Pharmacologic Management of Premature Ejaculation

Publication Date: December 31, 2009
Last Updated: March 14, 2022

Guideline Statements

  • The diagnosis of PE is based on sexual history alone. A detailed sexual history should be obtained from all patients with ejaculatory complaints.
  • In patients with concomitant PE and ED, the ED should be treated first.
  • The risks and benefits of all treatment options should be discussed with the patient prior to any intervention. Patient and partner satisfaction is the primary target outcome for the treatment of PE.
  • Premature ejaculation can be treated effectively with several serotonin reuptake inhibitors (SRIs) or with topical anesthetics. The optimal treatment choice should be based on both physician judgment and patient preference.
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Recommendation Grading

Overview

Title

Pharmacologic Management of Premature Ejaculation

Authoring Organization

American Urological Association

Publication Month/Year

December 31, 2009

Last Updated Month/Year

January 4, 2024

Supplemental Implementation Tools

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

This clinical guideline discusses the evaluation and treatment of premature ejaculation. 

Inclusion Criteria

Male, Adult, Older adult

Health Care Settings

Ambulatory, Outpatient

Intended Users

Psychologist, nurse, nurse practitioner, physician, physician assistant

Scope

Assessment and screening, Management, Treatment

Diseases/Conditions (MeSH)

D061686 - Premature Ejaculation

Keywords

Premature Ejaculation, sexual dysfunction, ejaculatory dysfunction

Methodology

Number of Source Documents
284
Literature Search Start Date
December 9, 2019
Literature Search End Date
December 23, 2019