Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer
Key Points
Key Points
- It is estimated that there will be 22,530 new cases of ovarian cancer diagnosed in 2019 in the United States and, in spite of advances in treatment, an estimated 13,980 women will die from the disease.
- Ovarian cancer ranks fifth in cancer deaths among women.
- Approximately 25% of all ovarian cancers are caused by a heritable genetic condition.
- Many medical societies recommend genetic testing for all women diagnosed with ovarian cancer, yet only about 30% of women undergo any genetic testing.
Diagnosis
...iagnosi...
....1All women diagnosed with epithelia...
...on 1.2Women diagnosed with clear cell, endom...
...1.3Testing for dMMR may be offered to women d...
...mmendation 1.4Those genetic evaluatio...
...commendation 1.5First- or second-degree blo...
...on 2.1Women diagnosed with epithelial ovarian can...
....2Women diagnosed with recurrent epithelial ovaria...
....3No recommendations can be made suppor...
...2.4Clinical decisions should not be based on a var...
...on 3.1Women with epithelial ovarian...
...tion 3.2Women with epithelial ovarian cancer who...
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