Title

Health Supervision for Children and Adolescents With Sickle Cell Disease

Authoring Organization

American Academy of Pediatrics

Publication Month/Year

July 22, 2024

Last Updated Month/Year

July 23, 2024

Supplemental Implementation Tools

Document Type

Consensus

Country of Publication

US

Document Objectives

Sickle cell disease (SCD) is a group of complex genetic disorders of hemoglobin with multisystem manifestations. The scope of this clinical report is such that in-depth recommendations for management of all complications is not possible. Rather, the authors present an overview focused on the practical management of children and adolescents with SCD and the complications that are of particular relevance to pediatric primary care providers. References with detailed commentary provide further information. Timely and appropriate treatment of acute illness is critical, because life-threatening complications may develop rapidly. Specialized comprehensive medical care decreases morbidity and mortality during childhood. The provision of comprehensive care is a time-intensive endeavor that includes ongoing patient and family education, periodic comprehensive evaluations and other disease-specific health maintenance services, nursing support, psychosocial care, and genetic counseling. Ideally, this care includes comanagement by the pediatrician or other pediatric primary care provider and a team of specialist SCD experts: Hematologist, other pediatric specialists, advanced practice providers, nurse specialists, social workers, patient navigators, and educational liaisons.

Target Patient Population

Children and adolescents with sickle cell disease

Target Provider Population

Pediatricians, hematologists, and allied providers caring for children and adolescents with sickle cell disease

Inclusion Criteria

Male, Female, Adolescent, Child, Infant

Health Care Settings

Ambulatory, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant

Scope

Management

Diseases/Conditions (MeSH)

D000755 - Anemia, Sickle Cell

Keywords

sickle cell disease, Sickle Cell, acute chest syndrome, erythrocyte transfusion, sickle cell anemia

Source Citation

Amber M. Yates, Banu Aygun, Rachelle Nuss, Zora R. Rogers, Section on Hematology/Oncology, AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY; Health Supervision for Children and Adolescents With Sickle Cell Disease: Clinical Report. Pediatrics 2024; e2024066842. 10.1542/peds.2024-066842

Supplemental Methodology Resources

Data Supplement