Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
Treatment
Oral Cavity
Oropharynx
Recommendation Grading
Overview
Title
Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
Authoring Organization
American Society of Clinical Oncology
Publication Month/Year
February 27, 2019
Last Updated Month/Year
November 11, 2024
Supplemental Implementation Tools
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Document Objectives
The aim of the current work is to provide evidence-based recommendations to practicing physicians and others on the management of the neck in patients with squamous cell carcinoma of the oral cavity and oropharynx.
Target Patient Population
Patients with SCCOC or SCCOP with nodal metastases or who are at risk for nodal metastases.
Target Provider Population
Medical oncologists, radiation oncologists, surgeons, nurses, speech pathologists, oncology pharmacists, and patients
PICO Questions
What are the indications for and the hallmarks of a high-quality neck dissection in oral cavity squamous cell carcinoma (SCCOC)?
Under what circumstances should a dissected neck receive adjuvant radiotherapy or chemoradiotherapy in patients with SCCOC?
Is neck radiotherapy to an undissected clinically node-negative (cN0) neck an adequate replacement for high-quality elective neck dissection in SCCOC?
What are the hallmarks of a high-quality neck dissection in oropharynx squamous cell carcinoma (SCCOP)?
For patients with SCCOP, what features of clinical/radiographic nodal involvement would sway management away from surgery in favor of a nonoperative approach?
Under what circumstances should a patient with SCCOP undergo a neck dissection after definitive radiotherapy or chemoradiotherapy?
Inclusion Criteria
Male, Female, Adult, Older adult
Health Care Settings
Ambulatory, Hospital, Outpatient, Radiology services
Intended Users
Nurse, nurse practitioner, health systems pharmacist, physician, physician assistant, radiology technologist, speech language pathologist
Scope
Treatment, Management
Diseases/Conditions (MeSH)
D002294 - Carcinoma, Squamous Cell, D000077195 - Squamous Cell Carcinoma of Head and Neck
Keywords
head and neck squamous cell carcinoma (HNSCC), squamous cell carcinoma, oropharynx, oral cavity, SCCOC, SCCOP, nodal metastases
Source Citation
DOI: 10.1200/JCO.18.01921 Journal of Clinical Oncology 37, no. 20 (July 10, 2019) 1753-1774.