Upper Gastrointestinal Mucosal Damage and Subsequent Risk of Parkinson Disease.

Publication Date: 2024 Sep 03


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Authors

Jocelyn J Chang; Subhash Kulkarni; Trisha S Pasricha

Abstract

OBJECTIVE

The gut-first hypothesis of Parkinson disease (PD) has gained traction, yet potential inciting events triggering Parkinson pathology from gut-related factors remain unclear. While Helicobacter pylori infection is linked to mucosal damage (MD) and PD, it is unknown how upper gastrointestinal MD from any source increases PD risk.


Source

JAMA network open


Pub Types(s)

Journal Article


Language

English


PubMed ID

39235810