Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer
Publication Date: January 27, 2020
Key Points
Key Points
- It is estimated that there will be 22,530 new cases of ovarian cancer diagnosed in 2019 in the United States and, in spite of advances in treatment, an estimated 13,980 women will die from the disease.
- Ovarian cancer ranks fifth in cancer deaths among women.
- Approximately 25% of all ovarian cancers are caused by a heritable genetic condition.
- Many medical societies recommend genetic testing for all women diagnosed with ovarian cancer, yet only about 30% of women undergo any genetic testing.
Diagnosis
Diagnosis
...n 1.1All women diagnosed with epitheli...
...ndation 1.2Women diagnosed with clear cell, endo...
...ommendation 1.3Testing for dMMR may be off...
...1.4Those genetic evaluations should be conduct...
...endation 1.5First- or second-degree blood relativ...
...endation 2.1Women diagnosed with epit...
...endation 2.2Women diagnosed with recurr...
...2.3No recommendations can be made su...
...dation 2.4Clinical decisions should...
...3.1Women with epithelial ovarian cancer should b...
...ndation 3.2Women with epithelial ovarian can...
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