A Randomized, Phase II/III Study of Pegylated Liposomal Doxorubicin and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin, CTEP-Supplied Bevacizumab and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin and CTEP-Supplied Bevacizumab in Platinum Resistant Ovarian Cancer

ClinicalTrials.gov processed this data on November 7, 2023. Link to the current ClinicalTrials.gov record.

Recruitment Status

ACTIVE, NOT RECRUITING (See Contacts and Locations)
Verified September 2023 by National Cancer Institute (NCI), NRG Oncology

Sponsor

National Cancer Institute (NCI)

Information Provided by (Responsible Party)

National Cancer Institute (NCI)

Clinicaltrials.gov Identifier

NCT02839707
Other Study ID Numbers: NCI-2016-01081
First Submitted: July 20, 2016
First Posted: July 21, 2016
Last Update Posted: November 8, 2023
Last Verified: September 2023
History of Changes

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Study Description

PRIMARY OBJECTIVES:

I. Estimate the probability of a dose limiting toxicity (DLT) following cycle 1 of experimental regimens (pegylated liposomal doxorubicin hydrochloride [pegylated liposomal doxorubicin] [PLD] and atezolizumab and PLD/bevacizumab and atezolizumab). (Safety lead-in) II. Estimate and compare the hazard of first progression or death (progression free survival [PFS]) of each experimental regimen relative to the reference regimen, PLD and bevacizumab. (Phase II study) III. Estimate and compare the hazard of death and the hazard of first progression or death (PFS) of the experimental regimen relative to the reference regimen. (Phase III) (24-FEB-2021)

SECONDARY OBJECTIVES:

I. Estimate and compare the probabilities of response (objective response rate [ORR], either partial or complete response) defined by Response Evaluation Criteria in Solid Tumors (RECIST) version (v)1.1 criteria on each study regimen. (Phase II study) (24-FEB-2021) II. Estimate the frequency and severity of adverse events as classified and graded with Common Terminology Criteria for Adverse Events (CTCAE) in those patients who initiate their randomly assigned study treatment. (Phase II study) (03/19/2018) III. Estimate and compare ORR in each treatment group. (Phase III study) IV. Estimate the frequency and severity of adverse events in those patients who initiate their randomly assigned study treatment. (Phase III study) V. Estimate and compare mean patient reported outcome scores (PROs) as measured by National Comprehensive Cancer Network (NCCN)-Functional Assessment of Cancer Therapy (FACT) ovarian symptom index (NFOSI)-18 disease-related symptoms (DRS). (Phase III study) VI. Estimate and compare the treatment groups on the basis of the PROs: treatment side effects (TSE), function/well-being (FWB), fatigue (Functional Assessment of Chronic Illness Therapy [FACIT]-fatigue subscale) and abdominal discomfort (FACT/Gynecologic Oncology Group [GOG]-abdominal discomfort [AD] subscale). (Phase III study) (10/16/2017)

TRANSLATIONAL SCIENCE OBJECTIVES:

I. To determine whether biomarker levels in pre-treatment tissue, and pre- or on-treatment peripheral blood, and stool specimens are associated with ORR, PFS and/or overall survival (OS).

II. Estimate pre-treatment PD-L1 expression on tumor cells measured by quantitative immunohistochemistry (IHC), and determine whether it is associated with the duration of PFS or overall survival. (Integrated Biomarker) III. Analysis of T cell receptor (TCR) repertoires by deep sequencing of peripheral blood samples. (Exploratory Biomarkers [10/16/2017]) IV. Tumor "immunogenicity" as determined by the neo-antigen landscape and characterization of the tumor microenvironment using next-generation sequencing, including but not limited to whole exome sequencing and/or RNA sequencing. (Exploratory Biomarkers [10/16/2017]) V. Microbiome analysis via stool sampling. (Exploratory Biomarkers [10/16/2017]) VI. To determine whether changes in quantitative biomarker parameters after the first 6 and 12 weeks of therapy predict ORR, PFS and/or OS.

OUTLINE: Patients will be randomized to 1 of 3 arms.

ARM I: Patients receive pegylated liposomal doxorubicin hydrochloride intravenously (IV) over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)

ARM II: Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo computed tomography (CT) on study.

ARM III: Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.

In all arms, cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for up to 2 years, and then every 6 months for up to 3 years.
Condition or Disease Intervention/Treatment
  • Fallopian Tube High Grade Serous Adenocarcinoma
  • Ovarian High Grade Serous Adenocarcinoma
  • Ovarian Seromucinous Carcinoma
  • Primary Peritoneal High Grade Serous Adenocarcinoma
  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Fallopian Tube Clear Cell Adenocarcinoma
  • Recurrent Fallopian Tube Endometrioid Adenocarcinoma
  • Recurrent Fallopian Tube Undifferentiated Carcinoma
  • Recurrent Ovarian Carcinoma
  • Recurrent Ovarian Clear Cell Adenocarcinoma
  • Recurrent Ovarian Endometrioid Adenocarcinoma
  • Recurrent Ovarian Undifferentiated Carcinoma
  • Recurrent Platinum-Resistant Fallopian Tube Carcinoma
  • Recurrent Platinum-Resistant Ovarian Carcinoma
  • Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
  • Recurrent Primary Peritoneal Carcinoma
  • Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
  • Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
  • Recurrent Primary Peritoneal Undifferentiated Carcinoma
  • Drug: Atezolizumab
  • Biological: Bevacizumab
  • Procedure: Computed Tomography
  • Drug: Pegylated Liposomal Doxorubicin Hydrochloride
  • Other: Quality-of-Life Assessment

Study Design

Study TypeInterventional
Actual Enrollment443 participants
Design AllocationRandomized
Interventional ModelParallel Assignment
MaskingNone (Open Label)
Primary PurposeTreatment
Official TitleA Randomized, Phase II/III Study of Pegylated Liposomal Doxorubicin and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin, CTEP-Supplied Bevacizumab and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin and CTEP-Supplied Bevacizumab in Platinum Resistant Ovarian Cancer
Study Start DateJune 23, 2017
Actual Primary Completion DateMay 9, 2023
Anticipated Study Completion DateSeptember 21, 2024

Groups and Cohorts

Group/ CohortIntervention/ Treatment
  • Arm I (PLD, atezolizumab)
    • Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)
  • Drug: Atezolizumab
    • Given IV
  • Procedure: Computed Tomography
    • Drug: Pegylated Liposomal Doxorubicin Hydrochloride
      • Other: Quality-of-Life Assessment
        • Arm II (PLD, bevacizumab, atezolizumab)
          • Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo CT on study.
        • Drug: Atezolizumab
          • Given IV
        • Biological: Bevacizumab
          • Procedure: Computed Tomography
            • Drug: Pegylated Liposomal Doxorubicin Hydrochloride
              • Other: Quality-of-Life Assessment
                • Arm III (PLD, bevacizumab)
                  • Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.
                • Biological: Bevacizumab
                  • Procedure: Computed Tomography
                    • Drug: Pegylated Liposomal Doxorubicin Hydrochloride
                      • Other: Quality-of-Life Assessment

                        Outcome Measures

                        Primary Outcome Measures

                        1. Incidence of dose limiting toxicities (DLT) of experimental regimens [Up to 28 days]
                          Will be graded using Common Terminology Criteria for Adverse Events (CTCAE) version (v) 4.0 (CTCAE version 5.0 will be used beginning April 1, 2018). DLT will be assessed.
                        2. Progression free survival (PFS) (Phase II) [From study enrollment to the investigator determined date of progression or death due to any cause, whichever occurs first, assessed up to 5 years]
                          Will be assessed by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 criteria and will include estimates of the hazard ratios and the corresponding confidence intervals for the experimental regimen relative to the reference regimen, as well as Kaplan-Meier estimates of the survivorship function for each treatment group.
                        3. PFS (Phase III) [From study enrollment to the investigator determined date of progression or death due to any cause, whichever occurs first, assessed up to 5 years]
                          Will be assessed by RECIST v1.1 criteria and will include estimates of the hazard ratios and the corresponding confidence intervals for the experimental regimen relative to the reference regimen, as well as Kaplan-Meier estimates of the survivorship function for each treatment group.
                        4. Overall survival (OS) (Phase III) [From study enrollment to the date of death regardless of the cause, assessed up to 5 years]
                          OS will be evaluated.

                        Secondary Outcome Measures

                        1. Objective response rate (ORR) (partial or complete response) (Phase II) [Up to 5 years]
                          Will be assessed by RECIST v1.1 criteria. Will be tabulated by treatment group, and 95% confidence intervals will be presented using Wilson's Score Method. Treatment arms will be compared using a likelihood ratio chi-square test.
                        2. ORR (partial or complete response) (Phase III) [Up to 5 years]
                          Will be assessed by RECIST v1.1. Will be tabulated by treatment group, and 95% confidence intervals will be presented using Wilson's Score Method. Treatment arms will be compared using a likelihood ratio chi-square test.
                        3. Frequency and severity of adverse events (Phase II) [Up to 5 years]
                          The maximum grade of each adverse event (AE) by system organ class and Common Toxicity Criteria (CTC) 4.0 (CTCAE version 5.0 will be used beginning April 1, 2018) specific term will be tabulated for those individuals who at least initiate study treatment. The number and percent of individuals will be tabulated by the maximum grade of their AE.
                        4. Frequency and severity of adverse events (Phase III) [Up to 5 years]
                          The maximum grade of each AE by system organ class and CTC 4.0 (CTCAE version 5.0 will be used beginning April 1, 2018) specific term will be tabulated for those individuals who at least initiate study treatment. The number and percent of individuals will be tabulated by the maximum grade of their AE.
                        5. Disease-related symptoms (Phase II) [Up to 2 years]
                          Will be assessed by the National Comprehensive Cancer Network (NCCN)- Functional Assessment of Cancer Therapy (FACT) ovarian symptom index (NFOSI)-18 disease-related symptoms (DRS). A repeated measures model will be used to estimate and compare the mean DRS-physical (P) scores for the treatment groups. Model covariates will include the patients' randomly assigned study treatment, age at enrollment onto the study, initial performance status, pre-treatment DRS-P score, assessment time and treatment-by-time interaction. The primary analyses will include only those treatments selected at the end of the phase II study and all of the patients assigned to one of these treatments during either stage 2 of the safety lead-in, phase II or phase III component of the study regardless of their compliance with the study treatment or eligibility status, provided at least one baseline (pre-treatment) and one follow-up assessment is available.
                        6. Disease-related symptoms (Phase III) [Up to 2 years]
                          Will be assessed by the NFOSI-18 DRS. A repeated measures model will be used to estimate and compare the mean DRS-P scores for the treatment groups. Model covariates will include the patients' randomly assigned study treatment, age at enrollment onto the study, initial performance status, pre-treatment DRS-P score, assessment time and treatment-by-time interaction. The primary analyses will include only those treatments selected at the end of the phase II study and all of the patients assigned to one of these treatments during either stage 2 of the safety lead-in, phase II or phase III component of the study regardless of their compliance with the study treatment or eligibility status, provided at least one baseline (pre-treatment) and one follow-up assessment is available.
                        7. Patient reported outcomes (PRO) (Phase II) [Up to 2 years]
                          Will be as measured by treatment side effects (TSE), function/well-being (FWB), fatigue and health status. Each of the other general PRO scales will be analyzed with repeated measures models. Exploratory analyses will include an assessment of the model residuals in order to evaluate the adequacy of modeling assumptions. Additional descriptive analyses will assess whether the differences in mean scores between groups vary systematically with time in a linear or quadratic fashion.
                        8. Patient reported outcomes (Phase III) [Up to 2 years]
                          Will be measured by TSE, FWB, fatigue and health status. Each of the other general PRO scales will be analyzed with repeated measures models. Exploratory analyses will include an assessment of the model residuals in order to evaluate the adequacy of modeling assumptions. Additional descriptive analyses will assess whether the differences in mean scores between groups vary systematically with time in a linear or quadratic fashion.
                        9. PD-L1 expression [Up to 5 years]
                          Will be assessed in enrolled patients using immunohistochemistry on tumors embedded in paraffin. The proportion of patients expressing PD-L1 in this patient population will be estimated. A proportional hazards model will be used to estimate the hazard of death for patients who express PD-L1 relative to those who do not express PL-D1 for each treatment group. The homogeneity of these estimated hazard ratios will then be assessed. Its association with the duration of PFS or OS will be determined.

                        Eligibility Criteria

                        Ages Eligible for Study 18 Years and Older (Adult, Older Adult)
                        Sexes Eligible for Study Female
                        Accepts Healthy Volunteers No
                        Inclusion Criteria
                        • Patients must have the psychological ability and general health that permits completion of the study requirements and required follow up
                        • Administration of study drugs (pegylated liposomal doxorubicin, bevacizumab, atezolizumab) may have an adverse effect on pregnancy and poses a risk to the human fetus, including embryo-lethality; women of child-bearing potential (WOCBP) must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and for 5 months (150 days) after the last dose of study agent; should a woman become pregnant or suspect she is pregnant while she is participating in this study, she should inform her treating physician immediately. (06/29/2017)
                        • Submission of tumor tissue is required for all patients; investigators should check with their site pathology department regarding release of biospecimens before approaching patients about participation in the trial
                        • High grade ovarian cancer, including high grade serous; clear cell; endometrioid, grade 3; and others (adenocarcinoma, not otherwise specified [NOS]; mixed epithelial carcinoma; undifferentiated carcinoma); NOTE: low grade serous, mucinous and carcinosarcoma histologies are excluded due to their different underlying genomic features and/or clinical behavior; ovarian cancer = ovarian, fallopian tube or primary peritoneal cancer; required data element: submission of pathology report
                        • Recurrent, platinum resistant ovarian cancer (defined as progression within < 6 months from completion of platinum based therapy; the date should be calculated from the last administered dose of platinum therapy)
                        • 1-2 prior regimens (including primary therapy); hormonal therapies (e.g., tamoxifen, aromatase inhibitors) will not count toward the prior regimen limit; PARP inhibitors given in the maintenance setting post response to platinum-based therapy will not count as a separate regimen from the preceding platinum-based therapy. (30-OCT-2020)
                        • Measurable disease (defined by RECIST v1.1) or evaluable disease (defined as solid and/or cystic abnormalities on radiographic imaging that do not meet RECIST 1.1 definitions for target lesions OR ascites and/or pleural effusion that has been pathologically demonstrated to be disease related in the setting of cancer antigen [CA] 125 >= 2 x upper limit of normal [ULN])
                        • Age >= 18
                        • Performance status 0, 1 or 2
                        • Absolute neutrophil count (ANC) >= 1,500/mcl (within 14 days prior to registration)
                        • Platelets >= 100,000/mcl (within 14 days prior to registration)
                        • Hemoglobin (Hgb) >= 8 g/dl (within 14 days prior to registration)
                        • Creatinine =< 1.5 x institutional upper limit of normal (ULN) (within 14 days prior to registration)
                        • Urine protein creatinine (UPC) ratio must be < 1.0 (within 14 days prior to registration); if UPC ratio >= 1, collection of 24-hour urine measurement of urine protein is recommended (24-hour urine protein level must be < 1000 mg for patient enrollment); If UPC ratio cannot be calculated because the urine protein is below the lower limit of detection of the assay this will not exclude the patient (10/22/2018) (30-OCT-2020); UPC ratio of spot urine is an estimation of the 24-hour urine protein excretion - a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm
                        • Total bilirubin =< 1.5 x ULN (patients with known Gilbert disease who have serum bilirubin level =< 3 x ULN may be enrolled) (within 14 days prior to registration)
                        • Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3 x ULN (AST and/or ALT =< 5 x ULN for patients with liver involvement) (within 14 days prior to registration)
                        • International normalized ratio (INR) and activated partial thromboplastin time (aPTT) =< 1.5 x ULN (or on stable dose of therapeutic anticoagulation, such as low-molecular-weight heparin, warfarin or rivaroxaban) (10/16/2017)
                        • Thyroid-stimulating hormone (TSH) within normal limits (Euthyroid patients on thyroid replacement therapy allowed provided TSH < ULN) (02/20/2019)
                        • The patient or legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information
                        Exclusion Criteria
                        • Patients with prior allogeneic bone marrow transplantation or prior solid organ transplantation
                        • Patients who have had systemic anticancer therapy (e.g., chemotherapy, targeted therapy including PARP inhibitors or bevacizumab) within 3 weeks prior to entering the study (30-OCT-2020)
                        • Patients who have had hormonal therapy (e.g., tamoxifen, aromatase inhibitor) within 1 week prior to entering the study
                        • Patients with prior treatment with anti-programmed cell death (PD)-1, anti- programmed cell death ligand (PD-L)1 or anti-cytotoxic T-lymphocyte-associated protein (CTLA)-4 therapeutic antibody or other similar agents (10/16/2017)
                        • Patients with prior treatment with bevacizumab (or any other anti vascular therapy, e.g., cediranib) for platinum resistant recurrence; (Note: prior bevacizumab in initial therapy and/or platinum sensitive recurrent setting is allowed) (10/16/2017)
                        • Patients with prior treatment with PLD
                        • Prior radiotherapy to the abdomen or pelvis
                        • Patients who have not recovered from adverse events to =< grade 1 (other than alopecia) due to agents administered more than 3 weeks earlier (10/16/2017); however, the following therapies are allowed:
                        • Hormone replacement therapy or oral contraceptives
                        • Herbal therapy > 1 week prior to cycle 1, day 1 (herbal therapy intended as anticancer therapy must be discontinued at least 1 week prior to cycle 1, day 1)
                        • Palliative radiotherapy for bone metastases > 2 weeks prior to cycle 1, day 1
                        • Treatment with any other investigational agent within 4 weeks prior to cycle 1, day 1
                        • Treatment with systemic immunostimulatory agents (including, but not limited to, interferon [IFN]-alpha or interleukin [IL]-2) within 6 weeks prior to cycle 1, day 1
                        • Treatment with systemic immunosuppressive medications (including, but not limited to, prednisone, cyclophosphamide, azathioprine, methotrexate, thalidomide, and anti-tumor necrosis factor [anti-TNF] agents) within 2 weeks prior to cycle 1, day 1
                        • Patients who have received acute, low dose, systemic immunosuppressant medications (e.g., a one-time dose of dexamethasone for nausea or steroids as computed tomography [CT] scan contrast premedication) may be enrolled
                        • The use of inhaled corticosteroids and mineralocorticoids (e.g., fludrocortisone) for patients with orthostatic hypotension or adrenocortical insufficiency is allowed
                        • Patients taking bisphosphonate therapy for symptomatic hypercalcemia within the past 28 days; use of bisphosphonate therapy for other reasons (e.g., bone metastasis or osteoporosis) is allowed
                        • Patients with known primary central nervous system (CNS) malignancy or symptomatic CNS metastases are excluded, with the following exceptions:
                        • Patients with asymptomatic untreated CNS disease may be enrolled, provided all of the following criteria are met:
                        • Evaluable or measurable disease outside the CNS
                        • No metastases to brain stem, midbrain, pons, medulla, cerebellum, or within 10 mm of the optic apparatus (optic nerves and chiasm)
                        • No history of intracranial hemorrhage or spinal cord hemorrhage
                        • No ongoing requirement for dexamethasone for CNS disease; patients on a stable dose of anticonvulsants are permitted
                        • No neurosurgical resection or brain biopsy within 28 days prior to cycle 1, day 1
                        • Patients with asymptomatic treated CNS metastases may be enrolled, provided all the criteria listed above are met as well as the following:
                        • Radiographic demonstration of improvement upon the completion of CNS directed therapy and no evidence of interim progression between the completion of CNS directed therapy and the screening radiographic study
                        • No stereotactic radiation or whole-brain radiation within 28 days prior to cycle 1, day 1
                        • Screening CNS radiographic study >= 4 weeks from completion of radiotherapy and >= 2 weeks from discontinuation of corticosteroids
                        • Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies
                        • History of severe allergic, anaphylactic, or other hypersensitivity reactions to chimeric or humanized antibodies or fusion proteins
                        • Patients requiring treatment with a receptor activator of nuclear factor kappa-B ligand (RANKL) inhibitor (e.g. denosumab) who cannot discontinue it before treatment with atezolizumab
                        • Known clinically significant liver disease, including active viral, alcoholic, or other hepatitis; cirrhosis; fatty liver; and inherited liver disease
                        • Patients with past or resolved hepatitis B infection (defined as having a negative hepatitis B surface antigen [HBsAg] test and a positive anti-HBc [antibody to hepatitis B core antigen] antibody test) are eligible
                        • Patients positive for hepatitis C virus (HCV) antibody are eligible only if polymerase chain reaction (PCR) is negative for HCV ribonucleic acid (RNA)
                        • History or risk of autoimmune disease, including but not limited to systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, vascular thrombosis associated with antiphospholipid syndrome, Wegener's granulomatosis, Sjogren's syndrome, Guillain-Barre syndrome, multiple sclerosis, autoimmune thyroid disease, vasculitis, or glomerulonephritis (02/20/2019)
                        • Patients with a history of autoimmune hypothyroidism on a stable dose of thyroid replacement hormone are eligible
                        • Patients with controlled type 1 diabetes mellitus on a stable insulin regimen, or type 2 diabetes mellitus are eligible
                        • Patients with eczema, psoriasis, lichen simplex chronicus or vitiligo with dermatologic manifestations only (e.g., patients with psoriatic arthritis would be excluded) are permitted provided that they meet the following conditions:
                        • Patients with psoriasis must have a baseline ophthalmologic exam to rule out ocular manifestations
                        • Rash must cover less than 10% of body surface area (BSA)
                        • Disease is well controlled at baseline and only requiring low potency topical steroids (e.g., hydrocortisone 2.5%, hydrocortisone butyrate 0.1%, fluocinolone 0.01%, desonide 0.05%, alclometasone dipropionate 0.05%)
                        • No acute exacerbations of underlying condition within the last 12 months (not requiring psoralen plus ultraviolet A radiation [PUVA], methotrexate, retinoids, biologic agents, oral calcineurin inhibitors; high potency or oral steroids)
                        • History of idiopathic pulmonary fibrosis, pneumonitis (including drug induced), organizing pneumonia (i.e., bronchiolitis obliterans, cryptogenic organizing pneumonia, etc.), or evidence of active pneumonitis on screening chest computed tomography (CT) scan; history of radiation pneumonitis in the radiation field (fibrosis) is permitted
                        • Patients with active tuberculosis (TB) are excluded
                        • Severe infections within 4 weeks prior to cycle 1, day 1, including but not limited to hospitalization for complications of infection, bacteremia, or severe pneumonia
                        • Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1
                        • Received oral or intravenous (IV) antibiotics within 2 weeks prior to cycle 1, day 1; patients receiving prophylactic antibiotics (e.g., for prevention of a urinary tract infection or chronic obstructive pulmonary disease) are eligible
                        • Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study
                        • Administration of a live, attenuated vaccine within 4 weeks before cycle 1, day 1 or anticipation that such a live, attenuated vaccine will be required during the study and up to 5 months after the last dose of atezolizumab (06/29/2017)
                        • Influenza vaccination should be given during influenza season only (approximately October to March); patients must not receive live, attenuated influenza vaccine within 4 weeks prior to cycle 1, day 1 or at any time during the study
                        • Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
                        • Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial (08-JAN-2021)
                        • Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 3 years, with the exception of those with a negligible risk of metastases or death, such as carcinoma in situ of the breast or cervix
                        • Severe, active co-morbidity defined as follows:
                        • Current (within 28 days of cycle 1, day 1) signs and/or symptoms of bowel obstruction
                        • Patients who require parental hydration and/or nutrition
                        • Patients who require drainage gastrostomy tube
                        • Evidence of bleeding diathesis or clinically significant coagulopathy
                        • Serious, non-healing or dehiscing wound, active ulcer or untreated bone fracture
                        • History of hemoptysis (>= 1/2 teaspoon of bright red blood per episode) within 1 month of study enrollment
                        • Significant cardiovascular or cerebrovascular disease including:
                        • Uncontrolled hypertension (systolic blood pressure [SBP] >= 150 and/or diastolic blood pressure [DBP] >= 90)
                        • History of myocardial infarction within 6 months
                        • Unstable angina
                        • New York Heart Association functional classification II, III or IV
                        • Baseline ejection fraction =< 50% as assessed by echocardiogram or multi-gated acquisition (MUGA)
                        • Cerebral vascular accident (CVA) or transient ischemic attack (TIA) within 6 months
                        • Significant vascular disease (e.g., aortic aneurysm, requiring surgical repair or peripheral arterial thrombosis) within 6 months
                        • History of abdominal/pelvic or tracheoesophageal fistula or gastrointestinal perforation and/or abdominal/pelvic abscess within 6 months prior to initiation of treatment (02/20/2019)
                        • Pregnant or lactating patients

                        Contacts and Locations

                        Sponsors and Collaborators National Cancer Institute (NCI), NRG Oncology
                        NRG Oncology
                        Locations
                        • Anchorage Associates in Radiation Medicine | Anchorage, Alaska, United States, 98508
                        • Anchorage Radiation Therapy Center | Anchorage, Alaska, United States, 99504
                        • Alaska Breast Care and Surgery LLC | Anchorage, Alaska, United States, 99508
                        • Alaska Oncology and Hematology LLC | Anchorage, Alaska, United States, 99508
                        • Alaska Women's Cancer Care | Anchorage, Alaska, United States, 99508
                        • Anchorage Oncology Centre | Anchorage, Alaska, United States, 99508
                        • Katmai Oncology Group | Anchorage, Alaska, United States, 99508
                        • Providence Alaska Medical Center | Anchorage, Alaska, United States, 99508
                        • Fairbanks Memorial Hospital | Fairbanks, Alaska, United States, 99701
                        • CTCA at Western Regional Medical Center | Goodyear, Arizona, United States, 85338
                        • Kingman Regional Medical Center | Kingman, Arizona, United States, 86401
                        • Cancer Center at Saint Joseph's | Phoenix, Arizona, United States, 85004
                        • Banner University Medical Center - Tucson | Tucson, Arizona, United States, 85719
                        • Mercy Hospital Fort Smith | Fort Smith, Arkansas, United States, 72903
                        • CHI Saint Vincent Cancer Center Hot Springs | Hot Springs, Arkansas, United States, 71913
                        • University of Arkansas for Medical Sciences | Little Rock, Arkansas, United States, 72205
                        • Kaiser Permanente-Anaheim | Anaheim, California, United States, 92806
                        • Kaiser Permanente-Deer Valley Medical Center | Antioch, California, United States, 94531
                        • Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande, California, United States, 93420
                        • PCR Oncology | Arroyo Grande, California, United States, 93420
                        • Sutter Auburn Faith Hospital | Auburn, California, United States, 95602
                        • Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn, California, United States, 95603
                        • Kaiser Permanente-Baldwin Park | Baldwin Park, California, United States, 91706
                        • Kaiser Permanente-Bellflower | Bellflower, California, United States, 90706
                        • Alta Bates Summit Medical Center-Herrick Campus | Berkeley, California, United States, 94704
                        • Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank, California, United States, 91505
                        • Mills-Peninsula Medical Center | Burlingame, California, United States, 94010
                        • Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park, California, United States, 95682
                        • Mercy San Juan Medical Center | Carmichael, California, United States, 95608
                        • Eden Hospital Medical Center | Castro Valley, California, United States, 94546
                        • Community Cancer Institute | Clovis, California, United States, 93611
                        • University Oncology Associates | Clovis, California, United States, 93611
                        • John Muir Medical Center-Concord Campus | Concord, California, United States, 94520
                        • Sutter Davis Hospital | Davis, California, United States, 95616
                        • Epic Care-Dublin | Dublin, California, United States, 94568
                        • Kaiser Permanente Dublin | Dublin, California, United States, 94568
                        • Mercy Cancer Center - Elk Grove | Elk Grove, California, United States, 95758
                        • Bay Area Breast Surgeons Inc | Emeryville, California, United States, 94608
                        • Epic Care Partners in Cancer Care | Emeryville, California, United States, 94608
                        • Kaiser Permanente-Fontana | Fontana, California, United States, 92335
                        • Kaiser Permanente-Fremont | Fremont, California, United States, 94538
                        • Palo Alto Medical Foundation-Fremont | Fremont, California, United States, 94538
                        • Fresno Cancer Center | Fresno, California, United States, 93720
                        • Kaiser Permanente-Fresno | Fresno, California, United States, 93720
                        • Marin Cancer Care Inc | Greenbrae, California, United States, 94904
                        • Marin General Hospital | Greenbrae, California, United States, 94904
                        • Kaiser Permanente - Harbor City | Harbor City, California, United States, 90710
                        • Kaiser Permanente-Irvine | Irvine, California, United States, 92618
                        • Loma Linda University Medical Center | Loma Linda, California, United States, 92354
                        • Kaiser Permanente Los Angeles Medical Center | Los Angeles, California, United States, 90027
                        • Kaiser Permanente West Los Angeles | Los Angeles, California, United States, 90034
                        • Contra Costa Regional Medical Center | Martinez, California, United States, 94553-3156
                        • Memorial Medical Center | Modesto, California, United States, 95355
                        • Kaiser Permanente-Modesto | Modesto, California, United States, 95356
                        • Palo Alto Medical Foundation-Camino Division | Mountain View, California, United States, 94040
                        • Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View, California, United States, 94040
                        • Sutter Cancer Research Consortium | Novato, California, United States, 94945
                        • Alta Bates Summit Medical Center - Summit Campus | Oakland, California, United States, 94609
                        • Bay Area Tumor Institute | Oakland, California, United States, 94609
                        • Kaiser Permanente Oakland-Broadway | Oakland, California, United States, 94611
                        • Kaiser Permanente-Oakland | Oakland, California, United States, 94611
                        • Kaiser Permanente-Ontario | Ontario, California, United States, 91761
                        • UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange, California, United States, 92868
                        • Palo Alto Medical Foundation Health Care | Palo Alto, California, United States, 94301
                        • Kaiser Permanente - Panorama City | Panorama City, California, United States, 91402
                        • Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova, California, United States, 95670
                        • Eisenhower Medical Center | Rancho Mirage, California, United States, 92270
                        • Kaiser Permanente- Marshall Medical Offices | Redwood City, California, United States, 94063
                        • Kaiser Permanente-Redwood City | Redwood City, California, United States, 94063
                        • Kaiser Permanente-Richmond | Richmond, California, United States, 94801
                        • Kaiser Permanente-Riverside | Riverside, California, United States, 92505
                        • Mercy Cancer Center - Rocklin | Rocklin, California, United States, 95765
                        • Rohnert Park Cancer Center | Rohnert Park, California, United States, 94928
                        • Kaiser Permanente-Roseville | Roseville, California, United States, 95661
                        • Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville, California, United States, 95661
                        • Sutter Roseville Medical Center | Roseville, California, United States, 95661
                        • The Permanente Medical Group-Roseville Radiation Oncology | Roseville, California, United States, 95678
                        • Kaiser Permanente Downtown Commons | Sacramento, California, United States, 95814
                        • Mercy Cancer Center - Sacramento | Sacramento, California, United States, 95816
                        • Sutter Medical Center Sacramento | Sacramento, California, United States, 95816
                        • Kaiser Permanente-South Sacramento | Sacramento, California, United States, 95823
                        • South Sacramento Cancer Center | Sacramento, California, United States, 95823
                        • Kaiser Permanente - Sacramento | Sacramento, California, United States, 95825
                        • Kaiser Permanente-San Diego Mission | San Diego, California, United States, 92108
                        • Kaiser Permanente-San Diego Zion | San Diego, California, United States, 92120
                        • California Pacific Medical Center-Pacific Campus | San Francisco, California, United States, 94115
                        • Kaiser Permanente-San Francisco | San Francisco, California, United States, 94115
                        • UCSF Medical Center-Mission Bay | San Francisco, California, United States, 94158
                        • Kaiser Permanente-Santa Teresa-San Jose | San Jose, California, United States, 95119
                        • Kaiser Permanente San Leandro | San Leandro, California, United States, 94577
                        • Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo, California, United States, 93401
                        • Kaiser Permanente-San Marcos | San Marcos, California, United States, 92078
                        • Kaiser Permanente-San Rafael | San Rafael, California, United States, 94903
                        • Kaiser San Rafael-Gallinas | San Rafael, California, United States, 94903
                        • Kaiser Permanente Medical Center - Santa Clara | Santa Clara, California, United States, 95051
                        • Palo Alto Medical Foundation-Santa Cruz | Santa Cruz, California, United States, 95065
                        • Mission Hope Medical Oncology - Santa Maria | Santa Maria, California, United States, 93444
                        • Kaiser Permanente-Santa Rosa | Santa Rosa, California, United States, 95403
                        • Sutter Pacific Medical Foundation | Santa Rosa, California, United States, 95403
                        • Kaiser Permanente Cancer Treatment Center | South San Francisco, California, United States, 94080
                        • Kaiser Permanente-South San Francisco | South San Francisco, California, United States, 94080
                        • Kaiser Permanente-Stockton | Stockton, California, United States, 95210
                        • Palo Alto Medical Foundation-Sunnyvale | Sunnyvale, California, United States, 94086
                        • Northbay Cancer Center | Vacaville, California, United States, 95687
                        • Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville, California, United States, 95687
                        • Kaiser Permanente Medical Center-Vacaville | Vacaville, California, United States, 95688
                        • Kaiser Permanente-Vallejo | Vallejo, California, United States, 94589
                        • Sutter Solano Medical Center/Cancer Center | Vallejo, California, United States, 94589
                        • Kaiser Permanente-Walnut Creek | Walnut Creek, California, United States, 94596
                        • Epic Care Cyberknife Center | Walnut Creek, California, United States, 94597
                        • John Muir Medical Center-Walnut Creek | Walnut Creek, California, United States, 94598
                        • Kaiser Permanente-Woodland Hills | Woodland Hills, California, United States, 91367
                        • Woodland Memorial Hospital | Woodland, California, United States, 95695
                        • Rocky Mountain Cancer Centers-Aurora | Aurora, Colorado, United States, 80012
                        • The Medical Center of Aurora | Aurora, Colorado, United States, 80012
                        • UCHealth University of Colorado Hospital | Aurora, Colorado, United States, 80045
                        • Boulder Community Hospital | Boulder, Colorado, United States, 80301
                        • Boulder Community Foothills Hospital | Boulder, Colorado, United States, 80303
                        • Rocky Mountain Cancer Centers-Boulder | Boulder, Colorado, United States, 80304
                        • Rocky Mountain Cancer Centers - Centennial | Centennial, Colorado, United States, 80112
                        • Penrose-Saint Francis Healthcare | Colorado Springs, Colorado, United States, 80907
                        • Rocky Mountain Cancer Centers-Penrose | Colorado Springs, Colorado, United States, 80907
                        • Saint Francis Cancer Center | Colorado Springs, Colorado, United States, 80923
                        • Cancer Center of Colorado at Sloan's Lake | Denver, Colorado, United States, 80204
                        • Denver Health Medical Center | Denver, Colorado, United States, 80204
                        • Kaiser Permanente-Franklin | Denver, Colorado, United States, 80205
                        • National Jewish Health-Main Campus | Denver, Colorado, United States, 80206
                        • The Women's Imaging Center | Denver, Colorado, United States, 80209
                        • Porter Adventist Hospital | Denver, Colorado, United States, 80210
                        • Colorado Blood Cancer Institute | Denver, Colorado, United States, 80218
                        • Presbyterian - Saint Lukes Medical Center - Health One | Denver, Colorado, United States, 80218
                        • Rocky Mountain Cancer Centers-Midtown | Denver, Colorado, United States, 80218
                        • SCL Health Saint Joseph Hospital | Denver, Colorado, United States, 80218
                        • Rocky Mountain Cancer Centers-Rose | Denver, Colorado, United States, 80220
                        • Rose Medical Center | Denver, Colorado, United States, 80220
                        • Western Surgical Care | Denver, Colorado, United States, 80220
                        • Mercy Medical Center | Durango, Colorado, United States, 81301
                        • Southwest Oncology PC | Durango, Colorado, United States, 81301
                        • Mountain Blue Cancer Care Center - Swedish | Englewood, Colorado, United States, 80113
                        • Rocky Mountain Cancer Centers - Swedish | Englewood, Colorado, United States, 80113
                        • Swedish Medical Center | Englewood, Colorado, United States, 80113
                        • The Melanoma and Skin Cancer Institute | Englewood, Colorado, United States, 80113
                        • Poudre Valley Hospital | Fort Collins, Colorado, United States, 80524
                        • Mountain Blue Cancer Care Center | Golden, Colorado, United States, 80401
                        • National Jewish Health-Western Hematology Oncology | Golden, Colorado, United States, 80401
                        • Saint Mary's Hospital and Regional Medical Center | Grand Junction, Colorado, United States, 81501
                        • North Colorado Medical Center | Greeley, Colorado, United States, 80631
                        • Good Samaritan Medical Center | Lafayette, Colorado, United States, 80026
                        • Kaiser Permanente-Rock Creek | Lafayette, Colorado, United States, 80026
                        • Rocky Mountain Cancer Centers-Lakewood | Lakewood, Colorado, United States, 80228
                        • Saint Anthony Hospital | Lakewood, Colorado, United States, 80228
                        • Rocky Mountain Cancer Centers-Littleton | Littleton, Colorado, United States, 80120
                        • Littleton Adventist Hospital | Littleton, Colorado, United States, 80122
                        • Kaiser Permanente-Lone Tree | Lone Tree, Colorado, United States, 80124
                        • Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree, Colorado, United States, 80124
                        • Sky Ridge Medical Center | Lone Tree, Colorado, United States, 80124
                        • Longmont United Hospital | Longmont, Colorado, United States, 80501
                        • Rocky Mountain Cancer Centers-Longmont | Longmont, Colorado, United States, 80501
                        • McKee Medical Center | Loveland, Colorado, United States, 80539
                        • Parker Adventist Hospital | Parker, Colorado, United States, 80138
                        • Rocky Mountain Cancer Centers-Parker | Parker, Colorado, United States, 80138
                        • Saint Mary Corwin Medical Center | Pueblo, Colorado, United States, 81004
                        • Rocky Mountain Cancer Centers - Pueblo | Pueblo, Colorado, United States, 81008
                        • National Jewish Health-Northern Hematology Oncology | Thornton, Colorado, United States, 80260
                        • Rocky Mountain Cancer Centers-Thornton | Thornton, Colorado, United States, 80260
                        • SCL Health Lutheran Medical Center | Wheat Ridge, Colorado, United States, 80033
                        • Danbury Hospital | Danbury, Connecticut, United States, 06810
                        • Hartford Hospital | Hartford, Connecticut, United States, 06102
                        • The Hospital of Central Connecticut | New Britain, Connecticut, United States, 06050
                        • Norwalk Hospital | Norwalk, Connecticut, United States, 06856
                        • Beebe South Coastal Health Campus | Frankford, Delaware, United States, 19945
                        • Beebe Medical Center | Lewes, Delaware, United States, 19958
                        • Delaware Clinical and Laboratory Physicians PA | Newark, Delaware, United States, 19713
                        • Helen F Graham Cancer Center | Newark, Delaware, United States, 19713
                        • Medical Oncology Hematology Consultants PA | Newark, Delaware, United States, 19713
                        • Christiana Care Health System-Christiana Hospital | Newark, Delaware, United States, 19718
                        • Beebe Health Campus | Rehoboth Beach, Delaware, United States, 19971
                        • TidalHealth Nanticoke / Allen Cancer Center | Seaford, Delaware, United States, 19973
                        • Christiana Care Health System-Wilmington Hospital | Wilmington, Delaware, United States, 19801
                        • Kaiser Permanente-Capitol Hill Medical Center | Washington, District of Columbia, United States, 20002
                        • Sibley Memorial Hospital | Washington, District of Columbia, United States, 20016
                        • Mount Sinai Comprehensive Cancer Center at Aventura | Aventura, Florida, United States, 33180
                        • Holy Cross Hospital | Fort Lauderdale, Florida, United States, 33308
                        • Mount Sinai Medical Center | Miami Beach, Florida, United States, 33140
                        • Sacred Heart Hospital | Pensacola, Florida, United States, 32504
                        • Sarasota Memorial Hospital | Sarasota, Florida, United States, 34239
                        • Emory University Hospital Midtown | Atlanta, Georgia, United States, 30308
                        • Emory University Hospital/Winship Cancer Institute | Atlanta, Georgia, United States, 30322
                        • Emory Saint Joseph's Hospital | Atlanta, Georgia, United States, 30342
                        • Northside Hospital | Atlanta, Georgia, United States, 30342
                        • Augusta University Medical Center | Augusta, Georgia, United States, 30912
                        • Northeast Georgia Medical Center Braselton | Braselton, Georgia, United States, 30517
                        • Northside Hospital-Forsyth | Cumming, Georgia, United States, 30041
                        • Dekalb Medical Center | Decatur, Georgia, United States, 30033
                        • Northeast Georgia Medical Center-Gainesville | Gainesville, Georgia, United States, 30501
                        • CTCA at Southeastern Regional Medical Center | Newnan, Georgia, United States, 30265
                        • Low Country Cancer Care | Savannah, Georgia, United States, 31404
                        • Memorial Health University Medical Center | Savannah, Georgia, United States, 31404
                        • Summit Cancer Care-Memorial | Savannah, Georgia, United States, 31404
                        • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah, Georgia, United States, 31405
                        • Summit Cancer Care-Candler | Savannah, Georgia, United States, 31405
                        • Hawaii Cancer Care - Westridge | 'Aiea, Hawaii, United States, 96701
                        • Pali Momi Medical Center | 'Aiea, Hawaii, United States, 96701
                        • Queen's Cancer Center - Pearlridge | 'Aiea, Hawaii, United States, 96701
                        • The Cancer Center of Hawaii-Pali Momi | 'Aiea, Hawaii, United States, 96701
                        • Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu, Hawaii, United States, 96813
                        • Island Urology | Honolulu, Hawaii, United States, 96813
                        • Queen's Cancer Cenrer - POB I | Honolulu, Hawaii, United States, 96813
                        • Queen's Medical Center | Honolulu, Hawaii, United States, 96813
                        • Straub Clinic and Hospital | Honolulu, Hawaii, United States, 96813
                        • University of Hawaii Cancer Center | Honolulu, Hawaii, United States, 96813
                        • Hawaii Cancer Care Inc-Liliha | Honolulu, Hawaii, United States, 96817
                        • Kuakini Medical Center | Honolulu, Hawaii, United States, 96817
                        • Queen's Cancer Center - Kuakini | Honolulu, Hawaii, United States, 96817
                        • The Cancer Center of Hawaii-Liliha | Honolulu, Hawaii, United States, 96817
                        • Kaiser Permanente Moanalua Medical Center | Honolulu, Hawaii, United States, 96819
                        • Kapiolani Medical Center for Women and Children | Honolulu, Hawaii, United States, 96826
                        • Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue, Hawaii, United States, 96766
                        • Saint Alphonsus Cancer Care Center-Boise | Boise, Idaho, United States, 83706
                        • Saint Luke's Cancer Institute - Boise | Boise, Idaho, United States, 83712
                        • Saint Alphonsus Cancer Care Center-Caldwell | Caldwell, Idaho, United States, 83605
                        • Kootenai Health - Coeur d'Alene | Coeur d'Alene, Idaho, United States, 83814
                        • Walter Knox Memorial Hospital | Emmett, Idaho, United States, 83617
                        • Saint Luke's Cancer Institute - Fruitland | Fruitland, Idaho, United States, 83619
                        • Idaho Urologic Institute-Meridian | Meridian, Idaho, United States, 83642
                        • Saint Luke's Cancer Institute - Meridian | Meridian, Idaho, United States, 83642
                        • Saint Luke's Cancer Institute - Nampa | Nampa, Idaho, United States, 83686
                        • Saint Alphonsus Cancer Care Center-Nampa | Nampa, Idaho, United States, 83687
                        • Kootenai Clinic Cancer Services - Post Falls | Post Falls, Idaho, United States, 83854
                        • Kootenai Cancer Clinic | Sandpoint, Idaho, United States, 83864
                        • Saint Luke's Cancer Institute - Twin Falls | Twin Falls, Idaho, United States, 83301
                        • Saint Anthony's Health | Alton, Illinois, United States, 62002
                        • Rush - Copley Medical Center | Aurora, Illinois, United States, 60504
                        • Illinois CancerCare-Bloomington | Bloomington, Illinois, United States, 61704
                        • Illinois CancerCare-Canton | Canton, Illinois, United States, 61520
                        • Memorial Hospital of Carbondale | Carbondale, Illinois, United States, 62902
                        • SIH Cancer Institute | Carterville, Illinois, United States, 62918
                        • Illinois CancerCare-Carthage | Carthage, Illinois, United States, 62321
                        • Centralia Oncology Clinic | Centralia, Illinois, United States, 62801
                        • Northwestern University | Chicago, Illinois, United States, 60611
                        • John H Stroger Jr Hospital of Cook County | Chicago, Illinois, United States, 60612
                        • Rush University Medical Center | Chicago, Illinois, United States, 60612
                        • University of Illinois | Chicago, Illinois, United States, 60612
                        • University of Chicago Comprehensive Cancer Center | Chicago, Illinois, United States, 60637
                        • Carle at The Riverfront | Danville, Illinois, United States, 61832
                        • Cancer Care Specialists of Illinois - Decatur | Decatur, Illinois, United States, 62526
                        • Decatur Memorial Hospital | Decatur, Illinois, United States, 62526
                        • Illinois CancerCare-Dixon | Dixon, Illinois, United States, 61021
                        • Carle Physician Group-Effingham | Effingham, Illinois, United States, 62401
                        • Crossroads Cancer Center | Effingham, Illinois, United States, 62401
                        • Illinois CancerCare-Eureka | Eureka, Illinois, United States, 61530
                        • NorthShore University HealthSystem-Evanston Hospital | Evanston, Illinois, United States, 60201
                        • Illinois CancerCare-Galesburg | Galesburg, Illinois, United States, 61401
                        • Western Illinois Cancer Treatment Center | Galesburg, Illinois, United States, 61401
                        • Northwestern Medicine Cancer Center Delnor | Geneva, Illinois, United States, 60134
                        • NorthShore University HealthSystem-Glenbrook Hospital | Glenview, Illinois, United States, 60026
                        • NorthShore University HealthSystem-Highland Park Hospital | Highland Park, Illinois, United States, 60035
                        • Sudarshan K Sharma MD Limited-Gynecologic Oncology | Hinsdale, Illinois, United States, 60521
                        • Illinois CancerCare-Kewanee Clinic | Kewanee, Illinois, United States, 61443
                        • Northwestern Medicine Lake Forest Hospital | Lake Forest, Illinois, United States, 60045
                        • Illinois CancerCare-Macomb | Macomb, Illinois, United States, 61455
                        • Carle Physician Group-Mattoon/Charleston | Mattoon, Illinois, United States, 61938
                        • Loyola University Medical Center | Maywood, Illinois, United States, 60153
                        • Marjorie Weinberg Cancer Center at Loyola-Gottlieb | Melrose Park, Illinois, United States, 60160
                        • Good Samaritan Regional Health Center | Mount Vernon, Illinois, United States, 62864
                        • UC Comprehensive Cancer Center at Silver Cross | New Lenox, Illinois, United States, 60451
                        • Cancer Care Center of O'Fallon | O'Fallon, Illinois, United States, 62269
                        • University of Chicago Medicine-Orland Park | Orland Park, Illinois, United States, 60462
                        • Illinois CancerCare-Ottawa Clinic | Ottawa, Illinois, United States, 61350
                        • Illinois CancerCare-Pekin | Pekin, Illinois, United States, 61554
                        • Illinois CancerCare-Peoria | Peoria, Illinois, United States, 61615
                        • Methodist Medical Center of Illinois | Peoria, Illinois, United States, 61636
                        • Illinois CancerCare-Peru | Peru, Illinois, United States, 61354
                        • Valley Radiation Oncology | Peru, Illinois, United States, 61354
                        • Illinois CancerCare-Princeton | Princeton, Illinois, United States, 61356
                        • North Shore Medical Center | Skokie, Illinois, United States, 60076
                        • Southern Illinois University School of Medicine | Springfield, Illinois, United States, 62702
                        • Springfield Clinic | Springfield, Illinois, United States, 62702
                        • Memorial Medical Center | Springfield, Illinois, United States, 62781
                        • Southwest Illinois Health Services LLP | Swansea, Illinois, United States, 62226
                        • Carle Cancer Center | Urbana, Illinois, United States, 61801
                        • The Carle Foundation Hospital | Urbana, Illinois, United States, 61801
                        • Northwestern Medicine Cancer Center Warrenville | Warrenville, Illinois, United States, 60555
                        • Illinois CancerCare - Washington | Washington, Illinois, United States, 61571
                        • Rush-Copley Healthcare Center | Yorkville, Illinois, United States, 60560
                        • Midwestern Regional Medical Center | Zion, Illinois, United States, 60099
                        • Parkview Hospital Randallia | Fort Wayne, Indiana, United States, 46805
                        • Parkview Regional Medical Center | Fort Wayne, Indiana, United States, 46845
                        • Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis, Indiana, United States, 46202
                        • Franciscan Health Indianapolis | Indianapolis, Indiana, United States, 46237
                        • Ascension Saint Vincent Indianapolis Hospital | Indianapolis, Indiana, United States, 46260
                        • Franciscan Saint Elizabeth Health - Lafayette East | Lafayette, Indiana, United States, 47905
                        • Woodland Cancer Care Center | Michigan City, Indiana, United States, 46360
                        • Franciscan Health Mooresville | Mooresville, Indiana, United States, 46158
                        • Reid Health | Richmond, Indiana, United States, 47374
                        • Memorial Hospital of South Bend | South Bend, Indiana, United States, 46601
                        • Union Hospital | Terre Haute, Indiana, United States, 47804
                        • Medical Oncology and Hematology Associates-West Des Moines | Clive, Iowa, United States, 50325
                        • Mercy Cancer Center-West Lakes | Clive, Iowa, United States, 50325
                        • Alegent Health Mercy Hospital | Council Bluffs, Iowa, United States, 51503
                        • Greater Regional Medical Center | Creston, Iowa, United States, 50801
                        • Mercy Medical Center - Des Moines | Des Moines, Iowa, United States, 50314
                        • Mission Cancer and Blood - Laurel | Des Moines, Iowa, United States, 50314
                        • University of Iowa/Holden Comprehensive Cancer Center | Iowa City, Iowa, United States, 52242
                        • Mercy Medical Center-West Lakes | West Des Moines, Iowa, United States, 50266
                        • Coffeyville Regional Medical Center | Coffeyville, Kansas, United States, 67337
                        • Central Care Cancer Center - Garden City | Garden City, Kansas, United States, 67846
                        • Central Care Cancer Center - Great Bend | Great Bend, Kansas, United States, 67530
                        • HaysMed University of Kansas Health System | Hays, Kansas, United States, 67601
                        • University of Kansas Cancer Center | Kansas City, Kansas, United States, 66160
                        • Lawrence Memorial Hospital | Lawrence, Kansas, United States, 66044
                        • Olathe Health Cancer Center | Olathe, Kansas, United States, 66061
                        • University of Kansas Cancer Center-Overland Park | Overland Park, Kansas, United States, 66210
                        • University of Kansas Hospital-Indian Creek Campus | Overland Park, Kansas, United States, 66211
                        • Ascension Via Christi - Pittsburg | Pittsburg, Kansas, United States, 66762
                        • Salina Regional Health Center | Salina, Kansas, United States, 67401
                        • Cotton O'Neil Cancer Center / Stormont Vail Health | Topeka, Kansas, United States, 66606
                        • University of Kansas Health System Saint Francis Campus | Topeka, Kansas, United States, 66606
                        • University of Kansas Hospital-Westwood Cancer Center | Westwood, Kansas, United States, 66205
                        • Associates In Womens Health | Wichita, Kansas, United States, 67208
                        • Flaget Memorial Hospital | Bardstown, Kentucky, United States, 40004
                        • Baptist Health Corbin | Corbin, Kentucky, United States, 40701
                        • Commonwealth Cancer Center-Corbin | Corbin, Kentucky, United States, 40701
                        • Saint Elizabeth Healthcare Edgewood | Edgewood, Kentucky, United States, 41017
                        • Baptist Health Lexington | Lexington, Kentucky, United States, 40503
                        • Saint Joseph Radiation Oncology Resource Center | Lexington, Kentucky, United States, 40504
                        • Saint Joseph Hospital East | Lexington, Kentucky, United States, 40509
                        • Saint Joseph London | London, Kentucky, United States, 40741
                        • Jewish Hospital | Louisville, Kentucky, United States, 40202
                        • Norton Hospital Pavilion and Medical Campus | Louisville, Kentucky, United States, 40202
                        • Baptist Health Louisville | Louisville, Kentucky, United States, 40207
                        • Norton Suburban Hospital and Medical Campus | Louisville, Kentucky, United States, 40207
                        • Saints Mary and Elizabeth Hospital | Louisville, Kentucky, United States, 40215
                        • Norton Brownsboro Hospital and Medical Campus | Louisville, Kentucky, United States, 40241
                        • UofL Health Medical Center Northeast | Louisville, Kentucky, United States, 40245
                        • Baptist Health Madisonville/Merle Mahr Cancer Center | Madisonville, Kentucky, United States, 42431
                        • Baptist Health Paducah | Paducah, Kentucky, United States, 42003
                        • Jewish Hospital Medical Center South | Shepherdsville, Kentucky, United States, 40165
                        • Baton Rouge General Medical Center | Baton Rouge, Louisiana, United States, 70806
                        • Hematology/Oncology Clinic PLLC | Baton Rouge, Louisiana, United States, 70809
                        • Mary Bird Perkins Cancer Center | Baton Rouge, Louisiana, United States, 70809
                        • Medical Center of Baton Rouge | Baton Rouge, Louisiana, United States, 70816
                        • Ochsner High Grove | Baton Rouge, Louisiana, United States, 70836
                        • Women's Cancer Care-Covington | Covington, Louisiana, United States, 70433
                        • Tulane University Health Sciences Center | New Orleans, Louisiana, United States, 70112
                        • Ochsner Baptist Medical Center | New Orleans, Louisiana, United States, 70115
                        • Ochsner Medical Center Jefferson | New Orleans, Louisiana, United States, 70121
                        • Eastern Maine Medical Center | Bangor, Maine, United States, 04401
                        • Lafayette Family Cancer Center-EMMC | Brewer, Maine, United States, 04412
                        • Maine Medical Center- Scarborough Campus | Scarborough, Maine, United States, 04074
                        • Greater Baltimore Medical Center | Baltimore, Maryland, United States, 21204
                        • Kaiser Permanente-Woodlawn Medical Center | Baltimore, Maryland, United States, 21244
                        • Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore, Maryland, United States, 21287
                        • University of Maryland Shore Medical Center at Easton | Easton, Maryland, United States, 21601
                        • Kaiser Permanente-Gaithersburg Medical Center | Gaithersburg, Maryland, United States, 20879
                        • Kaiser Permanente - Kensington Medical Center | Kensington, Maryland, United States, 20895
                        • Kaiser Permanente - Largo Medical Center | Largo, Maryland, United States, 20774
                        • Lahey Hospital and Medical Center | Burlington, Massachusetts, United States, 01805
                        • Lahey Medical Center-Peabody | Peabody, Massachusetts, United States, 01960
                        • Baystate Medical Center | Springfield, Massachusetts, United States, 01199
                        • Winchester Hospital | Winchester, Massachusetts, United States, 01890
                        • UMass Memorial Medical Center - Memorial Division | Worcester, Massachusetts, United States, 01605
                        • Saint Joseph Mercy Hospital | Ann Arbor, Michigan, United States, 48106
                        • University of Michigan Comprehensive Cancer Center | Ann Arbor, Michigan, United States, 48109
                        • Bronson Battle Creek | Battle Creek, Michigan, United States, 49017
                        • Saint Joseph Mercy Brighton | Brighton, Michigan, United States, 48114
                        • Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton, Michigan, United States, 48114
                        • Henry Ford Cancer Institute-Downriver | Brownstown, Michigan, United States, 48183
                        • Saint Joseph Mercy Canton | Canton, Michigan, United States, 48188
                        • Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton, Michigan, United States, 48188
                        • Caro Cancer Center | Caro, Michigan, United States, 48723
                        • Saint Joseph Mercy Chelsea | Chelsea, Michigan, United States, 48118
                        • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea, Michigan, United States, 48118
                        • Hematology Oncology Consultants-Clarkston | Clarkston, Michigan, United States, 48346
                        • Newland Medical Associates-Clarkston | Clarkston, Michigan, United States, 48346
                        • Henry Ford Macomb Hospital-Clinton Township | Clinton Township, Michigan, United States, 48038
                        • Henry Ford Medical Center-Fairlane | Dearborn, Michigan, United States, 48126
                        • Wayne State University/Karmanos Cancer Institute | Detroit, Michigan, United States, 48201
                        • Henry Ford Hospital | Detroit, Michigan, United States, 48202
                        • Ascension Saint John Hospital | Detroit, Michigan, United States, 48236
                        • Great Lakes Cancer Management Specialists-Doctors Park | East China Township, Michigan, United States, 48054
                        • Weisberg Cancer Treatment Center | Farmington Hills, Michigan, United States, 48334
                        • Genesee Cancer and Blood Disease Treatment Center | Flint, Michigan, United States, 48503
                        • Genesee Hematology Oncology PC | Flint, Michigan, United States, 48503
                        • Genesys Hurley Cancer Institute | Flint, Michigan, United States, 48503
                        • Hurley Medical Center | Flint, Michigan, United States, 48503
                        • Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids, Michigan, United States, 49503
                        • Spectrum Health at Butterworth Campus | Grand Rapids, Michigan, United States, 49503
                        • Trinity Health Grand Rapids Hospital | Grand Rapids, Michigan, United States, 49503
                        • Academic Hematology Oncology Specialists | Grosse Pointe Woods, Michigan, United States, 48236
                        • Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods, Michigan, United States, 48236
                        • Michigan Breast Specialists-Grosse Pointe Woods | Grosse Pointe Woods, Michigan, United States, 48236
                        • Allegiance Health | Jackson, Michigan, United States, 49201
                        • Bronson Methodist Hospital | Kalamazoo, Michigan, United States, 49007
                        • West Michigan Cancer Center | Kalamazoo, Michigan, United States, 49007
                        • Ascension Borgess Cancer Center | Kalamazoo, Michigan, United States, 49009
                        • Borgess Medical Center | Kalamazoo, Michigan, United States, 49048
                        • Sparrow Hospital | Lansing, Michigan, United States, 48912
                        • Hope Cancer Clinic | Livonia, Michigan, United States, 48154
                        • Trinity Health Saint Mary Mercy Livonia Hospital | Livonia, Michigan, United States, 48154
                        • Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb, Michigan, United States, 48044
                        • Michigan Breast Specialists-Macomb Township | Macomb, Michigan, United States, 48044
                        • Saint Mary's Oncology/Hematology Associates of Marlette | Marlette, Michigan, United States, 48453
                        • Trinity Health Muskegon Hospital | Muskegon, Michigan, United States, 49444
                        • Lakeland Hospital Niles | Niles, Michigan, United States, 49120
                        • Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores, Michigan, United States, 49444
                        • Henry Ford Medical Center-Columbus | Novi, Michigan, United States, 48377
                        • 21st Century Oncology-Pontiac | Pontiac, Michigan, United States, 48341
                        • Hope Cancer Center | Pontiac, Michigan, United States, 48341
                        • Newland Medical Associates-Pontiac | Pontiac, Michigan, United States, 48341
                        • Saint Joseph Mercy Oakland | Pontiac, Michigan, United States, 48341
                        • Huron Medical Center PC | Port Huron, Michigan, United States, 48060
                        • Lake Huron Medical Center | Port Huron, Michigan, United States, 48060
                        • Spectrum Health Reed City Hospital | Reed City, Michigan, United States, 49677
                        • Ascension Saint Mary's Hospital | Saginaw, Michigan, United States, 48601
                        • Oncology Hematology Associates of Saginaw Valley PC | Saginaw, Michigan, United States, 48604
                        • Lakeland Medical Center Saint Joseph | Saint Joseph, Michigan, United States, 49085
                        • Marie Yeager Cancer Center | Saint Joseph, Michigan, United States, 49085
                        • Henry Ford Macomb Health Center - Shelby Township | Shelby, Michigan, United States, 48315
                        • Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights, Michigan, United States, 48312
                        • Ascension Saint Joseph Hospital | Tawas City, Michigan, United States, 48764
                        • Munson Medical Center | Traverse City, Michigan, United States, 49684
                        • Advanced Breast Care Center PLLC | Warren, Michigan, United States, 48088
                        • Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren, Michigan, United States, 48093
                        • Macomb Hematology Oncology PC | Warren, Michigan, United States, 48093
                        • Michigan Breast Specialists-Warren | Warren, Michigan, United States, 48093
                        • Saint John Macomb-Oakland Hospital | Warren, Michigan, United States, 48093
                        • Henry Ford West Bloomfield Hospital | West Bloomfield, Michigan, United States, 48322
                        • Saint Mary's Oncology/Hematology Associates of West Branch | West Branch, Michigan, United States, 48661
                        • University of Michigan Health - West | Wyoming, Michigan, United States, 49519
                        • Huron Gastroenterology PC | Ypsilanti, Michigan, United States, 48106
                        • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti, Michigan, United States, 48197
                        • Sanford Joe Lueken Cancer Center | Bemidji, Minnesota, United States, 56601
                        • Fairview Ridges Hospital | Burnsville, Minnesota, United States, 55337
                        • Minnesota Oncology - Burnsville | Burnsville, Minnesota, United States, 55337
                        • Cambridge Medical Center | Cambridge, Minnesota, United States, 55008
                        • Mercy Hospital | Coon Rapids, Minnesota, United States, 55433
                        • Fairview Southdale Hospital | Edina, Minnesota, United States, 55435
                        • Unity Hospital | Fridley, Minnesota, United States, 55432
                        • Fairview Clinics and Surgery Center Maple Grove | Maple Grove, Minnesota, United States, 55369
                        • Minnesota Oncology Hematology PA-Maplewood | Maplewood, Minnesota, United States, 55109
                        • Saint John's Hospital - Healtheast | Maplewood, Minnesota, United States, 55109
                        • Abbott-Northwestern Hospital | Minneapolis, Minnesota, United States, 55407
                        • Hennepin County Medical Center | Minneapolis, Minnesota, United States, 55415
                        • Health Partners Inc | Minneapolis, Minnesota, United States, 55454
                        • Monticello Cancer Center | Monticello, Minnesota, United States, 55362
                        • New Ulm Medical Center | New Ulm, Minnesota, United States, 56073
                        • Fairview Northland Medical Center | Princeton, Minnesota, United States, 55371
                        • North Memorial Medical Health Center | Robbinsdale, Minnesota, United States, 55422
                        • Park Nicollet Clinic - Saint Louis Park | Saint Louis Park, Minnesota, United States, 55416
                        • Regions Hospital | Saint Paul, Minnesota, United States, 55101
                        • United Hospital | Saint Paul, Minnesota, United States, 55102
                        • Saint Francis Regional Medical Center | Shakopee, Minnesota, United States, 55379
                        • Lakeview Hospital | Stillwater, Minnesota, United States, 55082
                        • Sanford Thief River Falls Medical Center | Thief River Falls, Minnesota, United States, 56701
                        • Ridgeview Medical Center | Waconia, Minnesota, United States, 55387
                        • Rice Memorial Hospital | Willmar, Minnesota, United States, 56201
                        • Minnesota Oncology Hematology PA-Woodbury | Woodbury, Minnesota, United States, 55125
                        • Sanford Cancer Center Worthington | Worthington, Minnesota, United States, 56187
                        • Fairview Lakes Medical Center | Wyoming, Minnesota, United States, 55092
                        • University of Mississippi Medical Center | Jackson, Mississippi, United States, 39216
                        • Saint Louis Cancer and Breast Institute-Ballwin | Ballwin, Missouri, United States, 63011
                        • Central Care Cancer Center - Bolivar | Bolivar, Missouri, United States, 65613
                        • Parkland Health Center-Bonne Terre | Bonne Terre, Missouri, United States, 63628
                        • Cox Cancer Center Branson | Branson, Missouri, United States, 65616
                        • Saint Francis Medical Center | Cape Girardeau, Missouri, United States, 63703
                        • Southeast Cancer Center | Cape Girardeau, Missouri, United States, 63703
                        • Parkland Health Center - Farmington | Farmington, Missouri, United States, 63640
                        • Capital Region Southwest Campus | Jefferson City, Missouri, United States, 65109
                        • Freeman Health System | Joplin, Missouri, United States, 64804
                        • Mercy Hospital Joplin | Joplin, Missouri, United States, 64804
                        • Truman Medical Centers | Kansas City, Missouri, United States, 64108
                        • University of Kansas Cancer Center at North Kansas City Hospital | North Kansas City, Missouri, United States, 64116
                        • Delbert Day Cancer Institute at PCRMC | Rolla, Missouri, United States, 65401
                        • Mercy Clinic-Rolla-Cancer and Hematology | Rolla, Missouri, United States, 65401
                        • Heartland Regional Medical Center | Saint Joseph, Missouri, United States, 64506
                        • Saint Louis Cancer and Breast Institute-South City | Saint Louis, Missouri, United States, 63109
                        • Washington University School of Medicine | Saint Louis, Missouri, United States, 63110
                        • Mercy Hospital South | Saint Louis, Missouri, United States, 63128
                        • Missouri Baptist Medical Center | Saint Louis, Missouri, United States, 63131
                        • Mercy Hospital Saint Louis | Saint Louis, Missouri, United States, 63141
                        • Sainte Genevieve County Memorial Hospital | Sainte Genevieve, Missouri, United States, 63670
                        • Mercy Hospital Springfield | Springfield, Missouri, United States, 65804
                        • CoxHealth South Hospital | Springfield, Missouri, United States, 65807
                        • Missouri Baptist Sullivan Hospital | Sullivan, Missouri, United States, 63080
                        • Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills, Missouri, United States, 63127
                        • Mercy Hospital Washington | Washington, Missouri, United States, 63090
                        • Community Hospital of Anaconda | Anaconda, Montana, United States, 59711
                        • Billings Clinic Cancer Center | Billings, Montana, United States, 59101
                        • Saint Vincent Healthcare | Billings, Montana, United States, 59101
                        • Saint Vincent Frontier Cancer Center | Billings, Montana, United States, 59102
                        • Bozeman Deaconess Hospital | Bozeman, Montana, United States, 59715
                        • Saint James Community Hospital and Cancer Treatment Center | Butte, Montana, United States, 59701
                        • Benefis Healthcare- Sletten Cancer Institute | Great Falls, Montana, United States, 59405
                        • Great Falls Clinic | Great Falls, Montana, United States, 59405
                        • Saint Peter's Community Hospital | Helena, Montana, United States, 59601
                        • Kalispell Regional Medical Center | Kalispell, Montana, United States, 59901
                        • Saint Patrick Hospital - Community Hospital | Missoula, Montana, United States, 59802
                        • Community Medical Hospital | Missoula, Montana, United States, 59804
                        • CHI Health Saint Francis | Grand Island, Nebraska, United States, 68803
                        • Heartland Hematology and Oncology | Kearney, Nebraska, United States, 68845
                        • CHI Health Good Samaritan | Kearney, Nebraska, United States, 68847
                        • Saint Elizabeth Regional Medical Center | Lincoln, Nebraska, United States, 68510
                        • Nebraska Methodist Hospital | Omaha, Nebraska, United States, 68114
                        • Alegent Health Immanuel Medical Center | Omaha, Nebraska, United States, 68122
                        • Hematology and Oncology Consultants PC | Omaha, Nebraska, United States, 68122
                        • Alegent Health Bergan Mercy Medical Center | Omaha, Nebraska, United States, 68124
                        • Alegent Health Lakeside Hospital | Omaha, Nebraska, United States, 68130
                        • Creighton University Medical Center | Omaha, Nebraska, United States, 68131
                        • University of Nebraska Medical Center | Omaha, Nebraska, United States, 68198
                        • Midlands Community Hospital | Papillion, Nebraska, United States, 68046
                        • Carson Tahoe Regional Medical Center | Carson City, Nevada, United States, 89703
                        • Cancer and Blood Specialists-Henderson | Henderson, Nevada, United States, 89052
                        • Comprehensive Cancer Centers of Nevada - Henderson | Henderson, Nevada, United States, 89052
                        • Comprehensive Cancer Centers of Nevada-Horizon Ridge | Henderson, Nevada, United States, 89052
                        • Las Vegas Cancer Center-Henderson | Henderson, Nevada, United States, 89052
                        • OptumCare Cancer Care at Seven Hills | Henderson, Nevada, United States, 89052
                        • Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson, Nevada, United States, 89074
                        • GenesisCare USA - Henderson | Henderson, Nevada, United States, 89074
                        • Las Vegas Urology - Green Valley | Henderson, Nevada, United States, 89074
                        • Las Vegas Urology - Pebble | Henderson, Nevada, United States, 89074
                        • Urology Specialists of Nevada - Green Valley | Henderson, Nevada, United States, 89074
                        • Las Vegas Urology - Pecos | Las Vegas, Nevada, United States, 89074
                        • Desert West Surgery | Las Vegas, Nevada, United States, 89102
                        • OptumCare Cancer Care at Charleston | Las Vegas, Nevada, United States, 89102
                        • University Medical Center of Southern Nevada | Las Vegas, Nevada, United States, 89102
                        • Hope Cancer Care of Nevada | Las Vegas, Nevada, United States, 89103
                        • Cancer and Blood Specialists-Shadow | Las Vegas, Nevada, United States, 89106
                        • Radiation Oncology Centers of Nevada Central | Las Vegas, Nevada, United States, 89106
                        • Urology Specialists of Nevada - Central | Las Vegas, Nevada, United States, 89106
                        • Women's Cancer Center of Nevada | Las Vegas, Nevada, United States, 89106
                        • GenesisCare USA - Las Vegas | Las Vegas, Nevada, United States, 89109
                        • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas, Nevada, United States, 89109
                        • Sunrise Hospital and Medical Center | Las Vegas, Nevada, United States, 89109
                        • HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas, Nevada, United States, 89113
                        • Las Vegas Prostate Cancer Center | Las Vegas, Nevada, United States, 89113
                        • Las Vegas Urology - Sunset | Las Vegas, Nevada, United States, 89113
                        • Urology Specialists of Nevada - Southwest | Las Vegas, Nevada, United States, 89113
                        • Radiation Oncology Centers of Nevada Southeast | Las Vegas, Nevada, United States, 89119
                        • Cancer Therapy and Integrative Medicine | Las Vegas, Nevada, United States, 89121
                        • Ann M Wierman MD LTD | Las Vegas, Nevada, United States, 89128
                        • Cancer and Blood Specialists-Tenaya | Las Vegas, Nevada, United States, 89128
                        • Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas, Nevada, United States, 89128
                        • GenesisCare USA - Vegas Tenaya | Las Vegas, Nevada, United States, 89128
                        • HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas, Nevada, United States, 89128
                        • Las Vegas Urology - Cathedral Rock | Las Vegas, Nevada, United States, 89128
                        • Las Vegas Urology - Smoke Ranch | Las Vegas, Nevada, United States, 89128
                        • OptumCare Cancer Care at MountainView | Las Vegas, Nevada, United States, 89128
                        • Urology Specialists of Nevada - Northwest | Las Vegas, Nevada, United States, 89128
                        • Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas, Nevada, United States, 89135
                        • Comprehensive Cancer Centers of Nevada - Town Center | Las Vegas, Nevada, United States, 89144
                        • Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas, Nevada, United States, 89144
                        • Summerlin Hospital Medical Center | Las Vegas, Nevada, United States, 89144
                        • Las Vegas Cancer Center-Medical Center | Las Vegas, Nevada, United States, 89148-2405
                        • Comprehensive Cancer Centers of Nevada | Las Vegas, Nevada, United States, 89148
                        • GenesisCare USA - Fort Apache | Las Vegas, Nevada, United States, 89148
                        • OptumCare Cancer Care at Fort Apache | Las Vegas, Nevada, United States, 89148
                        • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas, Nevada, United States, 89149
                        • Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas, Nevada, United States, 89169
                        • University Cancer Center | Las Vegas, Nevada, United States, 89169
                        • Hope Cancer Care of Nevada-Pahrump | Pahrump, Nevada, United States, 89048
                        • Renown Regional Medical Center | Reno, Nevada, United States, 89502
                        • Saint Mary's Regional Medical Center | Reno, Nevada, United States, 89503
                        • Radiation Oncology Associates | Reno, Nevada, United States, 89509
                        • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon, New Hampshire, United States, 03756
                        • Dartmouth Cancer Center - Nashua | Nashua, New Hampshire, United States, 03063
                        • Memorial Sloan Kettering Basking Ridge | Basking Ridge, New Jersey, United States, 07920
                        • AtlantiCare Health Park-Cape May Court House | Cape May Court House, New Jersey, United States, 08210
                        • AtlantiCare Surgery Center | Egg Harbor Township, New Jersey, United States, 08234
                        • Hackensack University Medical Center | Hackensack, New Jersey, United States, 07601
                        • The Cancer Institute of New Jersey Hamilton | Hamilton, New Jersey, United States, 08690
                        • Monmouth Medical Center Southern Campus | Lakewood, New Jersey, United States, 08701
                        • Monmouth Medical Center | Long Branch, New Jersey, United States, 07740
                        • Memorial Sloan Kettering Monmouth | Middletown, New Jersey, United States, 07748
                        • Memorial Sloan Kettering Bergen | Montvale, New Jersey, United States, 07645
                        • Rutgers Cancer Institute of New Jersey | New Brunswick, New Jersey, United States, 08903
                        • The Valley Hospital-Luckow Pavilion | Paramus, New Jersey, United States, 07652
                        • Neurosurgeons of New Jersey-Ridgewood | Ridgewood, New Jersey, United States, 07450
                        • Valley Hospital | Ridgewood, New Jersey, United States, 07450
                        • Robert Wood Johnson University Hospital Somerset | Somerville, New Jersey, United States, 08876
                        • Valley Medical Group - Wayne Multispecialty Practice | Wayne, New Jersey, United States, 07470
                        • Valley Health System-Hematology/Oncology | Westwood, New Jersey, United States, 07675
                        • University of New Mexico Cancer Center | Albuquerque, New Mexico, United States, 87102
                        • Southwest Gynecologic Oncology Associates Inc | Albuquerque, New Mexico, United States, 87106
                        • Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho, New Mexico, United States, 87124
                        • Women's Cancer Care Associates LLC | Albany, New York, United States, 12208
                        • Montefiore Medical Center-Einstein Campus | Bronx, New York, United States, 10461
                        • Montefiore Medical Center-Weiler Hospital | Bronx, New York, United States, 10461
                        • Montefiore Medical Center - Moses Campus | Bronx, New York, United States, 10467
                        • Roswell Park Cancer Institute | Buffalo, New York, United States, 14263
                        • Memorial Sloan Kettering Commack | Commack, New York, United States, 11725
                        • Memorial Sloan Kettering Westchester | Harrison, New York, United States, 10604
                        • Northwell Health/Center for Advanced Medicine | Lake Success, New York, United States, 11042
                        • Mount Sinai Chelsea | New York, New York, United States, 10011
                        • Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York, New York, United States, 10016
                        • Lenox Hill Hospital | New York, New York, United States, 10021
                        • Mount Sinai Hospital | New York, New York, United States, 10029
                        • Manhattan Eye Ear and Throat Hospital | New York, New York, United States, 10065
                        • Memorial Sloan Kettering Cancer Center | New York, New York, United States, 10065
                        • University of Rochester | Rochester, New York, United States, 14642
                        • State University of New York Upstate Medical University | Syracuse, New York, United States, 13210
                        • SUNY Upstate Medical Center-Community Campus | Syracuse, New York, United States, 13215
                        • Memorial Sloan Kettering Nassau | Uniondale, New York, United States, 11553
                        • Dickstein Cancer Treatment Center | White Plains, New York, United States, 10601
                        • Randolph Hospital | Asheboro, North Carolina, United States, 27203
                        • Hope Women's Cancer Centers-Asheville | Asheville, North Carolina, United States, 28816
                        • Cone Health Cancer Center at Alamance Regional | Burlington, North Carolina, United States, 27215
                        • UNC Lineberger Comprehensive Cancer Center | Chapel Hill, North Carolina, United States, 27599
                        • Carolinas Medical Center/Levine Cancer Institute | Charlotte, North Carolina, United States, 28203
                        • Novant Health Presbyterian Medical Center | Charlotte, North Carolina, United States, 28204
                        • Southeastern Medical Oncology Center-Clinton | Clinton, North Carolina, United States, 28328
                        • Atrium Health Cabarrus/LCI-Concord | Concord, North Carolina, United States, 28025
                        • Duke University Medical Center | Durham, North Carolina, United States, 27710
                        • Southeastern Medical Oncology Center-Goldsboro | Goldsboro, North Carolina, United States, 27534
                        • Wayne Memorial Hospital | Goldsboro, North Carolina, United States, 27534
                        • Cone Health Cancer Center | Greensboro, North Carolina, United States, 27403
                        • Margaret R Pardee Memorial Hospital | Hendersonville, North Carolina, United States, 28791
                        • Novant Health Presbyterian Medical Center Huntersville | Huntersville, North Carolina, United States, 28078
                        • Onslow Memorial Hospital | Jacksonville, North Carolina, United States, 28546
                        • Southeastern Medical Oncology Center-Jacksonville | Jacksonville, North Carolina, United States, 28546
                        • Novant Health Cancer Institute - Kernersville | Kernersville, North Carolina, United States, 27284
                        • Cone Heath Cancer Center at Mebane | Mebane, North Carolina, United States, 27302
                        • Novant Health Cancer Institute - Mount Airy | Mount Airy, North Carolina, United States, 27030
                        • Duke Raleigh Hospital | Raleigh, North Carolina, United States, 27609
                        • Annie Penn Memorial Hospital | Reidsville, North Carolina, United States, 27320
                        • Novant Health Cancer Institute - Statesville | Statesville, North Carolina, United States, 28625
                        • Novant Health Cancer Institute - Thomasville | Thomasville, North Carolina, United States, 27360
                        • Novant Health Cancer Institute - Wilkesboro | Wilkesboro, North Carolina, United States, 28659
                        • Novant Health New Hanover Regional Medical Center | Wilmington, North Carolina, United States, 28401
                        • Novant Health Forsyth Medical Center | Winston-Salem, North Carolina, United States, 27103
                        • Novant Health Oncology Specialists | Winston-Salem, North Carolina, United States, 27103
                        • Sanford Bismarck Medical Center | Bismarck, North Dakota, United States, 58501
                        • Sanford South University Medical Center | Fargo, North Dakota, United States, 58103
                        • Sanford Broadway Medical Center | Fargo, North Dakota, United States, 58122
                        • Sanford Roger Maris Cancer Center | Fargo, North Dakota, United States, 58122
                        • Aultman Alliance Community Hospital | Alliance, Ohio, United States, 44601
                        • UHHS-Chagrin Highlands Medical Center | Beachwood, Ohio, United States, 44122
                        • Indu and Raj Soin Medical Center | Beavercreek, Ohio, United States, 45431
                        • Strecker Cancer Center-Belpre | Belpre, Ohio, United States, 45714
                        • Saint Elizabeth Boardman Hospital | Boardman, Ohio, United States, 44512
                        • Aultman Health Foundation | Canton, Ohio, United States, 44710
                        • Dayton Physicians LLC-Miami Valley South | Centerville, Ohio, United States, 45459
                        • Miami Valley Hospital South | Centerville, Ohio, United States, 45459
                        • Geauga Hospital | Chardon, Ohio, United States, 44024
                        • Adena Regional Medical Center | Chillicothe, Ohio, United States, 45601
                        • University of Cincinnati Cancer Center-UC Medical Center | Cincinnati, Ohio, United States, 45219
                        • Good Samaritan Hospital - Cincinnati | Cincinnati, Ohio, United States, 45220
                        • Oncology Hematology Care Inc-Kenwood | Cincinnati, Ohio, United States, 45236
                        • Bethesda North Hospital | Cincinnati, Ohio, United States, 45242
                        • TriHealth Cancer Institute-Westside | Cincinnati, Ohio, United States, 45247
                        • TriHealth Cancer Institute-Anderson | Cincinnati, Ohio, United States, 45255
                        • Case Western Reserve University | Cleveland, Ohio, United States, 44106
                        • MetroHealth Medical Center | Cleveland, Ohio, United States, 44109
                        • Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland, Ohio, United States, 44111
                        • Cleveland Clinic Foundation | Cleveland, Ohio, United States, 44195
                        • Ohio State University Comprehensive Cancer Center | Columbus, Ohio, United States, 43210
                        • Mount Carmel East Hospital | Columbus, Ohio, United States, 43213
                        • Columbus Oncology and Hematology Associates Inc | Columbus, Ohio, United States, 43214
                        • Riverside Methodist Hospital | Columbus, Ohio, United States, 43214
                        • Grant Medical Center | Columbus, Ohio, United States, 43215
                        • The Mark H Zangmeister Center | Columbus, Ohio, United States, 43219
                        • Mount Carmel Health Center West | Columbus, Ohio, United States, 43222
                        • Doctors Hospital | Columbus, Ohio, United States, 43228
                        • Grandview Hospital | Dayton, Ohio, United States, 45405
                        • Good Samaritan Hospital - Dayton | Dayton, Ohio, United States, 45406
                        • Miami Valley Hospital | Dayton, Ohio, United States, 45409
                        • Dayton Physician LLC-Miami Valley Hospital North | Dayton, Ohio, United States, 45415
                        • Miami Valley Hospital North | Dayton, Ohio, United States, 45415
                        • Delaware Health Center-Grady Cancer Center | Delaware, Ohio, United States, 43015
                        • Delaware Radiation Oncology | Delaware, Ohio, United States, 43015
                        • Grady Memorial Hospital | Delaware, Ohio, United States, 43015
                        • Dublin Methodist Hospital | Dublin, Ohio, United States, 43016
                        • Mercy Cancer Center-Elyria | Elyria, Ohio, United States, 44035
                        • Armes Family Cancer Center | Findlay, Ohio, United States, 45840
                        • Blanchard Valley Hospital | Findlay, Ohio, United States, 45840
                        • Orion Cancer Care | Findlay, Ohio, United States, 45840
                        • Atrium Medical Center-Middletown Regional Hospital | Franklin, Ohio, United States, 45005-1066
                        • Dayton Physicians LLC-Atrium | Franklin, Ohio, United States, 45005
                        • Dayton Physicians LLC-Wayne | Greenville, Ohio, United States, 45331
                        • Wayne Hospital | Greenville, Ohio, United States, 45331
                        • Mount Carmel Grove City Hospital | Grove City, Ohio, United States, 43123
                        • Greater Dayton Cancer Center | Kettering, Ohio, United States, 45409
                        • First Dayton Cancer Care | Kettering, Ohio, United States, 45420
                        • Kettering Medical Center | Kettering, Ohio, United States, 45429
                        • Fairfield Medical Center | Lancaster, Ohio, United States, 43130
                        • Saint Rita's Medical Center | Lima, Ohio, United States, 45801
                        • OhioHealth Mansfield Hospital | Mansfield, Ohio, United States, 44903
                        • Marietta Memorial Hospital | Marietta, Ohio, United States, 45750
                        • OhioHealth Marion General Hospital | Marion, Ohio, United States, 43302
                        • Hillcrest Hospital Cancer Center | Mayfield Heights, Ohio, United States, 44124
                        • UH Seidman Cancer Center at Lake Health Mentor Campus | Mentor, Ohio, United States, 44060
                        • UH Seidman Cancer Center at Southwest General Hospital | Middleburg Heights, Ohio, United States, 44130
                        • Knox Community Hospital | Mount Vernon, Ohio, United States, 43050
                        • Licking Memorial Hospital | Newark, Ohio, United States, 43055
                        • Newark Radiation Oncology | Newark, Ohio, United States, 43055
                        • Mercy Health Perrysburg Cancer Center | Perrysburg, Ohio, United States, 43551
                        • Southern Ohio Medical Center | Portsmouth, Ohio, United States, 45662
                        • UH Seidman Cancer Center at Firelands Regional Medical Center | Sandusky, Ohio, United States, 44870
                        • Springfield Regional Cancer Center | Springfield, Ohio, United States, 45504
                        • Springfield Regional Medical Center | Springfield, Ohio, United States, 45505
                        • ProMedica Flower Hospital | Sylvania, Ohio, United States, 43560
                        • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Toledo, Ohio, United States, 43606
                        • Saint Vincent Mercy Medical Center | Toledo, Ohio, United States, 43608
                        • Mercy Health - Saint Anne Hospital | Toledo, Ohio, United States, 43623
                        • Dayton Physicians LLC - Troy | Troy, Ohio, United States, 45373
                        • Upper Valley Medical Center | Troy, Ohio, United States, 45373
                        • University Hospitals Sharon Health Center | Wadsworth, Ohio, United States, 44281
                        • Saint Joseph Warren Hospital | Warren, Ohio, United States, 44484
                        • University of Cincinnati Cancer Center-West Chester | West Chester, Ohio, United States, 45069
                        • Saint Ann's Hospital | Westerville, Ohio, United States, 43081
                        • UH Seidman Cancer Center at Saint John Medical Center | Westlake, Ohio, United States, 44145
                        • UHHS-Westlake Medical Center | Westlake, Ohio, United States, 44145
                        • Saint Elizabeth Youngstown Hospital | Youngstown, Ohio, United States, 44501
                        • Genesis Healthcare System Cancer Care Center | Zanesville, Ohio, United States, 43701
                        • University of Oklahoma Health Sciences Center | Oklahoma City, Oklahoma, United States, 73104
                        • Mercy Hospital Oklahoma City | Oklahoma City, Oklahoma, United States, 73120
                        • Cancer Treatment Centers of America | Tulsa, Oklahoma, United States, 74133
                        • Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa, Oklahoma, United States, 74146
                        • Saint Alphonsus Medical Center-Baker City | Baker City, Oregon, United States, 97814
                        • Saint Charles Health System | Bend, Oregon, United States, 97701
                        • Clackamas Radiation Oncology Center | Clackamas, Oregon, United States, 97015
                        • Providence Cancer Institute Clackamas Clinic | Clackamas, Oregon, United States, 97015
                        • Bay Area Hospital | Coos Bay, Oregon, United States, 97420
                        • Legacy Mount Hood Medical Center | Gresham, Oregon, United States, 97030
                        • Providence Newberg Medical Center | Newberg, Oregon, United States, 97132
                        • Saint Alphonsus Medical Center-Ontario | Ontario, Oregon, United States, 97914
                        • Legacy Good Samaritan Hospital and Medical Center | Portland, Oregon, United States, 97210
                        • Providence Portland Medical Center | Portland, Oregon, United States, 97213
                        • Providence Saint Vincent Medical Center | Portland, Oregon, United States, 97225
                        • Legacy Meridian Park Hospital | Tualatin, Oregon, United States, 97062
                        • Jefferson Abington Hospital | Abington, Pennsylvania, United States, 19001
                        • Lehigh Valley Hospital-Cedar Crest | Allentown, Pennsylvania, United States, 18103
                        • Saint Luke's University Hospital-Bethlehem Campus | Bethlehem, Pennsylvania, United States, 18015
                        • Lehigh Valley Hospital - Muhlenberg | Bethlehem, Pennsylvania, United States, 18017
                        • Bryn Mawr Hospital | Bryn Mawr, Pennsylvania, United States, 19010
                        • Christiana Care Health System-Concord Health Center | Chadds Ford, Pennsylvania, United States, 19317
                        • Chambersburg Hospital | Chambersburg, Pennsylvania, United States, 17201
                        • Main Line Health Center-Collegeville | Collegeville, Pennsylvania, United States, 19426
                        • Geisinger Medical Center | Danville, Pennsylvania, United States, 17822
                        • Pocono Medical Center | East Stroudsburg, Pennsylvania, United States, 18301
                        • Ephrata Cancer Center | Ephrata, Pennsylvania, United States, 17522
                        • Main Line Health Center-Exton | Exton, Pennsylvania, United States, 19341
                        • Adams Cancer Center | Gettysburg, Pennsylvania, United States, 17325
                        • Cherry Tree Cancer Center | Hanover, Pennsylvania, United States, 17331
                        • UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Harrisburg, Pennsylvania, United States, 17109
                        • Geisinger Medical Center-Cancer Center Hazleton | Hazleton, Pennsylvania, United States, 18201
                        • Lehigh Valley Hospital-Hazleton | Hazleton, Pennsylvania, United States, 18201
                        • Jefferson Hospital | Jefferson Hills, Pennsylvania, United States, 15025
                        • Lancaster General Ann B Barshinger Cancer Institute | Lancaster, Pennsylvania, United States, 17601
                        • Lancaster General Hospital | Lancaster, Pennsylvania, United States, 17602
                        • Sechler Family Cancer Center | Lebanon, Pennsylvania, United States, 17042
                        • Geisinger Medical Oncology-Lewisburg | Lewisburg, Pennsylvania, United States, 17837
                        • Lewistown Hospital | Lewistown, Pennsylvania, United States, 17044
                        • Riddle Memorial Hospital | Media, Pennsylvania, United States, 19063
                        • Forbes Hospital | Monroeville, Pennsylvania, United States, 15146
                        • Medical Center Clinic-New Castle Office | New Castle, Pennsylvania, United States, 16105
                        • Paoli Memorial Hospital | Paoli, Pennsylvania, United States, 19301
                        • University of Pennsylvania/Abramson Cancer Center | Philadelphia, Pennsylvania, United States, 19104
                        • Thomas Jefferson University Hospital | Philadelphia, Pennsylvania, United States, 19107
                        • Allegheny General Hospital | Pittsburgh, Pennsylvania, United States, 15212
                        • West Penn Hospital | Pittsburgh, Pennsylvania, United States, 15224
                        • University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh, Pennsylvania, United States, 15232
                        • Geisinger Cancer Services-Pottsville | Pottsville, Pennsylvania, United States, 17901
                        • Community Medical Center | Scranton, Pennsylvania, United States, 18510
                        • Geisinger Medical Oncology-Selinsgrove | Selinsgrove, Pennsylvania, United States, 17870
                        • Geisinger Medical Group | State College, Pennsylvania, United States, 16801
                        • Chester County Hospital | West Chester, Pennsylvania, United States, 19380
                        • Reading Hospital | West Reading, Pennsylvania, United States, 19611
                        • Wexford Health and Wellness Pavilion | Wexford, Pennsylvania, United States, 15090
                        • Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre, Pennsylvania, United States, 18711
                        • Asplundh Cancer Pavilion | Willow Grove, Pennsylvania, United States, 19090
                        • Lankenau Medical Center | Wynnewood, Pennsylvania, United States, 19096
                        • WellSpan Health-York Cancer Center | York, Pennsylvania, United States, 17403
                        • WellSpan Health-York Hospital | York, Pennsylvania, United States, 17403
                        • Women and Infants Hospital | Providence, Rhode Island, United States, 02905
                        • AnMed Health Cancer Center | Anderson, South Carolina, United States, 29621
                        • Medical University of South Carolina | Charleston, South Carolina, United States, 29425
                        • Gibbs Cancer Center-Gaffney | Gaffney, South Carolina, United States, 29341
                        • Saint Francis Hospital | Greenville, South Carolina, United States, 29601
                        • Saint Francis Cancer Center | Greenville, South Carolina, United States, 29607
                        • Gibbs Cancer Center-Pelham | Greer, South Carolina, United States, 29651
                        • Spartanburg Medical Center | Spartanburg, South Carolina, United States, 29303
                        • MGC Hematology Oncology-Union | Union, South Carolina, United States, 29379
                        • Rapid City Regional Hospital | Rapid City, South Dakota, United States, 57701
                        • Sanford Cancer Center Oncology Clinic | Sioux Falls, South Dakota, United States, 57104
                        • Avera Cancer Institute | Sioux Falls, South Dakota, United States, 57105
                        • Sanford USD Medical Center - Sioux Falls | Sioux Falls, South Dakota, United States, 57117-5134
                        • Bristol Regional Medical Center | Bristol, Tennessee, United States, 37620
                        • Memorial Hospital | Chattanooga, Tennessee, United States, 37404
                        • Vanderbilt-Ingram Cancer Center Cool Springs | Franklin, Tennessee, United States, 37067
                        • Pulmonary Medicine Center of Chattanooga-Hixson | Hixson, Tennessee, United States, 37343
                        • Wellmont Medical Associates Oncology and Hematology-Johnson City | Johnson City, Tennessee, United States, 37604
                        • Ballad Health Cancer Care - Kingsport | Kingsport, Tennessee, United States, 37660
                        • Wellmont Holston Valley Hospital and Medical Center | Kingsport, Tennessee, United States, 37660
                        • Thompson Cancer Survival Center | Knoxville, Tennessee, United States, 37916
                        • Thompson Cancer Survival Center - West | Knoxville, Tennessee, United States, 37932
                        • Vanderbilt Breast Center at One Hundred Oaks | Nashville, Tennessee, United States, 37204
                        • Vanderbilt University/Ingram Cancer Center | Nashville, Tennessee, United States, 37232
                        • Thompson Oncology Group-Oak Ridge | Oak Ridge, Tennessee, United States, 37830
                        • Memorial GYN Plus | Ooltewah, Tennessee, United States, 37363
                        • Saint Joseph Regional Cancer Center | Bryan, Texas, United States, 77802
                        • Parkland Memorial Hospital | Dallas, Texas, United States, 75235
                        • UT Southwestern/Simmons Cancer Center-Dallas | Dallas, Texas, United States, 75390
                        • UT Southwestern/Simmons Cancer Center-Fort Worth | Fort Worth, Texas, United States, 76104
                        • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston, Texas, United States, 77030
                        • Ben Taub General Hospital | Houston, Texas, United States, 77030
                        • Houston Methodist Hospital | Houston, Texas, United States, 77030
                        • Methodist Willowbrook Hospital | Houston, Texas, United States, 77070
                        • Houston Methodist West Hospital | Houston, Texas, United States, 77094
                        • Houston Methodist Sugar Land Hospital | Sugar Land, Texas, United States, 77479
                        • Houston Methodist The Woodlands Hospital | The Woodlands, Texas, United States, 77385
                        • Wellmont Medical Associates-Bristol | Bristol, Virginia, United States, 24201
                        • Kaiser Permanente-Burke Medical Center | Burke, Virginia, United States, 22015
                        • University of Virginia Cancer Center | Charlottesville, Virginia, United States, 22908
                        • Inova Schar Cancer Institute | Fairfax, Virginia, United States, 22031
                        • Inova Fairfax Hospital | Falls Church, Virginia, United States, 22042
                        • Kaiser Permanente Tysons Corner Medical Center | McLean, Virginia, United States, 22102
                        • Southwest VA Regional Cancer Center | Norton, Virginia, United States, 24273
                        • Virginia Gynecologic Oncology | Richmond, Virginia, United States, 23229
                        • Virginia Commonwealth University/Massey Cancer Center | Richmond, Virginia, United States, 23298
                        • Carilion Clinic Gynecological Oncology | Roanoke, Virginia, United States, 24016
                        • Providence Regional Cancer System-Aberdeen | Aberdeen, Washington, United States, 98520
                        • MultiCare Auburn Medical Center | Auburn, Washington, United States, 98001
                        • Virginia Mason Bainbridge Island Medical Center | Bainbridge Island, Washington, United States, 98110
                        • Overlake Medical Center | Bellevue, Washington, United States, 98004
                        • PeaceHealth Saint Joseph Medical Center | Bellingham, Washington, United States, 98225
                        • Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton, Washington, United States, 98310
                        • Harrison Medical Center | Bremerton, Washington, United States, 98310
                        • Highline Medical Center-Main Campus | Burien, Washington, United States, 98166
                        • Providence Regional Cancer System-Centralia | Centralia, Washington, United States, 98531
                        • Swedish Cancer Institute-Edmonds | Edmonds, Washington, United States, 98026
                        • Saint Elizabeth Hospital | Enumclaw, Washington, United States, 98022
                        • Providence Regional Cancer Partnership | Everett, Washington, United States, 98201
                        • Virginia Mason Federal Way Medical Center | Federal Way, Washington, United States, 98002
                        • Saint Francis Hospital | Federal Way, Washington, United States, 98003
                        • Tacoma/Valley Radiation Oncology Centers-Gig Harbor | Gig Harbor, Washington, United States, 98332
                        • MultiCare Gig Harbor Medical Park | Gig Harbor, Washington, United States, 98335
                        • Swedish Cancer Institute-Issaquah | Issaquah, Washington, United States, 98029
                        • Kadlec Clinic Hematology and Oncology | Kennewick, Washington, United States, 99336
                        • Northwest Cancer Clinic | Kennewick, Washington, United States, 99336
                        • Providence Regional Cancer System-Lacey | Lacey, Washington, United States, 98503
                        • Saint Clare Hospital | Lakewood, Washington, United States, 98499
                        • PeaceHealth Saint John Medical Center | Longview, Washington, United States, 98632
                        • Virginia Mason Lynnwood Medical Center | Lynnwood, Washington, United States, 98036
                        • Jefferson Healthcare | Port Townsend, Washington, United States, 98368
                        • Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo, Washington, United States, 98370
                        • Peninsula Cancer Center | Poulsbo, Washington, United States, 98370
                        • MultiCare Good Samaritan Hospital | Puyallup, Washington, United States, 98372
                        • Tacoma/Valley Radiation Oncology Centers-Puyallup | Puyallup, Washington, United States, 98372
                        • Valley Medical Center | Renton, Washington, United States, 98055
                        • Virginia Mason Medical Center | Seattle, Washington, United States, 98101
                        • Pacific Gynecology Specialists | Seattle, Washington, United States, 98104
                        • Swedish Medical Center-Ballard Campus | Seattle, Washington, United States, 98107
                        • FHCC South Lake Union | Seattle, Washington, United States, 98109
                        • Fred Hutchinson Cancer Research Center | Seattle, Washington, United States, 98109
                        • Kaiser Permanente Washington | Seattle, Washington, United States, 98112
                        • Swedish Medical Center-Cherry Hill | Seattle, Washington, United States, 98122-5711
                        • Swedish Medical Center-First Hill | Seattle, Washington, United States, 98122
                        • University of Washington Medical Center - Montlake | Seattle, Washington, United States, 98195
                        • Providence Regional Cancer System-Shelton | Shelton, Washington, United States, 98584
                        • MultiCare Deaconess Cancer and Blood Specialty Center - Valley | Spokane Valley, Washington, United States, 99216
                        • MultiCare Deaconess Cancer and Blood Specialty Center - Downtown | Spokane, Washington, United States, 99204
                        • MultiCare Deaconess Cancer and Blood Specialty Center - North | Spokane, Washington, United States, 99218
                        • Tacoma/Valley Radiation Oncology Centers-Jackson Hall | Tacoma, Washington, United States, 97405
                        • Franciscan Research Center-Northwest Medical Plaza | Tacoma, Washington, United States, 98405
                        • MultiCare Tacoma General Hospital | Tacoma, Washington, United States, 98405
                        • Northwest Medical Specialties PLLC | Tacoma, Washington, United States, 98405
                        • Tacoma/Valley Radiation Oncology Centers-Saint Joe's | Tacoma, Washington, United States, 98405
                        • PeaceHealth Southwest Medical Center | Vancouver, Washington, United States, 98664
                        • Legacy Salmon Creek Hospital | Vancouver, Washington, United States, 98686
                        • Providence Saint Mary Regional Cancer Center | Walla Walla, Washington, United States, 99362
                        • North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima, Washington, United States, 98902
                        • Providence Regional Cancer System-Yelm | Yelm, Washington, United States, 98597
                        • United Hospital Center | Bridgeport, West Virginia, United States, 26330
                        • West Virginia University Charleston Division | Charleston, West Virginia, United States, 25304
                        • WVUH-Berkely Medical Center | Martinsburg, West Virginia, United States, 25401
                        • Monongalia Hospital | Morgantown, West Virginia, United States, 26505
                        • West Virginia University Healthcare | Morgantown, West Virginia, United States, 26506
                        • Camden Clark Medical Center | Parkersburg, West Virginia, United States, 26101
                        • Aurora Cancer Care-Southern Lakes VLCC | Burlington, Wisconsin, United States, 53105
                        • Marshfield Clinic-Chippewa Center | Chippewa Falls, Wisconsin, United States, 54729
                        • Marshfield Medical Center-EC Cancer Center | Eau Claire, Wisconsin, United States, 54701
                        • Aurora Health Center-Fond du Lac | Fond Du Lac, Wisconsin, United States, 54937
                        • Aurora Health Care Germantown Health Center | Germantown, Wisconsin, United States, 53022
                        • Aurora Cancer Care-Grafton | Grafton, Wisconsin, United States, 53024
                        • Saint Vincent Hospital Cancer Center Green Bay | Green Bay, Wisconsin, United States, 54301
                        • Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay, Wisconsin, United States, 54303
                        • Aurora BayCare Medical Center | Green Bay, Wisconsin, United States, 54311
                        • Mercyhealth Hospital and Cancer Center - Janesville | Janesville, Wisconsin, United States, 53548
                        • Aurora Cancer Care-Kenosha South | Kenosha, Wisconsin, United States, 53142
                        • Marshfield Clinic - Ladysmith Center | Ladysmith, Wisconsin, United States, 54848
                        • University of Wisconsin Carbone Cancer Center | Madison, Wisconsin, United States, 53792
                        • Aurora Bay Area Medical Group-Marinette | Marinette, Wisconsin, United States, 54143
                        • Marshfield Medical Center-Marshfield | Marshfield, Wisconsin, United States, 54449
                        • Aurora Cancer Care-Milwaukee | Milwaukee, Wisconsin, United States, 53209
                        • Aurora Saint Luke's Medical Center | Milwaukee, Wisconsin, United States, 53215
                        • Medical College of Wisconsin | Milwaukee, Wisconsin, United States, 53226
                        • Aurora Sinai Medical Center | Milwaukee, Wisconsin, United States, 53233
                        • Marshfield Clinic-Minocqua Center | Minocqua, Wisconsin, United States, 54548
                        • Cancer Center of Western Wisconsin | New Richmond, Wisconsin, United States, 54017
                        • Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls, Wisconsin, United States, 54154
                        • Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh, Wisconsin, United States, 54904
                        • Aurora Cancer Care-Racine | Racine, Wisconsin, United States, 53406
                        • Marshfield Medical Center-Rice Lake | Rice Lake, Wisconsin, United States, 54868
                        • Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan, Wisconsin, United States, 53081
                        • Marshfield Medical Center-River Region at Stevens Point | Stevens Point, Wisconsin, United States, 54482
                        • Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay, Wisconsin, United States, 54235-1495
                        • Aurora Medical Center in Summit | Summit, Wisconsin, United States, 53066
                        • Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers, Wisconsin, United States, 54241
                        • Marshfield Clinic-Wausau Center | Wausau, Wisconsin, United States, 54401
                        • Aurora Cancer Care-Milwaukee West | Wauwatosa, Wisconsin, United States, 53226
                        • Aurora West Allis Medical Center | West Allis, Wisconsin, United States, 53227
                        • Marshfield Medical Center - Weston | Weston, Wisconsin, United States, 54476
                        • Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids, Wisconsin, United States, 54494
                        • Cheyenne Regional Medical Center-West | Cheyenne, Wyoming, United States, 82001
                        • Billings Clinic-Cody | Cody, Wyoming, United States, 82414
                        • Welch Cancer Center | Sheridan, Wyoming, United States, 82801
                        • Advance Oncology Center | Aguadilla, Puerto Rico, 00603
                        • Doctor's Cancer Center-Arecibo | Arecibo, Puerto Rico, 00614
                        • Cancer Center-Metro Medical Center Bayamon | Bayamon, Puerto Rico, 00959-5060
                        • Hematologia Oncologia San Pablo | Bayamon, Puerto Rico, 00961
                        • HIMA San Pablo Oncologic Hospital | Caguas, Puerto Rico, 00726
                        • Doctors Cancer Center | Manati, Puerto Rico, 00674
                        • Instituto Oncologia Moderna Ponce | Ponce, Puerto Rico, 00716
                        • San Juan Community Oncology Group | San Juan, Puerto Rico, 00917
                        • Primary Care Physician Group | San Juan, Puerto Rico, 00920
                        • Centro Comprensivo de Cancer de UPR | San Juan, Puerto Rico, 00927
                        • San Juan City Hospital | San Juan, Puerto Rico, 00936
                        • Centro de Hematologia y Oncologia del Sur | Santa Isabel, Puerto Rico, 00757
                        Investigators
                        • Principal Investigator: Roisin E O'Cearbhaill, NRG Oncology

                        Study Documents (Full Text)

                        More Information

                        Additional Relevant MeSH Terms

                        • Carcinoma
                        • Adenocarcinoma
                        • Ovarian Neoplasms
                        • Carcinoma, Ovarian Epithelial
                        • Cystadenocarcinoma, Serous
                        • Fallopian Tube Neoplasms
                        • Carcinoma, Endometrioid
                        • Adenocarcinoma, Clear Cell
                        • Recurrence
                        • Neoplasms, Glandular and Epithelial
                        • Neoplasms by Histologic Type
                        • Neoplasms
                        • Disease Attributes
                        • Pathologic Processes
                        • Endocrine Gland Neoplasms
                        • Neoplasms by Site
                        • Ovarian Diseases
                        • Adnexal Diseases
                        • Genital Diseases, Female
                        • Female Urogenital Diseases
                        • Female Urogenital Diseases and Pregnancy Complications
                        • Urogenital Diseases
                        • Genital Neoplasms, Female
                        • Urogenital Neoplasms
                        • Genital Diseases
                        • Endocrine System Diseases
                        • Gonadal Disorders
                        • Cystadenocarcinoma
                        • Neoplasms, Cystic, Mucinous, and Serous
                        • Fallopian Tube Diseases
                        • Endometrial Neoplasms
                        • Uterine Neoplasms