Vitamin D deficiency: A forgotten aspect in sleep disorders? A critical update. Journal Abstract

Vitamin D deficiency: A forgotten aspect in sleep disorders? A critical update.

Publication Date: 2024 Sep

Full Text Sources

Elsevier Science

ClinicalKey

Authors

Sophia Schiza; Izolde Bouloukaki; Athanasios Kaditis; Carolina Lombardi; Maria R Bonsignore

Abstract

OBJECTIVE

Over the past few years, there has been a surge in interest regarding the connection between sleep duration and quality, sleep disorders, mainly Obstructive sleep apnoea (OSA) and Vitamin D. There is growing evidence to support a new role of Vitamin D in the maintenance and regulation of optimal sleep. Furthermore, a notable link has been identified between OSA and a decrease in serum Vitamin D levels, which appears to intensify as the severity of sleep apnea worsens. Vitamin D status could also potentially serve as a mediator or provide an explanation for the association between OSA and cardiometabolic morbidity, but the current state of research in this area is inadequate. Studies have indicated that the supplementation of Vitamin D can optimize sleep quality, presenting more proof of the connection between insufficient vitamin D levels and sleep disorders. However, it is unclear whether low serum Vitamin D levels are a contributing factor to OSA development or if OSA predisposes individuals to Vitamin D deficiency. As a result, various studies have endeavored to examine the complex relationship between OSA and Vitamin D deficiency. In children and adolescents, while data is limited, there seems also to be a link between sleep disorders and Vitamin D levels. Therefore, the objective of this review is to provide a comprehensive overview of the current evidence on the association between Vitamin D and sleep disorders in both adults and children.

Source

Sleep medicine

Pub Types(s)

Journal Article

Language

English

PubMed ID

38941960