Use of Opioids for Cancer Pain

Publication Date: December 4, 2022

Key Points

Key Points

  • Moderate-to-severe pain can be effectively manged with opioids, though serious challenges to their use exist, including well-characterized adverse events.
  • As a result of opioid misuse, opioid-related deaths and other challenges, people with cancer report stigma and concern related to opioid use.
  • Patients express fear of “addiction” along with guilt and a sense of moral failure that they require opioids, causing some to skip a dose or take a lower dose than prescribed.

Treatment

...reatmen...

...ion 1.1Opioids should be offered to patients wi...


...endation 1.2Prior to initiating opioid...


...ation 2.1For patients who are candidates...


...ndation 2.2Clinicians with limited exp...


...mendation 3.1Opioids should be initi...


...3.2Opioids should be initiated as immedia...


...ecommendation 3.3Patients who have be...


...ion 3.4Evidence remains insufficient to recommend...


...ommendation 3.5Evidence remains insufficie...


....6For patients with a substance use di...


...mendation 4Clinicians should proac...


...ecommendation 5.1For patients with r...


Recommendation 5.2For patients with renal or h...


...tions 6.1In patients receiving opioids ar...


...ndation 6.2Evidence remains insufficient t...


...ndation 7Opioid rotation should be offered to pa...


...tion and Management of Opioid-Induced Adver...