Management of Outpatient Parenteral Antimicrobial Therapy
Treatment
Patient Considerations
Antimicrobial and Catheter Utilization
Monitoring
- Data are insufficient to make evidence-based recommendations about specific tests and specific frequencies of monitoring for individual antimicrobials used in OPAT.
- The optimal frequency of measurement is undefined, but the general practice, in the setting of stable renal function, is once weekly.
- The frequency of office visits should be dictated by the treating physician, giving consideration to patient characteristics, the nature of the infection, the patient’s tolerance of and response to therapy, and individual patient social factors.
Antimicrobial Stewardship
Recommendation Grading
Overview
Title
Management of Outpatient Parenteral Antimicrobial Therapy
Authoring Organization
Infectious Diseases Society of America
Publication Month/Year
November 12, 2018
Last Updated Month/Year
March 4, 2024
Supplemental Implementation Tools
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Inclusion Criteria
Male, Female, Adolescent, Adult, Child, Infant, Older adult
Health Care Settings
Ambulatory, Outpatient
Intended Users
Nurse, nurse practitioner, physician, physician assistant
Scope
Treatment, Management
Keywords
parenteral antimicrobial therapy, OPAT, IV antimicrobial
Source Citation
Anne H Norris, Nabin K Shrestha, Genève M Allison, Sara C Keller, Kavita P Bhavan, John J Zurlo, Adam L Hersh, Lisa A Gorski, John A Bosso, Mobeen H Rathore, Antonio Arrieta, Russell M Petrak, Akshay Shah, Richard B Brown, Shandra L Knight, Craig A Umscheid, 2018 Infectious Diseases Society of America Clinical Practice Guideline for the Management of Outpatient Parenteral Antimicrobial Therapy, Clinical Infectious Diseases, Volume 68, Issue 1, 1 January 2019, Pages e1–e35, https://doi.org/10.1093/cid/ciy745