Managing Adiposity-Related Diseases

Publication Date: February 28, 2024

Key Points

Key Points

  • Among the many conditions caused or worsened by excess adipose tissue (AT), the most prevalent are:
    • Cardiovascular disease (CVD)
    • Elevated blood sugar
    • High blood pressure
    • Dyslipidemia
    • Metabolic dysfunction-associated steatotic liver disease (MASLD)
    • Cancer
    • Obesity and stress: cause and effect
    • Psychiatric disease
  • These conditions are also largely improved, even prevented, by weight loss.
  • It is therefore recommended that weight loss be an integral part of management whenever excess AT accompanies any of these conditions.

Simplified Mechanism of Obesity, Insulin Resistance, and Metabolic Disease

a “Metabolic flexibility” is the ability of an organ to adapt to changes in energy demand and fuel management from fasting to fed states.

Disease Categories

...isease Categories...

...KEAWAY MESSAGES: Obesity and Diabe...


...Y MESSAGES: Obesity and High Blood Pre...


...ult Patients With Overweight or Obesity...


...Obesity (Adiposopathy) Cause Dia...


...0 TAKEAWAY MESSAGES: Obesity and CVD Obesity a...


...rect Adiposopathy (“Sick Fat”) Cardiova...


...irect Adiposopathy (“Sick Fat”) Cardiovascula...


...TAKEAWAY MESSAGES: Obesity and Women...


...10 TAKEAWAY MESSAGES: Obesity and Stress...


...AWAY MESSAGES: Obesity and Dyslipidemia T...


...c Dyslipidemia: (Hypertriglyceride...


...SSAGES: Obesity and MASLD MASLD has differe...


...10 TAKEAWAY MESSAGES: Obesity and Psychiatri...


...P 10 TAKEAWAY MESSAGES: Obesity and Cance...


...Associated Cancers Head and neck Meni...


Nutritional Factors that Increase Cancer Risk...


...er Risk Intentional weight loss...


...sical Activity in Patients With Can...