Atopic Dermatitis

Publication Date: December 17, 2023

Key Points

Key Points

  • Atopic dermatitis (AD) is the most common chronic inflammatory skin disease, spanning nations, age groups, ethnicities, and cultures.
  • Studies in the past 20 years reveal that it affects approximately 13% of children and 7% of adults worldwide.
  • AD usually develops in infancy, with 45% of patients developing symptoms by 6 months of age, 60% by 12 months, approximately 85% by 5 years and between 16% and 37% as adults.
  • Approximately 70% may have remission before adolescence, whereas 25% will continue to have AD into adulthood.
  • Rare syndromes (e.g., Wiskott-Aldrich syndrome) may present with AD.
  • Guidance addressing AD management, last issued in 2012 by the American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force, requires updating as a result of new treatments and improved guideline and evidence synthesis methodology.

Diagnosis

...gnosis...

...c Dermatitis Diagnostic Criteria as Def...


...re 1. Concepts of Induction of Remission and...


...2. Some Reported Severity Strata fo...


...d the full guideline and appendix for...


...mmendation 1Clinicians managing all...


Treatment

Treatmen...

...y of Comparative Effects of Topical Treatments o...


...3. List of Some Available Topical Corticos...


...e 4. Example of Some Available Topical Treatment S...


...League Table for Maintenance of Remiss...


...ation 2In patients with atopic dermatitis, th...


...n 3In patients with uncontrolled atopic dermatiti...


...commendation 4In patients aged 3 mo...


...tion 5In patients with localized uncontr...


...ommendation 6In patients with uncontr...


...In patients with mild-moderate atopic der...


...on 8In adolescent and adult patient...


...4. Summary of Comparative Effects of Systemic...


...Common Risk Factors for Cancer, Venous Thromb...


...dation 9In patients with uncontrolled atopic...


...0In patients with atopic dermatitis and...


...11In patients with moderate-severe atopi...


...ecommendation 12In patients with mild atopic de...


...mendation 13In patients with atopic...


...14In patients with moderate-severe atopic derma...


...endation 15In patients with mild a...


...mendation 16In patients 6 months of...


...endation 17In patients 12 years of a...


...tion 18In adults and adolescents with moder...


...commendation 19In adults and adolescents with m...


...endation 20In patients with moderat...


...ecommendation 21In patients with moderate-severe...


...commendation 22In patients with moderate-severe AD...


...ommendation 23In patients with moder...


...mmendation 24In patients with moder...


...commendation 25In patients with atopic de...