Interstitial Lung Disease in People With Systemic Autoimmune Rheumatic Disease

Publication Date: July 8, 2024

Key Points

Key Points

Guideline Summary:

  • This guideline provides evidence-based recommendations for the screening and treatment of Interstitial Lung Disease (ILD) in people with Systemic Autoimmune Rheumatic Diseases (SARDs) (Rheumatoid Arthritis [RA], Systemic Sclerosis [SSc], Idiopathic Inflammatory Myositis [IIM including polymyositis, dermatomyositis, antisynthetase syndrome, immune-mediated necrotizing myopathy], Mixed Connective Tissue Disease [MCTD], and Sjögren’s Disease [SjD]) associated with the greatest risk of ILD, and for monitoring for ILD progression.

Screening and Monitoring

...eening and Monitoring...

...able 2. Risk Factors for the Develop...


...le 3. Summary of Recommendations for Screening of...

...mendations...

...SARDsa at increased risk of developing ILD, we co...

...h SARDs at increased risk of developing ILD, we co...

...ople with SARDs at increased risk of deve...

...ple with SARDs at increased risk of develo...

For people with SARDs at increased risk of...

...or people with SARDs at increased risk...

...people with SARDs at increased risk of devel...

...h SARDs at increased risk of developing...


...e 4. Summary of Recommendations for Monitoring...

...commendatio...

...ople with SARDs-ILD, we conditionally recommend...

...e with SARDs-ILD, we conditionally r...

...h SARDs-ILD, we conditionally recommend...

...ople with SARDs-ILD, we conditionally recommend m...

...SARDs-ILD, we conditionally recommend agains...

...people with SARDs-ILD, we conditiona...

...e with SARDs-ILD, we conditionally rec...

...eople with IIM-ILD and SSc-ILD, we sugge...

...r people with RA-ILD, SjD-ILD, and MC...

...SARDs-ILD, we do not provide guidance about...

...le with SARDs-ILD, we suggest assessment for amb...


...1. Recommendations for ILD Screening and Monito...


...Interstitial Lung Disease Screening...


Treatment

...reatme...

...ummary of Recommendations for Manage...

...ecommendat...

...ple with SARD-ILD other than SSc-ILD, we co...

...or people with SSc-ILD, we strongly recomm...

...th SARD-ILD, we conditionally recommend mycophe...

...th SSc-ILD and MCTD-ILD, we conditionally recommen...

...ith SARD-ILD, we conditionally recommen...

...h SSc-ILD, we conditionally recommen...

...or people with SjD-ILD, IIM-ILD, and MCTD-...

For people with RA-ILD, the Panel was not ab...

...h SARD-ILD, we conditionally recommend against p...

...h SARD-ILD receiving mycophenolate without e...

...with SARD-ILD, we conditionally recommend aga...

...IIM-ILD, we conditionally recommend JAK in...

...with SARD-ILD other than IIM-ILD, we condition...

...h IIM-ILD, we conditionally recommend calcineurin...

For people with SARD-ILD other than...

...r people with SARD-ILD, we conditi...

...ple with SARD-associated ILD, we conditionally...


...ble 6. Recommendations for Management of S...

...commendati...

...commend against using long-term glu...

...n other SARD-ILD we conditionally recommend a...

...th SARD-ILD progression despite first ILD...

...ple with RA-ILD progression despite first I...

...with SARD-ILD, other than RA-ILD, progression...

...people with SSc-ILD, MCTD-ILD, RA-ILD...

...with SjD-ILD and IIM-ILD progression despite firs...

...with IIM-ILD progression despite first IL...

...ith SARD-ILD, other than IIM-ILD, progre...

...e with IIM-ILD progression despite first ILD...

...h IIM-ILD and MCTD-ILD progression despite first...

...r people with SARD-ILD progression...

For people with SSc-ILD progression...


...ital Treatment Options for the Tre...


...mmendations for Management of SARD-ILD P...


...endations for Management of SARD With Rapidly Prog...

...mmendations

...eople with SARD and RP-ILD, we cond...

...ith SARD and RP-ILD, we conditionally...

...people with SARD and RP-ILD, we conditionally...

...th RP-ILD, we conditionally recommend up-fr...

...h SARD and RP-ILD, we conditionally recomm...

...r people with SARD and RP-ILD, we conditionally r...


...commendations for Management of SARD...