Title

Antineoplastic Therapy Administration Safety Standards for Adult and Pediatric Oncology

Authoring Organizations

American Society of Clinical Oncology

Oncology Nursing Society

Publication Month/Year

May 22, 2024

Last Updated Month/Year

September 30, 2024

Supplemental Implementation Tools

Document Type

Other

Country of Publication

US

Document Objectives

To update the ASCO-Oncology Nursing Society (ONS) standards for antineoplastic therapy administration safety in adult and pediatric oncology and highlight current standards for antineoplastic therapy for adult and pediatric populations with various routes of administration and location.

Target Patient Population

Adult and pediatric patients with cancer receiving antineoplastic therapy.

Target Provider Population

Nonprofessional caregivers of patients with cancer.

PICO Questions

  1. What are standards for ordering, preparing, dispensing, and administering antineoplastic therapy?

  2. Does the care provided by oncology professionals who meet certain qualifications result in fewer medical errors and reduce preventable harm, compared with those who do not?

  3. Does the care provided by health care organization that have specific quality improvement or standardization of care policies in place result in fewer medical errors and reduce preventable harm compared with no or less specific policies?

  4. Do documentation policies mandated and/or implemented by health care organizations result in fewer medical errors and reduce preventable harm compared with no documentation policies?

  5. Do policies on treatment planning, patient consent, and patients' education result in fewer medical errors and reduce preventable harm, compared with those who do not?

  6. Do policies on ordering, preparing, dispensing, and administering antineoplastic therapy result in fewer medical errors and reduce preventable harm, compared with no or less specific policies?

  7. Do policies on ordering, preparing, dispensing, and administering antineoplastic therapy for patients at home result in fewer medical errors, reduce preventable harm, and increase adherence, compared with no or less specific policies?

  8. Do policies on ordering, preparing, dispensing, and administering antineoplastic therapy intrathecally or intraventricularly for patients result in fewer medical errors and reduce preventable harm, compared with those who do not?

  9. Do policies on post-treatment monitoring of adverse events from antineoplastic therapy result in fewer medical errors and reduce preventable harm, compared with no or less specific policies?

Inclusion Criteria

Male, Female, Adolescent, Adult, Child, Infant, Older adult

Health Care Settings

Ambulatory, Home health, Hospital, Outpatient

Intended Users

Nurse, nurse practitioner, community pharmacist, health systems pharmacist, pharmacy technician, physician, physician assistant

Scope

Treatment, Management, Prevention

Diseases/Conditions (MeSH)

D002173 - Cancer Care Facilities, D000903 - Antibiotics, Antineoplastic, D000964 - Antimetabolites, Antineoplastic, D000970 - Antineoplastic Agents, D018906 - Antineoplastic Agents, Alkylating, D000074322 - Antineoplastic Agents, Immunological, D000972 - Antineoplastic Agents, Phytogenic, D000971 - Antineoplastic Combined Chemotherapy Protocols, D024221 - Antineoplastic Protocols

Keywords

antineoplastic agents, standards, antineoplastic therapy

Source Citation

Siegel RD, LeFebvre KB, Temin S, et al. Antineoplastic Therapy Administration Safety Standards for Adult and Pediatric Oncology: ASCO-ONS Standards. JCO Oncol Pract. 2024 May 22. doi: 10.1200/OP.24.00216.

Supplemental Methodology Resources

Evidence Tables

Methodology

Number of Source Documents
90
Literature Search Start Date
January 1, 2015
Literature Search End Date
April 1, 2023