![American Society of Clinical Oncology American Society of Clinical Oncology](https://54d4f314-8f94-415c-acb7-fd0a6332f070.s3.amazonaws.com/403/403__asco-logo-lg__274272709.png?X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAU2BE4PNFKE2WZV7V%2F20240908%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Date=20240908T001143Z&X-Amz-SignedHeaders=host&X-Amz-Expires=86400&X-Amz-Signature=055fddb781c6231abbf27900f063b2c043747d86c74a8b6afe5b93ed3981f641)
Small Renal Masses
Publication Date: January 17, 2017
Key Points
Key Points
ASCO defines small renal masses (SRMs) as incidentally image-detected, contrast-enhancing renal tumors ≤4 cm in diameter that are usually consistent with stage T1a renal cell carcinoma.
On rare occasions, SRMs may be unusual malignant tumor types such as lymphoma, sarcoma, or a metastasis to the kidney.
More than one imaging modality may be required to confirm that the lesion is solid and/or enhancing.
With more widespread use of axial imaging, usually ordered for nonspecific gastrointestinal or musculoskeletal symptoms, there has been a continued increase in the rate of incidentally detected SRMs.
As many as 25% of SRMs are benign renal cortical tumors (eg, oncocytoma, metanephric adenoma, and angiomyolipoma), and another 25% are indolent in nature with limited metastatic potential (eg, chromophobe, type 1 papillary renal cancer).
On rare occasions, SRMs may be unusual malignant tumor types such as lymphoma, sarcoma, or a metastasis to the kidney.
More than one imaging modality may be required to confirm that the lesion is solid and/or enhancing.
With more widespread use of axial imaging, usually ordered for nonspecific gastrointestinal or musculoskeletal symptoms, there has been a continued increase in the rate of incidentally detected SRMs.
As many as 25% of SRMs are benign renal cortical tumors (eg, oncocytoma, metanephric adenoma, and angiomyolipoma), and another 25% are indolent in nature with limited metastatic potential (eg, chromophobe, type 1 papillary renal cancer).
- Although certain renal tumor histologies have distinct imaging characteristics, current radiologic imaging cannot reliably discriminate benign from indolent or potentially malignant tumors. In addition to the diagnostic dilemma, the natural history of these lesions is variable, and many tumors demonstrate an indolent course.
Diagnosis
Diagnosi...
...is of tumor-specific findings and compet...
...e surveillance should be an initial mana...
Treatment
...eatment
...nephrectomy (PN) for SRMs is the standard treatme...
...thermal ablation should be considere...
...ephrectomy for SRMs should be reserved o...
...ferral to a nephrologist should be considered...
Figure 1. Management of Small Renal Masses
Figure 1. Management of Small Renal M...