![Endocrine Society Endocrine Society](https://54d4f314-8f94-415c-acb7-fd0a6332f070.s3.amazonaws.com/453/453__es-logo-lg__1361505270.png?X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAU2BE4PNFKE2WZV7V%2F20240908%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Date=20240908T000254Z&X-Amz-SignedHeaders=host&X-Amz-Expires=86400&X-Amz-Signature=92dcb15b82fec69b3be7ccf9b5436e2e0bf43a465ebed0d1a09b9993de81cdbd)
Vitamin D for Disease Prevention
Key Points
Key Points
- Numerous studies demonstrate an association between serum concentrations of 25-hydroxyvitamin D (25[OH]D) and a variety of common disorders including musculoskeletal, metabolic, cardiovascular, malignant, autoimmune, and infectious diseases. This has led to widespread supplementation with vitamin D supplementation and increased laboratory testing for 25(OH)D in the general population.
- The benefit-risk ratio of this increase in vitamin D supplementation is not clear, and the optimal vitamin D intake and serum 25(OH)D concentrations for disease prevention remain uncertain.
- This guideline offers clinical guidelines for the use of vitamin D (cholecalciferol [vitamin D3] or ergocalciferol [vitamin D2]) to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH) D testing.
Treatment
...atment...
...n Ages 1–18 Years...
...commendation...
...children and adolescents ages 1–1...
...regnant Adults...
...mmendation 2
...the general adult population younger than ag...
...mmendation 3...
...n the general adult population younger than ag...
...s Aged 50–74 Years...
Recommendation...
...eneral population ages 50 to 74 years, we su...
...mendation 5...
...neral population ages 50 to 74 years, we sug...
...dults Aged ≥75 Years...
...mmendation 6
...he general population ages 75 years and old...
...mendation 7...
...e general population ages 75 years...
...regnan...
Recommendation...
...ggest empiric vitamin D supplementatio...
...mmendation 9
..., we suggest against routine 25(OH)D testin...
Adults With Prediabetes (By Gly...
Recommendation 1...
...dults with high-risk prediabetes, in addition to...
Dosin...
...mmendation 11...
...50 years and older who have indications...
Healthy Adu...
...ommendation 12
...healthy adults, we suggest against...
...ults with Dark Complexion...
...commendation 13
...lts with dark complexion, we suggest against routi...
...ts with Obesit...
Recommendatio...
...adults with obesity, we suggest against routi...