Early Parkinson Disease
Key Points
Key Points
- The treatment options for the alleviation of motor symptoms in the early stages of Parkinson disease (PD) are based on the enhancement of dopaminergic tone with levodopa, monoamine oxidase inhibitors, dopamine agonists (DAs), or a combination thereof.
- The choice of initial treatment is influenced by the potential for neuropsychiatric adverse effects associated with DAs and dyskinesia and motor fluctuations associated with levodopa.
- The treatment options for the alleviation of motor symptoms in the early stages of Parkinson disease (PD) are based on the enhancement of dopaminergic tone with levodopa, monoamine oxidase inhibitors, dopamine agonists (DAs), or a combination thereof.
- The choice of initial treatment is influenced by the potential for neuropsychiatric adverse effects associated with DAs and dyskinesia and motor fluctuations associated with levodopa.
Treatment
Treatm...
...pa vs. DAs vs. MAO-B inhibitor...
...nicians should counsel patients with ear...
...nts with early PD who seek treatme...
...y prescribe DAs as the initial dopaminergic ther...
...ould not prescribe DAs to patients with ea...
...ibing levodopa...
...ould initially prescribe immediate-relea...
...tients with early PD, clinicians should prescrib...
...should routinely monitor patients taking levod...
...ld counsel patients taking levodopa that higher do...
...ians should counsel patients that...
...cribing DA...
...linicians should inform the patient and...
...cians should screen patients for cognitive impair...
...cians should screen patients for the presence o...
...s should involve caregivers in asses...
...linicians may screen patients for the p...
...uld integrate patient preferences concerning...
...hould prescribe the lowest dose of DA require...
...ering and Discontinuing D...
...ns should recommend tapering or dis...
...st be discontinued due to adverse...
...bing MAO-B inhibitors...
...cians should counsel patients with e...
...inicians may prescribe MAO-B inhibitors as the ini...
...or Parkinson DiseaseHaving trouble viewin...