Cervical Cancer Prevention
Key Points
Key Points
- Vaccination is the optimal strategy for primary prevention of infection by some types of human papillomavirus that cause cervical cancer in the target population. There is no other preventive strategy for this cancer that can substitute for vaccination.
- There are three prophylactic HPV vaccines approved and recommended in the United States, Europe, and many regions and countries: the bivalent (2vHPV; against HPV 16 and 18), quadrivalent (4vHPV; against HPV 6, 11, 16, and 18), and nine valent (9vHPV; against HPV 6, 11, 16, 18, 31, 33, 45, 52 and 58)
- NOTE: Gardasil-9 (9-valent HPV vaccine) will be the only HPV vaccine available in the United States after May 2017. Source: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/hpv.html.
- As a partial result of failures within different health care systems at both levels of prevention—vaccination, screening—and disease treatment/management, there are large regional and global disparities in cervical cancer incidence and mortality. Consequently ASCO has established a process for resource-stratified guidelines.
Prevention
...reventi...
...amework of Resource Stratification: Primary Preven...
In Maximal And Enhanced Resource Settings
...And Enhanced Resource Settings...
...health authorities, ministries of heal...
...ealth authorities may set the upper en...
...–14 years of age who are immune compe...
...months ( EB , H , S )614...
...e up to 12–15 months ( EB , L ,...
...rs of age at the time of the first...
...o have received one dose and are >...
...en there is low vaccine coverage o...
...e coverage of girls is ≥50%, then vac...
In Limited Resource Settings
...ted Resource Settings...
...blic health authorities, ministries of health, an...
...ting at 9 years of age who are immune comp...
...t 6 months ( EB , H , S )614...
...–15 months ( EB , L , M )614...
...there are sufficient resources rema...
...of cervical cancer in limited resource settings...
In Basic Settings
...n Basic Setti...
...uthorities, ministries of health, an...
...tarting at 9 years of age who are immune comp...
...east 6 months ( EB , H , S )61...
may be up to 12–15 months. ( E...
...h coverage of priority populations shou...
...n of cervical cancer in basic resource s...
In All Resource Settings
...l Resource Settings...
...who are HIV positive or immunosuppressed for...
...n is NOT recommended for pregnant wome...
...on strategy is recommended for women r...
...dditional Qualifying Statements: If boys are v...