Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma

Publication Date: November 14, 2021
Last Updated: March 14, 2022

Recommendation

In patients with asthma in whom treatment is being considered, we suggest the use of FeNO in addition to usual care over usual care alone.

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Recommendation Grading

Overview

Title

Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma

Authoring Organization

American Thoracic Society

Publication Month/Year

November 14, 2021

Last Updated Month/Year

August 30, 2024

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Target Provider Population

Clinicians who manage adults and children 4 years of age and older with asthma, including adult and pediatric pulmonologists, adult and pediatric allergists, internists, pediatricians, family medicine specialists, and other healthcare providers

Inclusion Criteria

Male, Female, Adolescent, Adult, Child, Older adult

Health Care Settings

Ambulatory

Intended Users

Nurse, nurse practitioner, physician, physician assistant, respiratory therapist

Scope

Assessment and screening, Management

Diseases/Conditions (MeSH)

D001249 - Asthma, D009569 - Nitric Oxide

Keywords

nasal nitric oxide, asthma, nitric oxide, FENO, FENO testing

Source Citation

Khatri SB, Iaccarino JM, Barochia A, Soghier I, Akuthota P, Brady A, Covar RA, Debley JS, Diamant Z, Fitzpatrick AM, Kaminsky DA, Kenyon NJ, Khurana S, Lipworth BJ, McCarthy K, Peters M, Que LG, Ross KR, Schneider-Futschik EK, Sorkness CA, Hallstrand TS; American Thoracic Society Assembly on Allergy, Immunology, and Inflammation. Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2021 Nov 15;204(10):e97-e109. doi: 10.1164/rccm.202109-2093ST. PMID: 34779751.

Supplemental Methodology Resources

Methodology Supplement