Non-Fluoride Caries Preventive Agents

Publication Date: August 29, 2011
Last Updated: March 14, 2022

Recommendations

Polyol (Coronal Caries)

Advise parents and caregivers of children 5 years or older that use of sucrose-free polyol (xylitol only or polyol combinations) chewing gum for 10 to 20 minutes after meals may reduce incidence of coronal caries. (Weak)
335284
Advise adults that use of sucrose-free polyol (xylitol only or polyol combinations) chewing gum for 10 to 20 minutes after meals may reduce incidence of coronal caries. (Expert Opinion)
335284
Advise parents and caregivers of children 5 years or older that the daily use of xylitol-containing lozenges or hard candies that are dissolved slowly in the mouth after meals may reduce incidence of coronal caries (5-8 grams/day divided into two to three doses). (Expert Opinion)
335284

Chlorhexidine (Root Caries)

Apply 1:1 mixture of chlorhexidine-thymol varnish every three months to reduce the incidence of root caries. (In Favor)
335284
Applying 0.5 to 1.0 percent chlorhexidine gel alone or in combination with fluoride for prevention of root caries is not recommended. (Expert Opinion)
335284
Using 0.12 percent chlorhexidine rinse alone or in combination with fluoride for prevention of root caries is not recommended. (Against)
335284

Chlorhexidine (Coronal Caries)

Applying 1:1 mixture of chlorhexidine-thymol varnish alone or in combination with fluoride for prevention of coronal caries is not recommended. (Expert Opinion)
335284
Applying 10 to 40 percent chlorhexidine varnish alone or in combination with fluoride for prevention of coronal caries is not recommended. (Against)
335284
Applying 0.5 to 1.0 percent chlorhexidine gel alone or in combination with fluoride for prevention of coronal caries is not recommended. (Expert Opinion)
335284
Using 0.12 percent chlorhexidine rinse alone or in combination with fluoride for prevention of coronal caries is not recommended. (Against)
335284

Recommendation Grading

Overview

Title

Non-Fluoride Caries Preventive Agents

Authoring Organizations

Publication Month/Year

August 29, 2011

Last Updated Month/Year

July 26, 2023

Supplemental Implementation Tools

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

In this article, the authors present evidence-based clinical recommendations regarding the use of nonfluoride caries-preventive agents.

Target Patient Population

Children and adults at higher risk of developing caries

Inclusion Criteria

Female, Male, Adolescent, Adult, Child, Older adult

Health Care Settings

Ambulatory, Childcare center, School

Intended Users

Dentist, nurse, nurse practitioner, physician, physician assistant

Scope

Prevention, Management

Diseases/Conditions (MeSH)

D011315 - Preventive Medicine, D003731 - Dental Caries, D011313 - Preventive Dentistry, D014993 - Xylitol, D002710 - Chlorhexidine, D000149 - Acidulated Phosphate Fluoride

Keywords

preventive care, caries, dental caries, non-fluoride, caries-preventive agents