Endoscopic Eradication of Barrett’s Esophagus

Publication Date: May 17, 2024

Key Points

Key Points

  • In patients with Barrett’s esophagus (BE), counsel tobacco cessation and weight loss if overweight.
  • Refer patients with dysplastic BE to high-volume endoscopists with expertise in endoscopic eradication therapy (EET), pathologists with expertise in BE neoplasia, with access to multidisciplinary care.
  • Histologic diagnosis of BE dysplasia or early cancer should be confirmed by an expert pathologist.
  • In patients undergoing management of dysplastic BE, optimize reflux control with medication, lifestyle modifications, and assessing adherence.
  • Before embarking on EET, discuss risks and benefits of EET, need for adherence with reflux management, expected outcomes, need for continued surveillance after completion of EET, with adequate time to assess patient values and preferences.
  • The goal of EET should be complete eradication of intestinal metaplasia and neoplasia.
  • Failure to achieve complete eradication of intestinal metaplasia should prompt reassessment and optimization of reflux control.
  • Endoscopists and practices performing EET are encouraged to monitor key outcomes and quality metrics, including complete eradication of intestinal metaplasia and neoplasia and adverse events.

Treatment

...reatmen...

...igure 1. Endoscopic Eradication Therapy of Ba...


...dation 1In individuals with BE with high-grade dys...


...n 2In individuals with BE with low-grad...


...dation 3In individuals with NDBE, AGA...


...tion 4In patients undergoing EET, AGA...


...mmendation 5In individuals with BE with...