Treatment of Metastatic Carcinoma and Myeloma of the Femur
Overview
Overview
- The skeleton is a frequent site of metastasis in patients with cancer.
- Multiple myeloma is a plasma cell malignancy in which 70-80% of patients present with lytic lesions in the skeleton.
- Bone lesions, whether from metastatic carcinoma or multiple myeloma, can be painful and limit physical activity.
- They may require radiation therapy, surgery or both.
- Metastatic carcinoma or myeloma bone lesions that progress to pathologic fracture diminish functional capacity and quality of life and can potentially reduce overall survival.
Management
...anagemen...
...maging and Clinical Fin...
...the absence of reliable evidence, i...
...fficacy of Bone Modifying Agent...
...nce of reliable evidence, it is the opinio...
...ge Response of BMAs...
...hould consider decreasing the frequency...
...for Various Diagnoses...
...f reliable evidence, it is the opinion...
...ndings and Atypical Fractures
...absence of reliable evidence, it is the opi...
...icacy of Radiation T...
...uld consider the use of radiation therap...
...iation Therapy and Prophylactic Femur Stabilizatio...
...f reliable evidence, it is the opi...
...rapy after Resection and Reconstruction...
...f reliable evidence, it is the opinion...
...ti-Fraction Radiation Trea...
...hould consider the use of multi-fraction i...
...rvival and Reconstruction Method...
...absence of reliable evidence, it is the opin...
...tem Hemiarthroplasty...
...sence of reliable evidence, it is the opinio...
...alomedullary Nailing...
...nce of reliable evidence, it is the op...
...roplasty...
...may consider arthroplasty to improve patie...