Obesity

Publication Date: January 2, 2015

Key Points

Key Points

  • The Task Force agrees with the opinion of prominent medical societies that current scientific evidence supports the view that obesity is a disease.
  • Weight loss produces many benefits including risk factor improvement, prevention of disease, and improvements in feeling and function. Greater weight loss produces greater benefits, but modest (5%–10%) weight loss, such as that produced by lifestyle modifications and medications, has been shown to produce significant improvements in many conditions.
  • Medications used for the management of conditions other than obesity can contribute to or exacerbate weight gain in susceptible individuals. Many of these conditions are also associated with obesity.
  • Health care providers can help patients prevent or attenuate weight gain by appropriately prescribing medications that would promote weight loss or minimize weight gain when treating these conditions.
  • Health care providers can help selected patients successfully lose weight and maintain lost weight by appropriately prescribing weight loss medications or in some cases surgical intervention as an adjunct to lifestyle change.

Diagnosis

...agnosis

...Causes of ObesityHaving trouble viewing table? Ex...


...omorbid Conditions in Obesity and Evidence for...


Treatment

...eatment...

...ciety (ES) recommends that diet, exe...


...der to promote long-term weight maintenance, ES su...


...h uncontrolled HTN or history of heart disease,...


...s assessment of efficacy and safety at leas...


...atient’s response to a weight loss medicati...


...medication for chronic obesity management is...


...s with T2DM who are overweight or obes...


...ts with CVD who seek pharmacological...


...Weight Gain and Some Alternatives...

...commends weight-losing and weight-neutral...

...s with T2DM requiring insulin thera...

...ends ACE inhibitors, angiotensin rece...

...n antidepressant therapy is indicated, ES rec...

...ommends using weight-neutral antipsyc...

...ds considering weight gain potential in ch...

...BMI >27 kg/m2 with comorbidities or >30 kg/m...

...sts monitoring the weight and waist circu...

...sts the use of NSAIDs and disease-m...

...ggests the use of antihistamines with...


...f-Label Use of Drugs Approved for Other Indicat...

...ests against the off-label use of medications ap...


...gs Associated with Weight Gain and Sugges...


...le 4. Advantages and Disadvantages...


Table 5. Pharmacotherapy for Obesit...