Title
Lack of Evidence for MTHFR Polymorphism Testing
Authoring Organization
Publication Month/Year
February 1, 2013
Last Updated Month/Year
April 1, 2024
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Inclusion Criteria
Female, Male, Adult, Older adult
Health Care Settings
Ambulatory, Outpatient
Intended Users
Medical techologist technician, genetics, nurse, nurse practitioner, physician, physician assistant
Scope
Assessment and screening, Diagnosis, Management, Treatment
Diseases/Conditions (MeSH)
D011110 - Polymorphism, Genetic
Keywords
MTHFR, Polymorphism testing, folic acid, homocysteine, thermolabile variant, polymorphism
Source Citation
Bashford MT, Hickey SE, Curry CJ, Toriello HV; American College of Medical Genetics and Genomics (ACMG) Professional Practice and Guidelines Committee. Addendum: ACMG Practice Guideline: lack of evidence for MTHFR polymorphism testing. Genet Med. 2020 Dec;22(12):2125. doi: 10.1038/s41436-020-0843-0. Epub 2020 Jun 12. Erratum for: Genet Med. 2013 Feb;15(2):153-6. Erratum in: Genet Med. 2020 Jun 26;: PMID: 32533132.