Chronic Idiopathic Constipation

Publication Date: May 18, 2023

Key Points

Key Points

  • Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
  • Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
  • A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.

Treatment

...atment...

Fibe...

...dation 1In adults with CIC, the panel suggests...


...smotic laxativ...

...mendation 2In adults with CIC, the pane...

...dation 3In adults with CIC, the panel suggests...

...ation 4In adults with CIC who fail or are intol...


...ant laxatives

...ommendation 5In adults with CIC, the pa...

...dation 6In adults with CIC, the pane...


...etagogues...

...mendation 7In adults with CIC who do not...

...on 8In adults with CIC who do not respond to O...

...tion 9In adults with CIC who do not respond...


...otonin type 4 (5-HT4) Agonis...

...0In adults with CIC who do not respon...


...The implementation considerations are based on t...


...view of Interventions for the Pharmac...