Vaccine Reactions

Publication Date: May 7, 2012

Key Points

Key Points

  • Immunization is perhaps the greatest public health achievement of all time, having significantly reduced the morbidity and mortality of many infectious diseases.
  • There are approximately 235 million doses of vaccines administered in the United States each year.
  • Anaphylactic reactions to vaccines are estimated to occur at a rate of approximately 1 per million doses.
  • Patients with suspected allergy to vaccines or vaccine components should be evaluated by an allergist/immunologist.
  • Most patients with suspected allergy to vaccines can receive vaccination safely.

Diagnosis and Assessment

...is and Assessment...

...local reactions and constitutional s...


...us events occurring after vaccine administration...


...asuring levels of IgG antibody to the immunizing...


...d anaphylactic reactions to vaccines...


...gE-mediated reactions to vaccines are more oft...


...ents who have had an apparent anap...


...rmal skin test result is negative, the chance tha...


...n patients with histories and skin tests...


...ous, and less common, reactions to...


...t women should not be vaccinated wit...


...l, live vaccines should not be given to persons...


...ccines or vaccination in general has b...


...Vaccines Bacille Calmette-Guerin (BCG)...


...accines Diphtheria, tetanus and acellular p...


...t of Vaccine Reactions...


...ote 1] Probable Anaphylactic...

...rring within 4 hours of vaccine administration...

...ssible Anaphylactic Reaction: Signs and/or...


...Vaccine Skin Test...

...rick test with full strength vaccine (co...

...rick test with full strength vaccine is negative...

...component/food skin prick tests: Influenza:...


...ote 3]...

...wer than the recommended number of doses...


...Note 4...

...dministration in graded doses: For a vac...