Chronic Idiopathic Constipation
Publication Date: May 18, 2023
Key Points
Key Points
- Chronic idiopathic constipation (CIC) is a common clinical diagnosis that affects approximately 8%–12% of the US population.
- Nonpharmacological therapies often represent the initial steps in management and may include dietary recommendations (such as increased fluid intake and increased dietary fiber) and behavioral changes (such as exercise). Pharmacological treatment may include the use of over-the-counter (OTC) or prescription medications, such as polyethylene glycol (PEG), secretagogues, or prokinetic agents.
- A significant proportion of patients with CIC are not satisfied with their treatment and may use multiple OTC medications, followed by prescription medications before they have improvement in their symptoms.
Treatment
Treatm...
...iber
...dation 1In adults with CIC, the panel sug...
Osmotic laxati...
...ation 2In adults with CIC, the panel recommends t...
...mmendation 3In adults with CIC, the pane...
...dation 4In adults with CIC who fail or a...
...imulant laxatives...
...5In adults with CIC, the panel reco...
...tion 6In adults with CIC, the panel...
Secretagog...
...In adults with CIC who do not respond to OT...
...8In adults with CIC who do not respond to OTC...
...In adults with CIC who do not respond to OTC...
...otonin type 4 (5-HT4) Agonist
...10In adults with CIC who do not respond to OTC ag...
...lementation considerations are based on the c...
...Overview of Interventions for the Pharmacol...