Adenovirus In Solid Organ Transplant Recipients
Recommendations
DIAGNOSTIC STRATEGIES
Immunohistochemical staining for adenovirus may be useful to distinguish infection from rejection.
TREATMENT
- Hyperhydration
- and probenecid
should be administered to minimize the risk of nephrotoxicity. The ideal dose and frequency of cidofovir administration is not known.
PREVENTION
Recommendation Grading
Overview
Title
Adenovirus In Solid Organ Transplant Recipients
Authoring Organization
American Society of Transplantation
Publication Month/Year
April 1, 2019
Last Updated Month/Year
December 2, 2022
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Document Objectives
These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation review the diagnosis, prevention, and management of adenovirus infections after solid organ transplantation.
Target Patient Population
Solid organ transplant patients
Inclusion Criteria
Female, Male, Adolescent, Adult, Older adult
Health Care Settings
Ambulatory, Hospital, Operating and recovery room, Outpatient
Intended Users
Nurse, nurse practitioner, physician, physician assistant
Scope
Diagnosis, Prevention, Management, Treatment
Diseases/Conditions (MeSH)
D014180 - Transplantation, D019737 - Transplants, D000998 - Antiviral Agents, D016377 - Organ Transplantation, D000260 - Adenoviruses, Human, D000257 - Adenoviridae Infections
Keywords
antiviral, prevention, infection, solid organ transplant, adenovirus
Source Citation
Florescu, DF, Schaenman, JM; on behalf of the AST Infectious Diseases Community of Practice. Adenovirus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019; 33:e13527.