Management of Individuals with Diabetes at High Risk for Hypoglycemia

Publication Date: December 6, 2022

Key Points

Key Points

  • Hypoglycemia is associated with a number of unwanted outcomes including distress in those with diabetes and their caregivers, reductions in quality of life, and reductions in medication adherence, leading to increased risks for diabetes-related comorbidities.
  • Individuals with type 1 diabetes (T1D) may have clinically significant episodes of hypoglycemia as often as twice per week.
  • Those with type 2 diabetes (T2D) are at lower risk for hypoglycemia unless they have specific clinical characteristics that increase that risk, including the use of medications known to be associated with hypoglycemia (e.g., insulin, sulfonylureas), long duration of diabetes, and renal and/or hepatic dysfunction.

Definition of Terms

...efinition of Ter...

...continuous glucose monitoring (CGM)...


Evaluation

...luation

...s at High Risk for Developing Hypoglycemia Indi...


Treatment

...eatment...

...1Endocrine Society (ES) recommends CGM rather t...

...2ES suggests using real-time CGM and...

Recommendation 3ES suggests real-time C...

...n 4ES suggests initiation of CGM in the i...


...ecommended Candidates for the Init...


...ents Needed for Initiation of Continuous Glucos...


...ation 5ES suggests continuation of personal CGM...

Recommendation 6ES recommends that inpatient...

...7ES suggests long-acting insulin anal...


Table 5. Currently Available Insulin P...


...ation 8ES suggests that rapid-acting insulin ana...

...9ES recommends that a structured pr...


...ts of a Structured Diabetes Education Program in...


...dation 10ES recommends that glucagon p...


...ble 7. Currently Available Glucagon...