Title

Liberation from Mechanical Ventilation in Critically Ill Adults

Authoring Organizations

American College of Chest Physicians

American Thoracic Society

Publication Month/Year

January 4, 2017

Last Updated Month/Year

November 25, 2024

Supplemental Implementation Tools

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

Interventions that lead to earlier liberation from mechanical ventilation can improve patient outcomes. This guideline, a collaborative effort between the American Thoracic Society and the American College of Chest Physicians, provides evidence-based recommendations to optimize liberation from mechanical ventilation in critically ill adults.

Target Patient Population

Critically ill adults

PICO Questions

  1. Should Acutely Hospitalized Adults Who Have Been Mechanically Ventilated for More Than 24 Hours Be Subjected to Protocolized Rehabilitation Directed toward Early Mobilization or No Protocolized Attempts at Early Mobilization?

  2. Should Acutely Hospitalized Adults Who Have Been Mechanically Ventilated for More Than 24 Hours Be Managed with a Ventilator Liberation Protocol or No Protocol?

  3. Should a Cuff Leak Test Be Performed before Extubation of Mechanically Ventilated Adults?

  4. Should Systemic Steroids Be Administered to Adults Who Fail a Cuff Leak Test before Extubation?

Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings

Hospital, Operating and recovery room

Intended Users

Nurse, nurse practitioner, physician, physician assistant

Scope

Management

Diseases/Conditions (MeSH)

D012123 - Pulmonary Ventilation

Keywords

mechanical ventilation

Source Citation

Schmidt GA, et al. Official Executive Summary of an American Thoracic Society / American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. Am J Respir Crit Care Med 2017; 195(1):115-119 and CHEST 2017; 151(1):160–165.

Girard TD, et al. Liberation from Mechanical Ventilation in Critically Ill Adults: An Official American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline. Rehabilitation Protocols, Ventilator Liberation Protocols, and Cuff Leak Tests. Am J Respir Crit Care Med 2017; 195(1):120-133.

Ouellette DR, et al. Liberation from Mechanical Ventilation in Critically Ill Adults: An Official American College of Chest Physicians/American Thoracic Society Clinical Practice Guideline. Inspiratory Pressure Augmentation during Spontaneous Breathing Trials, Protocols Minimizing Sedation, and Non-invasive Ventilation Immediately After Extubation. CHEST 2017; 151(1): 166-180.

Methodology

Number of Source Documents
129
Literature Search Start Date
December 1, 2014
Literature Search End Date
May 1, 2015