Role of the X Chromosome in Alzheimer Disease Genetics. Journal Abstract

Role of the X Chromosome in Alzheimer Disease Genetics.

Publication Date: 2024 Oct 01

Full Text Sources

Authors

Michael E Belloy; Yann Le Guen; Ilaria Stewart; Kennedy Williams; Joachim Herz; Richard Sherva; Rui Zhang; Victoria Merritt; Matthew S Panizzon; Richard L Hauger; J Michael Gaziano; Mark Logue; Valerio Napolioni; Michael D Greicius

Abstract

OBJECTIVE

The X chromosome has remained enigmatic in Alzheimer disease (AD), yet it makes up 5% of the genome and carries a high proportion of genes expressed in the brain, making it particularly appealing as a potential source of unexplored genetic variation in AD.

Source

JAMA neurology

Pub Types(s)

Journal Article

Language

English

PubMed ID

39250132