Top Ophthalmology Articles – Guidelines+ Journals Rundown

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In this post, we will be taking a closer look at some of the most popular ophthalmology-related articles recently published across medical journals.

Combining Paracentral Acute Middle Maculopathy and Peripapillary Fluid as Biomarkers in Anterior Ischemic Optic Neuropathy

  • American Journal of Ophthalmology
  • December 2024
  • The researchers are conducted a study to investigate whether paracentral acute middle maculopathy (PAMM) and peripapillary intraretinal and subretinal fluid (IRF/SRF) can be utilized as distinguishing factors between arteritic anterior ischemic optic neuropathy (A-AION) and nonarteritic AION (NA-AION) in the early stages.
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Five-Year Outcomes of Lenadogene Nolparvovec Gene Therapy in Leber Hereditary Optic Neuropathy

  • JAMA Ophthalmology
  • December 2024
  • There have been few studies conducted to evaluate the long-term benefits and risks of gene therapy for Leber hereditary optic neuropathy (LHON). The objective of this study is to assess the safety and effectiveness of lenadogene nolparvovec in patients with LHON caused by the MT-ND4 gene variant for a period of up to 5 years following treatment.
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3-year Outcomes of Botulinum Toxin versus Strabismus Surgery for the Treatment of Acute Acquired Comitant Esotropia in Children

  • American Journal of Ophthalmology
  • January 2025
  • Botulinum toxin presents itself as a viable alternative to traditional strabismus surgery in the treatment of acute, acquired, comitant esotropia (AACE). Past research indicates that both treatment methods may yield comparable results for up to 6 months. The objective of this study was to ascertain whether botulinum toxin maintains its efficacy in comparison to strabismus surgery over a 36-month period post-treatment..
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Empagliflozin and the Risk of Retinopathy in Patients With Type 2 Diabetes

  • JAMA Ophthalmology
  • December 2024
  • Empagliflozin has shown promise in potentially reducing the risk of diabetic retinopathy (DR) by preventing the loss of retinal pericytes. However, the specific impact of empagliflozin on DR in patients with type 2 diabetes (T2D) is still not fully understood. The objective of this study is to compare the risk of developing nonproliferative DR (NPDR) and the progression of DR in patients with T2D who are starting treatment with empagliflozin versus a dipeptidyl peptidase 4 inhibitor (DPP4i). This research aims to provide valuable insights into the potential benefits of empagliflozin in managing DR in patients with T2D.
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Evaluating glaucoma in myopic eyes: Challenges and opportunities

  • Survey of Ophthalmology
  • December 2024
  • The researchers comprehensively examine the challenges encountered in evaluating glaucoma in myopic eyes through various diagnostic tools, including fundus photography, OCT of the ONH, retinal nerve fiber layer, and macular ganglion cell layer, OCTA, and perimetry. They also explore potential opportunities to address these challenges, providing insights for clinicians to effectively manage myopic glaucoma patients in clinical practice.
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Biosimilar Candidate CT-P42 in Diabetic Macular Edema: 24-Week Results from a Randomized, Active-Controlled, Phase III Study

  • Ophthalmology Retina
  • December 2024
  • The purpose of this study is to demonstrate the therapeutic equivalence of CT-P42 in comparison to the reference drug aflibercept (Eylea) for the treatment of diabetic macular edema (DME) in adult patients.
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A Systematic Review Assessing the Quality of Patient Reported Outcome Measures in Ocular Surface Disease

  • The Ocular Surface
  • January 2025
  • The aim of this study is to identify and evaluate the quality of validated patient-reported outcome measures (PROMs) currently utilized for assessing the impact of ocular surface diseases (OSDs) on quality of life (QoL).
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Three-Month Clinical Outcomes to Correct Myopia or Myopic Astigmatism Using a Femtosecond Laser for Lenticule Creation With Automated Centration and Cyclotorsion Compensation

  • Journal of Refractive Surgery
  • January 2025
  • The objective is to assess the clinical outcomes of laser-assisted lenticule extraction for myopia and myopic astigmatism in the first three months post-surgery, specifically focusing on the results for the right and left eyes. This evaluation will be conducted using the innovative ATOS femtosecond laser system (Smart-Sight; SCHWIND eye-tech-solutions).
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Surgeon Adoption of Immediate Sequential Bilateral Cataract Surgery in the United States from 2018 to 2022 Immediate Sequential Bilateral Cataract Surgery

  • Journal of Cataract and Refractive Surgery
  • January 2025
  • The objective of this study is to analyze the 5-year trends in the rate of immediate sequential bilateral cataract surgery (ISBCS) and identify the surgeon characteristics that are associated with performing ISBCS.
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