Title

Interactions Between Anti‐Infective Agents And Immunosuppressants

Authoring Organization

American Society of Transplantation

Publication Month/Year

April 1, 2019

Last Updated Month/Year

December 2, 2022

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation provide an update on potential drug‐drug interactions between anti‐infectives and immunosuppressants, which are most notable with calcineurin and mTOR inhibitors. 

Target Patient Population

Patients receiving immunosuppressants require antimicrobial therapy

Inclusion Criteria

Female, Male, Adolescent, Adult, Older adult

Health Care Settings

Ambulatory, Hospital, Long term care, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant

Scope

Assessment and screening, Management

Diseases/Conditions (MeSH)

D014180 - Transplantation, D007165 - Immunosuppression, D007166 - Immunosuppressive Agents, D004347 - Drug Interactions, D000898 - Antibiosis, D000935 - Antifungal Agents

Keywords

antifungal, solid organ transplant, immunosuppressant, antimicrobial, drug interactions

Source Citation

Clinical Transplantation. 2019;33:e13510.
https://doi.org/10.1111/ctr.13510