iodine vs Chlorhexidine Gluconate in Alcohol for Preoperative Skin Antisepsis: A Randomized Clinical Trial

  • JAMA
  • June 2024
  • Preoperative skin antisepsis is a well-established procedure aimed at preventing surgical site infections (SSIs). However, there is ongoing debate regarding the choice of antiseptic agent, specifically between povidone iodine and chlorhexidine gluconate.
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Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts

  • JAMA Network Open
  • June 2024
  • One out of every three adults in the United States utilizes multivitamins (MV), often with the primary goal of preventing disease. In 2022, the US Preventive Services Task Force conducted a review of data regarding MV supplementation and mortality from randomized clinical trials. The findings revealed insufficient evidence to determine the benefits or potential harms of MV supplementation. This lack of conclusive evidence can be attributed, in part, to the limited follow-up time and external validity of the studies.
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Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity

  • JAMA Internal Medicine
  • July 2024
  • While tirzepatide and semaglutide have demonstrated weight reduction benefits in randomized clinical trials, there is currently a lack of data from direct comparisons in populations with overweight or obesity.
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Effectiveness and cost-effectiveness of an individualised, progressive walking and education intervention for the prevention of low back pain recurrence in Australia (WalkBack): a randomised controlled trial

  • The Lancet
  • July 2024
  • The objective was to explore the clinical effectiveness and cost-effectiveness of an individualized, progressive walking and education intervention aimed at preventing the recurrence of low back pain.
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Effect of Relative Protein Intake on Hypertension and Mediating Role of Physical Fitness and Circulating Fatty Acids: A Mendelian Randomization Study

  • Mayo Clinic Proceedings
  • July 2024
  • The objective of this study is to examine the impact of protein intake on hypertension and its associated mediating pathways.
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Has mortality in the United States returned to pre-pandemic levels? An analysis of provisional 2023 data

  • Journal of Internal Medicine
  • June 2024
  • The COVID-19 pandemic, which began in 2020, has led to an increase in overall mortality rates in 2020 and subsequent years. It is currently unclear whether all-cause mortality rates will continue to be higher in 2023 compared to pre-pandemic levels.
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Efficacy and Safety of Donidalorsen for Hereditary Angioedema

  • NEJM Primary Care/Hospitalist
  • June 2024
  • Hereditary angioedema is a rare disorder characterized by episodic, potentially life-threatening swelling caused by dysregulation of the kallikrein-kinin system. Long-term prophylaxis can help stabilize this system. Donidalorsen, an antisense oligonucleotide, is specifically designed to reduce prekallikrein expression, offering a promising treatment option for individuals with this condition.
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There you have it – a look at some of the most popular primary care/family medicine articles recently released. Sign up for alerts and stay informed on the latest published guidelines and articles.

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