Vaccine Reactions

Publication Date: May 7, 2012

Key Points

Key Points

  • Immunization is perhaps the greatest public health achievement of all time, having significantly reduced the morbidity and mortality of many infectious diseases.
  • There are approximately 235 million doses of vaccines administered in the United States each year.
  • Anaphylactic reactions to vaccines are estimated to occur at a rate of approximately 1 per million doses.
  • Patients with suspected allergy to vaccines or vaccine components should be evaluated by an allergist/immunologist.
  • Most patients with suspected allergy to vaccines can receive vaccination safely.

Diagnosis and Assessment

...sis and Assessment

...al reactions and constitutional symptoms, such...


Live Vaccines Bacille Calmette-G...


...lled Vaccines Diphtheria, tetanus and acellu...


...ccine Reactions...


...Note 1] Probable Anaphylactic Reaction...


...cine Skin Tests Prick test with full strength...


...3] If fewer than the recommended nu...


...Vaccine administration in graded doses:...