Associations Between Self and Study Partner Report of Cognitive Decline With Regional Tau in a Multicohort Study. Journal Abstract

Associations Between Self and Study Partner Report of Cognitive Decline With Regional Tau in a Multicohort Study.

Publication Date: 2024 Jun 25

Full Text Sources

Authors

Michalina F Jadick; Talia Robinson; Michelle E Farrell; Hannah Klinger; Rachel F Buckley; Gad A Marshall; Patrizia Vannini; Dorene M Rentz; Keith A Johnson; Reisa A Sperling; Rebecca E Amariglio

Abstract

OBJECTIVE

Self-reported cognitive decline is an early behavioral manifestation of Alzheimer disease (AD) at the preclinical stage, often believed to precede concerns reported by a study partner. Previous work shows cross-sectional associations with β-amyloid (Aβ) status and self-reported and study partner-reported cognitive decline, but less is known about their associations with tau deposition, particularly among those with preclinical AD.

Source

Neurology

Pub Types(s)

Journal Article

Language

English

PubMed ID

38810211