Cervical Cancer Prevention
Key Points
Key Points
- Vaccination is the optimal strategy for primary prevention of infection by some types of human papillomavirus that cause cervical cancer in the target population. There is no other preventive strategy for this cancer that can substitute for vaccination.
- There are three prophylactic HPV vaccines approved and recommended in the United States, Europe, and many regions and countries: the bivalent (2vHPV; against HPV 16 and 18), quadrivalent (4vHPV; against HPV 6, 11, 16, and 18), and nine valent (9vHPV; against HPV 6, 11, 16, 18, 31, 33, 45, 52 and 58)
- NOTE: Gardasil-9 (9-valent HPV vaccine) will be the only HPV vaccine available in the United States after May 2017. Source: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/hpv.html.
- As a partial result of failures within different health care systems at both levels of prevention—vaccination, screening—and disease treatment/management, there are large regional and global disparities in cervical cancer incidence and mortality. Consequently ASCO has established a process for resource-stratified guidelines.
Prevention
Preventi...
...of Resource Stratification: Primary...
In Maximal And Enhanced Resource Settings
...aximal And Enhanced Resource Set...
...lic health authorities, ministries of healt...
...alth authorities may set the upper end of the targ...
...€“14 years of age who are immune competen...
...east 6 months ( EB , H , S )6...
...e up to 12–15 months ( EB , L , W )...
...≥15 years of age at the time of the f...
...o have received one dose and are >14...
...hen there is low vaccine coverage of the...
...coverage of girls is ≥50%, then va...
In Limited Resource Settings
...Limited Resource Set...
...authorities, ministries of health, and prim...
...starting at 9 years of age who are immune compet...
...st 6 months ( EB , H , S )...
...be up to 12–15 months ( EB , L ,...
...are sufficient resources remaining after v...
...prevention of cervical cancer in lim...
In Basic Settings
...sic Settings...
...health authorities, ministries of hea...
...r girls starting at 9 years of age who are imm...
...least 6 months ( EB , H ,...
...e up to 12–15 months. ( EB , L , M )61...
...rage of priority populations should be em...
...r prevention of cervical cancer in basic res...
In All Resource Settings
...All Resource Se...
...les who are HIV positive or immunosup...
...PV vaccination is NOT recommended for pre...
...n strategy is recommended for women recei...
...ional Qualifying Statements: If boys are...