Guideline Central Blog

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Upcoming FDA Approvals & Decisions - June 2024

Upcoming FDA Decisions – June 2024

The Food and Drug Administration (FDA) protects public health by guaranteeing the safety, effectiveness, and security of pharmaceuticals and medical devices. The Prescription Drug User Fee Act (PDUFA) date marks the deadline by which the FDA must complete its review of drug applications. Occasionally, an advisory committee (AdCom) meeting is convened to assess the drug […]

What's Changed - Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) Guidelines – What’s Changed

Amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig’s disease, is a neurological disorder that impacts the motor neurons responsible for controlling voluntary muscle movement and breathing, according to the National Institutes of Health (NIH). The Centers for Disease Control and Prevention (CDC) has reported that at least 16,000 Americans are affected by ALS. […]

BSH Int'l Guidelines

The British Society for Haematology – Guidelines International Series

In our first installment of our Guidelines International Series, we will be examining the British Society for Haematology (BSH). As the largest haematology organization in the United Kingdom (UK), boasting over 3,000 members worldwide, BSH is the premier membership organization for haematology professionals in the UK. BSH is dedicated to promoting excellence in the study, […]

Guidelines Rundown Multiple Sclerosis

Multiple Sclerosis – Guidelines Rundown

Our Guidelines Rundown Series continues with a new article focusing on multiple sclerosis (MS). Currently, there are limited guidelines available on MS, all of which are provided by the American Academy of Neurology. These guidelines encompass a range of topics including vaccines and immunizations, therapies, alternative medicine, as well as the assessment and management of […]

Guidelines+ Journal Rundown Urology

Urology – Guidelines+ Journals Rundown (May 2024)

In this post, we will be taking a closer look at some of the most popular urology-related articles recently published across medical journals. Current and Emerging Strategies to Curb Antibiotic-Resistant Urinary Tract Infections A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy in Patients With Microhematuria. The Safe Testing of Risk for Asymptomatic […]

Guidelines + Trials Spotlight - Enhertu Metastatic Breast Cancer

Enhertu® Metastatic Breast Cancer Trial Results DESTINY-Breast06

According to the National Institutes of Health (NIH), around 13% of women will receive a cancer diagnosis at some stage in their lives. In 2021, an estimated 3,972,256 women were living with cancer in the United States. The most prevalent cancer subtype is HR+/HER2-, with an age-adjusted rate of 90 new cases per 100,000 women, […]

Guidelines Spotlight ACP Diabetes Guidelines

New 2024 ACP Diabetes Guidelines and the Removal of DPP4s – Guidelines Spotlight

The American College of Physicians (ACP) released a new clinical guideline on April 19, 2024, for Newer Pharmacologic Treatments in Adults With Type 2 Diabetes. This guideline focused specifically on three classes of medications commonly used for patients with Type 2 Diabetes Mellitus: While the guideline is relatively short, consisting of only three key recommendations, […]

Comparing Atopic Dermatitis Guidelines Side-By-Side

Comparing Atopic Dermatitis Guidelines – Guidelines Side-By-Side Series

For this installment of our Guidelines Side-By-Side Series, we’re going to take a look at the current guidelines for atopic dermatitis (AD), commonly referred to as eczema. It is a chronic inflammatory skin condition, identified by dry, itchy skin that may release clear fluid when scratched. The National Institutes of Health (NIH) estimates that this […]

Guidelines Rundown Tuberculosis

Tuberculosis – Guidelines Rundown

Our Guidelines Rundown Series progresses with a new article focused on tuberculosis. Numerous guidelines on tuberculosis are currently available, published by nearly a dozen different medical societies and organizations. The most recent guideline, issued by the World Health Organization, stands out as it leads the global initiative to eradicate tuberculosis by advocating for universal access […]

DDW 2024 Recap

DDW2024 Conference Recap: Crohn’s Disease and Ulcerative Colitis at Digestive Disease Week

The American Gastroenterological Association’s (AGA) annual meeting was held in Washington, DC from May 18-21, 2024. Digestive Disease Week® (DDW2024) is considered the leading event for gastroenterology professionals, featuring innovative advancements, networking opportunities, and the most recent research in the field. Today, we will explore some of the fascinating research presented at the DDW2024, with […]

AAFP Blood Pressure Targets in Adults With Hypertension Guidelines Spotlight

AAFP Blood Pressure Targets in Adults With Hypertension – Guidelines Spotlight

May is High Blood Pressure Education Month. High blood pressure, also known as hypertension, is a significant controllable risk factor for stroke and heart disease. In this article, we’re going to review the 2022 Blood Pressure Targets in Adults with Hypertension guideline from the American Academy of Family Physicians (AAFP) published on November 14, 2022. […]

HRS 2024 Conference Recap

HRS2024 Conference Recap – Pulsed Field Ablation at Heart Rhythm 2024

The Heart Rhythm Society’s 2024 Annual Meeting (HRS2024) was held in Boston from May 16-19, 2024. This prestigious event showcased cutting-edge research and advancements in the fields of cardiology and electrophysiology (EP). Today, we will explore some of the fascinating research presented at the HRS2024 Annual Meeting, with a specific focus on pulsed field ablation. […]

Healthcare News & Research - May 2024

Healthcare News & Research – May 2024

Welcome to our succinct summaries of the most recent healthcare news and research. Keep yourself informed with our easily digestible updates sourced from medical media and news outlets. Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men: Individual Participant Data Meta-analyses Study Details | Source Consumption of Olive […]

Acute Migraine Guidelines + Trials Rundown

Acute Migraine Treatment in Adults – Guidelines+ Trials Rundown

Today we’re going to cover the first article in a two-part series that takes a look at the ongoing studies and clinical trials specific to management of migraine in adults, including acute migraine treatment and migraine prevention (both chronic migraine prevention and episodic migraine prevention).  For Part 1 we’ll be starting with Acute Migraine Treatment […]

Guidelines+ Trials Rundown Schizophrenia in Adults

Schizophrenia in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to management of schizophrenia in adults, including in acutely psychotic people with schizophrenia and relapse prevention. The below list was curated by assessing the ongoing Phase 3 trials for migraine treatments, specific for adults, and based in the United States. The dates […]

Menopause Guidelines Side-By-Side

Analyzing Guidelines for Menopause-Related Topics – Guidelines Side-By-Side

During Women’s Health Awareness Month, it is crucial to address menopause-related issues with informed strategies. The prevalence of vasomotor symptoms of menopause ranges from 50% to 82% among US women experiencing natural menopause. Additionally, genitourinary syndrome of menopause affects 27% to 84% of postmenopausal women. Breast cancer impacts approximately one in eight women in the […]

Clinical Guidelines Implementation Strategy - Improving Adherence

Guideline Implementation Series: Step 5 – Implementing the Strategies to Improve Adherence to the Selected Guideline Recommendations

Now that you’ve identified the barriers and prioritized specific interventions as discussed in our previous article on Step 4: Determining Interventions To Mitigate The Identified Barriers, it’s time to begin looking at actual implementation. This includes following through with the previous plans you’ve put in place, and the distribution of various resources to support your […]

Dupilumab (Dupixent) – Guidelines+ Monographs (May 2024 Edition)

This is our first post in a new series called “Guidelines+ Monographs”. In this series we provide an overview of a single medication or therapeutic agent, and then compare how it is positioned across all current guidelines that the medication is indicated for. This may be a single indication/guideline in some cases, or multiple indications […]

Guidelines Spotlight ACCAHA Peripheral Artery Disease (PAD)

New Lower Extremity Peripheral Artery Disease Guidelines 2024 – What’s Changed and Key Takeaways

The 2024 AHA/ACC Guideline on the Management of Lower Extremity Peripheral Artery Disease has been officially released today. This new guideline serves as an update to the previous “2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease,” incorporating the latest evidence to assist clinicians in providing comprehensive care for patients […]

Guidelines Rundown - Stroke Awareness Month 2024

Stroke – Guidelines Rundown (Stroke Awareness Month 2024)

In honor of Stroke Awareness Month, our ongoing Guidelines Rundown Series will be dedicated to the topic of stroke. There are a multitude of current guidelines on stroke, published from over a dozen different medical societies. These guidelines encompass strategies for prevention, management, and rehabilitation post-stroke. Below is the rundown of clinical practice guidelines on stroke: […]

Dermatology: Guidelines + Journal Rundown (May 2024)

Dermatology – Guidelines+ Journals Rundown (May 2024)

In this post, we will be taking a closer look at some of the most popular dermatology-related articles recently published across leading medical journals. Venous thromboembolism risk is lower in patients with atopic dermatitis than other immune-mediated inflammatory diseases: A retrospective, observational, comparative cohort study using US claims data Oral Minoxidil vs Topical Minoxidil for […]

Guidelines Side-By-Side Hepatocellular Carcinoma

Comparing Five Current Hepatocellular Carcinoma Clinical Guidelines – Guidelines Side-By-Side Series

For the next installment of our Guidelines Side-By-Side series, we’re going to take a look at the current guidelines for liver cancer. This article will examine how the recommendations in each guideline agree, contradict, or otherwise differ.  Our topic for today will be systemic treatment for metastatic hepatocellular carcinoma. The focus will be limited to […]

ENDO 2024 Conference Preview

ENDO 2024 Conference Preview – The Latest Developments in Diabetes

ENDO 2024, the Endocrine Society’s annual meeting will take place June 1-4 in Boston, MA.  It promises to be a cutting-edge event for professionals in the field of endocrinology. This conference will feature renowned experts and thought leaders delivering informative presentations on the latest research, treatments, and trends in endocrine disorders.  Before proceeding, if you […]

APA 2024 Conference Recap

2024 APA Annual Meeting Recap – Anxiety Disorders

The American Psychiatric Association (APA) hosted its prestigious 2024 Annual Meeting from May 4th to 8th in New York, NY. This event serves as a cornerstone for the psychiatry community, showcasing cutting-edge research and advancements in the field. Today, we will delve into some of the captivating research unveiled at the APA 2024 Annual Meeting, […]