TNM Staging for Renal Cell Carcinoma

Provides information about the severity of renal cell cancer based on tumor, lymph node, and metastasis characteristics.

Primary Tumor (T)

Primary tumor cannot be assessed No evidence of primary tumor Organ confined, ≤4 cm Organ confined, 4-7 cm Organ confined, 7-10 cm Organ confined, >10 cm Perinephric tissue, renal sinus, or renal vein Vena cava below the diaphragm Vena cava above diaphragm or into wall of vena cava at any level Beyond Gerota's fascia or directly into adrenal gland

Regional Lymph Nodes (N)

Regional nodes cannot be assessed No regional lymph node metastasis Metastasis in a single regional lymph node Metastasis in more than one regional lymph node

Distant Metastasis (M)

Distant metastasis cannot be assessed No distant metastasis Distant metastasis

Interpretation

Source: American Joint Committee on Cancer (AJCC). AJCC Cancer Staging Manual. 8th edition. New York: Springer; 2017.

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