Coagulation Disorders in Patients With Cirrhosis
Publication Date: September 23, 2021
Key Points
Key Points
- Significant alterations in laboratory parameters — such as platelet count (PLT) and prothrombin time/international normalized ratio (PT/INR) — routinely accompany cirrhosis.
- However, the risks of both bleeding and thrombosis are not accurately quantitated by standard testing in this population.
- The best strategies to identify patients at risk for bleeding or thrombosis, to provide appropriate prophylaxis in patients at risk for clinically significant bleeding, to screen for and treat portal vein thrombosis, and to prevent clinically significant thromboembolic events are currently unknown.
Diagnosis
Diagnosi...
...ing Strategy...
...Testing (VET)In patients with stable c...
...INRIn patients with stable cirrhosis (with k...
...Vein Thrombosis (PVT) Screen...
...patients with cirrhosis, the AGA suggests a...
Treatment
Treatme...
...rocedure Prophylaxis...
...resh Frozen Plasma (FFP)In patients with stable...
...oietin receptor agonist (TPO-Ras)In...
Venous Thromboembolism (VTE) Prophylaxis W...
...zed patients with cirrhosis and who otherwise...
...Subacute Non-tumoral Portal Vein Thrombosis...
...ts with cirrhosis and acute or subacute n...
...l Fibrillation...
...tients with cirrhosis and atrial fibrilla...
...re Risk StratificationHaving trouble view...