Vitamin D for Disease Prevention

Publication Date: June 3, 2024

Key Points

Key Points

  • Numerous studies demonstrate an association between serum concentrations of 25-hydroxyvitamin D (25[OH]D) and a variety of common disorders including musculoskeletal, metabolic, cardiovascular, malignant, autoimmune, and infectious diseases. This has led to widespread supplementation with vitamin D supplementation and increased laboratory testing for 25(OH)D in the general population.
  • The benefit-risk ratio of this increase in vitamin D supplementation is not clear, and the optimal vitamin D intake and serum 25(OH)D concentrations for disease prevention remain uncertain.
  • This guideline offers clinical guidelines for the use of vitamin D (cholecalciferol [vitamin D3] or ergocalciferol [vitamin D2]) to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH) D testing.

Treatment

Treatment

...hildren Ages 1–18...

...ecommendation 1...

...adolescents ages 1–18 years, we suggest empiric...


...pregnant Adults...

...mmendation 2...

...e general adult population younger than age 50...

...mendation 3...

...al adult population younger than age 50 yea...


...Aged 50–74 Years...

...commendation 4

In the general population ages 50 to 74 yea...

...mmendation 5

In the general population ages 50 to...


Adults Aged ≥75 Year...

...ommendation...

...the general population ages 75 years and o...

...mmendation...

...general population ages 75 years and o...


...egnancy

...mmendation 8...

...t empiric vitamin D supplementatio...

Recommendation...

...ancy, we suggest against routine 25(OH)...


...ediabetes (By Glycemic Criteria)...

...ommendation...

...r adults with high-risk prediabetes, in ad...


Dosing

...mmendation 1...

...ults ages 50 years and older who ha...


...thy Adults

...mendation 12...

In healthy adults, we suggest against routin...


...ith Dark Complexion...

...ecommendation...

...dark complexion, we suggest against routine scr...


...lts with Obesi...

Recommendation 1...

...obesity, we suggest against routine s...