Biomarkers for Adjuvant Endocrine and Chemotherapy in Early-Stage Breast Cancer
Key Points
Key Points
Diagnosis
...agnosis...
...ER-positive, HER2-negative Breast C...
...(21-gene recurrence score)...
...1.1If a patient has node-negative breast can...
...dation 1.2In the group of patients...
...ecommendation 1.3In the group of patient...
...ion 1.4If a patient is postmenopausal and has nod...
...dation 1.5In the group of patients in Recommend...
...ation 1.6If a patient is premenopa...
...tion 1.7If a patient has node-positive b...
...Print (70-gene signature)...
...commendation 1.8If a patient is older than...
....9If a patient is 50 years of age or younger an...
...dation 1.10If a patient has low clinical...
...1.11If a patient has node-positive breast c...
...dict (12-gene risk score)...
...ion 1.12If a patient is postmenopausal and has...
....13If a patient is premenopausal and has breast...
...ndation 1.14If a patient has breast cancer with mo...
...igna (PAM50)...
...endation 1.15If a patient is postmenopa...
...ion 1.16If a patient is premenopausal, and h...
...tion 1.17If a patient is postmenopausal and has n...
...commendation 1.18If a patient has node-...
...ammostrat
...is insufficient evidence to recommend use of...
...ancer Index (BCI)...
...tient has ER-positive, HER2-negati...
...a patient has ER-positive, HER2-negative, node-p...
Ki6...
...dation 1.19If a patient is postmenopausa...
...dation 1.20If a patient is postmenopausal and ha...
...n 1.21Despite the limitations associated...
...istochemistry 4 (IHC4)...
...on 1.22If a patient has node-negative or node-posi...
...A and PAI-1
...patient has ER-positive, HER2-negati...
...t has HER2-positive breast cancer...
...ne Therapy For ER Receptor-positive HER2-ne...
...e DX, EndoPredict, Prosigna, Ki67, o...
...tion 1.23If a patient has node-negative breas...
BC...
...1.24If a patient has node-negative or node-positi...
...commendation 1.25If a patient has node-positive br...
...nical Treatment Score post-5 Yea...
...1.26If a patient is postmenopausal and ha...
...positive Breast Cancer or TN...
...ncotype DX, EndoPredict, MammaPrint, BCI, Pros...
Recommendation 1.27If a patient has HER2-positive...
...ng Biomarkers...
...nfiltrating Lymphocytes (TILs)...
...ecommendation 1.28If a patient has node-negat...
...D-L1 TestingĀ...
...1.29If a patient has node-negative or node-pos...
...ing Tumor Cells (CTC)
...mendation 1.30If a patient has node-nega...
...ating Tumor DNA (ctDNA)...
...ion 1.31If a patient has node-negative or...
.... Breast Cancer Biomarkers to Guide Adjuvant Th...
...Algorithm on Biomarkers to Guide Decisions on Adj...
...ication of Patients According to Clinical Risk...
...believes that cancer clinical trials are...