A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy in Patients With Microhematuria: The Safe Testing of Risk for Asymptomatic Microhematuria Trial.

Publication Date: 2024 Jul


Full Text Sources

Atypon

Ovid Technologies, Inc.

Wolters Kluwer

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Authors

Yair Lotan; Siamak Daneshmand; Neal Shore; Peter Black; Kristen R Scarpato; Amit Patel; Tony Lough; Daniel A Shoskes; Jay D Raman

Abstract

OBJECTIVE

AUA guidelines for patients with microhematuria (≥3 red blood cells [RBC]/high-power field [hpf]) include cystoscopy for most over age 40 due to risk of urothelial cancer (UC). Cxbladder Triage (CxbT) is a urinary genomic test with UC negative predictive value of 99%. In this prospective randomized controlled trial, we compared cystoscopy use in a standard of care (SOC) arm vs a marker-based approach.


Source

The Journal of urology


Pub Types(s)

Journal Article


Language

English


PubMed ID

38700731