Title

Treatment of Systemic Sclerosis

Authoring Organization

European League Against Rheumatism (EULAR)

Publication Month/Year

October 11, 2024

Last Updated Month/Year

October 15, 2024

Supplemental Implementation Tools

Document Type

Guideline

Country of Publication

European

Document Objectives

To update the European Alliance of Associations for Rheumatology (EULAR) recommendations for treatment of systemic sclerosis (SSc), incorporating new evidence and therapies. These updated recommendations include the first set of synthetic and biological targeted therapies recommended for key fibrotic manifestations of SSc as well as first-line combination treatment for newly diagnosed pulmonary artery hypertension and prioritise a new research agenda for the coming years.

Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings

Ambulatory

Intended Users

Nurse, nurse practitioner, physician, physician assistant

Scope

Treatment, Management

Diseases/Conditions (MeSH)

D012598 - Sclerosis

Keywords

systemic sclerosis, systemic sclerosis (SSc)

Source Citation

Del Galdo F, Lescoat A, Conaghan PG, Bertoldo E, Čolić J, Santiago T, Suliman YA, Matucci-Cerinic M, Gabrielli A, Distler O, Hoffmann-Vold AM, Castellví I, Balbir-Gurman A, Vonk M, Ananyeva L, Rednic S, Tarasova A, Ostojic P, Boyadzhieva V, El Aoufy K, Farrington S, Galetti I, Denton CP, Kowal-Bielecka O, Mueller-Ladner U, Allanore Y. EULAR recommendations for the treatment of systemic sclerosis: 2023 update. Ann Rheum Dis. 2024 Oct 11:ard-2024-226430. doi: 10.1136/ard-2024-226430. Epub ahead of print. PMID: 39393843.

Methodology

Number of Source Documents
74
Literature Search Start Date
January 1, 2015
Literature Search End Date
March 31, 2023