Acute Pancreatitis
Publication Date: March 1, 2018
Key Points
Key Points
- Acute pancreatitis (AP) is an inflammatory condition of the pancreas that can cause local injury, systemic inflammatory response syndrome (SIRS) and organ failure.
- The incidence of AP ranges from 5–30 cases per 100,000, and there is evidence that the incidence is rising in recent years.
- The overall case fatality rate for AP is roughly 5% and is expectedly higher for more severe disease.
- The most common causes of AP remain gallstones and alcohol, which together comprise 80% of cases. The remainder of cases is due to less common causes, including drug reactions, pancreatic solid and cystic malignancies, and hypertriglyceridemia.
- Patients with AP frequently suffer from abdominal pain, nausea, and vomiting.
- The diagnosis of AP requires ≥2 of the following features:
- Characteristic abdominal pain
- Biochemical evidence of pancreatitis (i.e. amylase or lipase elevated >3 times the upper limit of normal) and/or
- Radiographic evidence of pancreatitis on cross-sectional imaging
Treatment
Treatment
...f Recommendations of the AGA Clinical Guideli...
...ients with acute pancreatitis, AGA suggests using...
...patients with acute pancreatitis, AGA suggests ag...
...patients with predicted severe acute p...
...ith acute biliary pancreatitis and no chola...
In patients with acute pancreatiti...
...ith acute pancreatitis and inabilit...
...ients with predicted severe or necrotizing pa...
...atients with acute biliary pancreati...
...ith acute alcoholic pancreatitis, AGA recommends...