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Guidelines+ Trials Spotlight - TROPION-Lung01 Phase III trial

EGFR-Mutated NSCLC (The TROPION-Lung01 Phase III Trial) – Guidelines+ Trials Spotlight

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AstraZeneca and Daiichi Sankyo have collaboratively submitted a new Biologics License Application (BLA) for accelerated approval in the United States for datopotamab deruxtecan (Dato-DXd). This application aims to provide treatment for adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated (EGFR) non-small cell lung cancer (NSCLC) who have previously undergone systemic therapies, including […]

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Focus
Clinical Trials
Specialties
Oncology • Pulmonology
ASH 2024 Conference Recap - Bleeding & Clotting Disorders

2024 ASH Annual Meeting and Exposition – Conference Recap on Bleeding & Clotting Disorders

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The 66th ASH Annual Meeting and Exposition took place from December 7-10, 2024, in San Diego, California, as well as online. This event is the premier hematology gathering of the year, attracting over 30,000 health professionals, clinicians, researchers, educators, and other industry experts. Attendees can expect a multitude of sessions, thousands of abstracts, and numerous […]

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Focus
Conferences
Specialties
Hematology
Guidelines Spotlight Diagnosis & Management of Myocarditis

ACC’s Guidance for the Diagnosis & Management of Myocarditis – Guidelines Spotlight

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The American College of Cardiology (ACC) has recently released guidance for diagnosing and treating acute myocarditis in adult patients. The 2024 ACC Expert Consensus Decision Pathway (ECDP) on Strategies and Criteria for the Diagnosis and Management of Myocarditis outlines a 5-step care pathway, along with recommendations for resuming strenuous physical activity. Additionally, the guidelines aim […]

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Focus
Guidelines
Specialties
Cardiology
Guideline Timeline - Restless Leg Syndrome

Restless Leg Syndrome – Guidelines Timeline

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Restless Legs Syndrome (RLS), also known as Willis-Ekbom Disease, primary RLS, and idiopathic RLS, is a neurological disorder characterized by unpleasant sensations in the legs and an irresistible urge to move them. The Centers for Disease Control (CDC) estimates that up to 7-10% of the US population may be affected by RLS, with onset possible […]

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Focus
Guidelines
Specialties
Internal Medicine - General • Neurology • Pulmonology • Sleep Medicine
Guidelines Spotlight Diabetes Standards of Care (2025)

Diabetes Standards of Care (2025) – Guidelines Spotlight

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Welcome to the latest edition of our Guideline Spotlight, where we will explore the valuable insights and key takeaways from the most recent guideline releases. Today, our focus is on the American Diabetes Association’s (ADA) latest edition of their Standards of Care in Diabetes, which was released on December 9, 2024. This edition consolidates all […]

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Focus
Guidelines
Specialties
Endocrinology • Diabetology

AUA Seeks Peer Reviewers for Upcoming Vasectomy Guideline

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The American Urological Association (AUA) is currently seeking feedback and comments on their draft vasectomy guideline. AUA members and other interested parties will have the opportunity to review the draft guideline starting in January 2025, for a period of approximately two weeks. Prior to receiving a copy of the draft guideline, all reviewers must disclose […]

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Focus
Guidelines
Specialties
Urology

USPSTF’s Cervical Cancer Screening Recommendation is Now Open for Public Comment

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The United States Preventive Services Task Force (USPSTF) recently released their draft recommendation statement titled Cervical Cancer: Screening, which was published online on December 10, 2024. This recommendation serves as an update to the previous 2018 guideline. The latest draft remains consistent with the 2018 recommendation but includes a new recommendation. It now suggests that […]

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Focus
Guidelines
Specialties
Internal Medicine - General • Obstetrics and Gynecology • Oncology • Preventive Medicine • Public Health and General Preventive Medicine
Guidelines+ Trials Spotlight - Metastatic Squamous Cell Carcinoma of the Head & Neck (STELLAR-305)

Metastatic Squamous Cell Carcinoma of the Head and Neck (STELLAR-305) – Guidelines+ Trials Spotlight

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One year ago, Exelixis commenced their phase 2/3 pivotal trial to assess the efficacy of zanzalintinib in combination with pembrolizumab compared to pembrolizumab alone in patients with previously untreated PD-L1-positive recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN). Zanzalintinib, an oral drug developed by Exelixis, targets and inhibits receptor tyrosine kinases […]

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Focus
Clinical Trials
Specialties
Oncology

Baloxavir Marboxil (Xofluza/Genetech) – Guidelines+ Monographs

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In recognition of National Influenza Vaccination Week (NIVW), our latest edition of the Guidelines+ Monographs Series will delve into the medication baloxavir marboxil, marketed under the brand name Xofluza®  by Genentech. Xofluza is an influenza virus polymerase acidic (PA) endonuclease inhibitor indicated for the treatment of acute uncomplicated influenza in patients 5 years of age […]

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Focus
Medications
Specialties
Family Medicine • Infectious Diseases • Infectious Disease • Internal Medicine - General • Pediatrics • Adolescent Medicine • Pediatric Infectious Diseases • Public Health and General Preventive Medicine
Guidelines + Trials Rundown Thalassemia

Thalassemia in Adults – Guidelines+ Trials Rundown

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Today, we will be looking into the latest research and clinical trials focused on thalassemia in adults. The following list has been carefully curated by evaluating the ongoing phase 3 trials for thalassemia, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This compilation primarily […]

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Focus
Clinical Trials
Specialties
Family Medicine • Hematology • Pediatrics • Adolescent Medicine • Pediatric Hematology/Oncology