Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck
Key Points
Key Points
Preoperative Evaluation
...rative Evaluation...
...tients undergoing evaluation for a...
...e-Needle aspiration or core biopsy of...
...human papillomavirus (HR-HPV) testing should be...
...t enhanced computed tomography (CECT) of...
...: If a primary is not evident on clinical e...
Diagnostic And Therapeutic Surgical Procedures
...ostic And Therapeutic Surgical Procedu...
2.1: Patients should undergo a complete ope...
...2: For patients with unilateral lymphadenopa...
...ts with bilateral lymphadenopathy, if a pri...
...4: For patients in whom the primary tumor i...
2.5: Tissue specimens from suspected prima...
...6: Intraoperative frozen section of biopsies...
Surgical Considerations
...rgical Consideration...
...all-volume bilateral neck disease with no c...
....3: Large-volume bilateral neck dise...
3.4: When primary surgery is planned, Levels II...
...r unilateral, small-volume neck disease, ei...
Radiotherapy
...otherapy
...ts receiving radiotherapy or concur...
...ients treated with primary radiotherapy for u...
...eated with primary radiotherapy for un...
4.4: In patients presenting with clini...
...ients with a clinicopathologic present...
...: Patients treated with primary radiotherapy fo...
...n addition to anatomic mucosal regi...
...tients treated with primary radiotherapy for N...
...9: For patients treated with primary radiotherapy,...
...receiving radiotherapy or concurrent chemor...
...ients for whom no primary site is patholo...
...Adjuvant radiotherapy should not be adm...
...3: Adjuvant radiotherapy should be administered t...
...t radiation dose to the dissected...
Systemic Therapy
...temic Therapy...
...urrent administration of cisplatin with defin...
...: Concurrent administration of cisplatin with...
...ent administration of cisplatin to adjuvant r...
...t administration of cisplatin with defini...
Figure 1. Diagnosis & Management Algorithm of SCCUP in the Head and Neck
.... Diagnosis & Management Algorithm of SC...
Figure 2. Diagnosis & Management Algorithm of SCCUP in the Head and Neck (continued)
...nosis & Management Algorithm of SCCUP...