Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma
Recommendation
In patients with asthma in whom treatment is being considered, we suggest the use of FeNO in addition to usual care over usual care alone.
(C, L)Recommendation Grading
Overview
Title
Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma
Authoring Organization
American Thoracic Society
Publication Month/Year
November 14, 2021
Last Updated Month/Year
October 4, 2024
Supplemental Implementation Tools
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Document Objectives
To provide evidence-based clinical guidance on whether FENO testing is indicated to optimize asthma treatment in patients with asthma in whom treatment is being considered.
Target Patient Population
Patients with asthma
Target Provider Population
Clinicians who manage adults and children 4 years of age and older with asthma, including adult and pediatric pulmonologists, adult and pediatric allergists, internists, pediatricians, family medicine specialists, and other healthcare providers
Inclusion Criteria
Male, Female, Adolescent, Adult, Child, Older adult
Health Care Settings
Ambulatory
Intended Users
Nurse, nurse practitioner, physician, physician assistant, respiratory therapist
Scope
Assessment and screening, Management
Diseases/Conditions (MeSH)
D001249 - Asthma, D009569 - Nitric Oxide
Keywords
nasal nitric oxide, asthma, nitric oxide, FENO, FENO testing
Source Citation
Khatri SB, Iaccarino JM, Barochia A, Soghier I, Akuthota P, Brady A, Covar RA, Debley JS, Diamant Z, Fitzpatrick AM, Kaminsky DA, Kenyon NJ, Khurana S, Lipworth BJ, McCarthy K, Peters M, Que LG, Ross KR, Schneider-Futschik EK, Sorkness CA, Hallstrand TS; American Thoracic Society Assembly on Allergy, Immunology, and Inflammation. Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2021 Nov 15;204(10):e97-e109. doi: 10.1164/rccm.202109-2093ST. PMID: 34779751.