Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice
Key Points
Key Points
- The rising prevalence of fungal infections is likely related to several factors, including an ever-growing population of susceptible patients.
- Furthermore, endemic mycoses continue to pose a threat to both immunocompetent and immunosuppressed individuals.
- Recent advances in laboratory diagnostics have evolved to assist the diagnosis of pulmonary fungal infections.
- These guidelines focus on the use of galactomannan (GM) antigen and PCR testing in the diagnosis of invasive pulmonary aspergillosis (IPA), (1➝3)-β-D-glucan (BDG) assays or invasive candidiasis (IC), and the use of antigen and antibody testing in the diagnosis of endemic mycoses.
Diagnosis
...iagnosis
...ble 2. Recommendatio...
...vasive fungal disease
...patients with severe immune compromise, suc...
...ts suspected of invasive fungal diseases,...
...pulmonary aspergillosis...
...patients with severe immune comprom...
...ients with severe immune compromise,...
In patients with severe immune compromise, su...
...ndidiasis
...ll patients in whom there is clinical concern for...
...oplasmosis...
...commends the use of Histoplasma antigen in...
...ests the use of Histoplasma serologie...
...astomycosis
...n patients with appropriate geographic ex...
...th suspected blastomycosis, the ATS suggests tha...
...ts with suspected blastomycosis, particularl...
Coccidioidomyco...
...ith appropriate geographic exposure and illness co...
...ents with suspected coccidioidomycosis, par...
...atients with suspected community acquired pneumon...