Treatment of Congenital Hemophilia A and B

Publication Date: June 19, 2024

Key Points

Key Points

  • Hemophilia is a congenital X-linked bleeding disorder that affects an estimated 1,125,000 individuals worldwide, 80% of whom have hemophilia A.
  • Individuals with severe (and some moderate) forms of hemophilia not treated with prophylaxis may experience spontaneous bleeding, of which the most frequent are joint and muscle bleeding.
  • Prophylaxis rather than episodic treatment is strongly recommended for severe and moderately-severe hemophilia A and B.

Treatment

...eatment

...a A Without Inhibitors...

...with severe and moderately-severe hemophili...

...dividuals with severe and moderately-severe hemop...

...with severe and moderately-severe he...

...limited settings in which the use...

...treated individuals with severe hemop...

...iduals with severe and moderately-se...


...hilia A With Inhibitors...

...ls with severe hemophilia A with inhibito...

...with severe hemophilia A with inh...

...ndividuals with severe hemophilia A with high-resp...

...individuals with severe hemophilia A wi...

...dividuals with severe hemophilia A with inhibito...


Hemophilia B Without I...

...ls with severe and moderately-severe...

In individuals with severe and moderately-sev...