Treatment of Metastatic Carcinoma and Myeloma of the Femur
Overview
Overview
- The skeleton is a frequent site of metastasis in patients with cancer.
- Multiple myeloma is a plasma cell malignancy in which 70-80% of patients present with lytic lesions in the skeleton.
- Bone lesions, whether from metastatic carcinoma or multiple myeloma, can be painful and limit physical activity.
- They may require radiation therapy, surgery or both.
- Metastatic carcinoma or myeloma bone lesions that progress to pathologic fracture diminish functional capacity and quality of life and can potentially reduce overall survival.
Management
...nagement...
...g and Clinical Findin...
...the absence of reliable evidence, it is the o...
...cy of Bone Modifying Agents (BMAs)...
In the absence of reliable evidence,...
...age Response of BMAs...
...ld consider decreasing the frequen...
...MAs for Various Diagno...
...the absence of reliable evidence, it i...
...maging Findings and Atypical Fract...
...e absence of reliable evidence, it is...
...acy of Radiation Therapy...
...linicians should consider the use of radiation th...
...Therapy and Prophylactic Femur Stabilization...
...sence of reliable evidence, it is th...
...py after Resection and Reconstruction...
...sence of reliable evidence, it is the opinion of...
...ti-Fraction Radiation Treatment...
...should consider the use of multi-fract...
...ting Survival and Reconstruction...
...n the absence of reliable evidence, i...
...em Hemiarthroplasty...
...absence of reliable evidence, it is the opinio...
...alomedullary Nailing
...ence of reliable evidence, it is t...
...rthroplast...
...consider arthroplasty to improve patient function...