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Clinical Practice Guidelines

ACR 2024 Recap

ACR Convergence 2024 – Conference Recap on Gout

The American College of Rheumatology’s annual meeting, ACR Convergence 2024, was held from November 14 to 19 at the Walter E. Washington Convention Center in Washington, D.C. This prestigious event brought together leading experts in the field to exchange the latest advancements in rheumatology. At ACR Convergence 2024, several significant abstracts were presented focusing on […]

BAD Int'l Guidelines

British Association of Dermatologists (BAD) – Guidelines International Series

In this installment of our Guidelines International Series, we delve into the rich history of the British Association of Dermatologists (BAD), a venerable society established in 1919 by Sir Archibald Gray, then Editor of the British Journal of Dermatology. The BAD’s guiding principle, ‘healthy skin for all’, remains the cornerstone of their mission, although it […]

Guideline Timeline - Ulcerative Colitis Management

Ulcerative Colitis Management – Guidelines Timeline

Ulcerative colitis (UC) impacts nearly 2 million individuals in the United States. This chronic inflammatory bowel disease typically emerges in early adulthood and follows a pattern of relapsing and remitting symptoms. Unfortunately, up to 20% of patients may eventually require colectomy, and 33% may need hospitalization for disease management. Effectively controlling inflammatory activity is essential […]

AHA 2024 Conference Recap - Hypertension

AHA24 – Conference Recap on Hypertension

The American Heart Association’s (AHA) annual meeting, AHA24, was held from November 16-18, 2024, at the McCormick Place Convention Center in Chicago, Illinois. This prestigious event serves as the premier global platform for showcasing the latest advancements in cardiovascular science and medicine, providing attendees with the opportunity to engage with cutting-edge research and practice-changing educational […]

Guidelines+ Trials Spotlight - Kisqali HR+HER2 Early Breast Cancer Results (NATALEE)

Kisqali HR+/HER2- Early Breast Cancer Results (NATALEE) – Guidelines+ Trials Spotlight

On September 17, 2024, the US Food and Drug Administration (FDA) granted approval for Novartis’s Kisqali® (ribociclib) in combination with an aromatase inhibitor (AI) for the adjuvant treatment of individuals with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) stage II and III early cancer (EBC) at high risk of recurrence, including those with node-negative […]

ASCO’s Thyroid Cancer Guideline is Now Open for Public Comment

The American Society of Clinical Oncology (ASCO) has announced that the following guideline, “Systemic Treatment of Thyroid Cancer” is now open for public comment.  This latest guideline incorporates new evidence to ensure the most current recommendations are provided. As part of ASCO’s development process, they invite reviews and feedback for a 2-to-3-week period. Interested parties […]

Guidelines Rundown - COPD

Chronic Obstructive Pulmonary Disease (COPD) – Guidelines Rundown (COPD Awareness Month)

Our Guidelines Rundown Series persists with a fresh article delving into the topic of chronic obstructive pulmonary disease (COPD) in recognition of COPD Awareness Month 2024. To aid in clinical decision-making, numerous societies have published extensive guidelines addressing different facets of COPD, such as nutrition management, COPD exacerbations, home oxygen therapy, and more. This article […]

Guidelines Rundown - Non-Cancer Bladder Health

Non-Cancer Bladder Health – Guidelines Rundown (Bladder Health Awareness Month)

The Urology Care Foundation, the official Foundation of the American Urological Association (AUA), is utilizing the month of November to address the stigma surrounding bladder health issues. Our goal is to provide resources that raise awareness and facilitate conversations between patients and their healthcare providers. In support of Bladder Health Awareness Month 2024, this edition […]

What's Changed Epilepsy

Epilepsy – What’s Changed

Each November, we commemorate National Epilepsy Awareness Month (NEAM), focusing on educating the public about epilepsy symptoms and supporting research efforts. In honor of NEAM, today’s article will focus on epilepsy. According to the Centers for Disease Control (CDC), between 2021 and 2022, approximately 2.9 million adults aged 18 and older reported experiencing active epilepsy, […]

Guideline Timeline - Stage IV NSCLC Without Driver Alterations

Stage IV NSCLC Without Driver Alterations – Guidelines Timeline

In the most recent edition of our Guidelines Timeline Series, we explore the American Society of Clinical Oncology’s (ASCO) guideline on Stage IV Non-Small Cell Lung Cancer without Driver Alterations, which was published on February 28, 2024. This guideline was introduced by ASCO as a living document, that is continuously updated to reflect the latest […]

Guidelines Side-By-Side Prostate Cancer

Comparing Prostate Cancer Guidelines – Guidelines Side-By-Side

Prostate cancer continues to be the most prevalent non-cutaneous cancer among men in the United States (US), with an estimated 268,490 new cases and 34,500 deaths projected for 2022. Given that the majority of newly diagnosed prostate cancer patients present with localized disease, it is crucial to provide evidence-based guideline statements to guide clinical decision-making […]

Guidelines Spotlight Gastropancreatic Neuroendocrine Tumors

Gastroenteropancreatic Neuroendocrine Tumors – Guidelines Spotlight

In this edition of our Guideline Spotlight, we will explore the key insights and takeaways from the American Society of Clinical Oncology’s (ASCO) comprehensive guideline, Systemic Therapy for Tumor Control in Metastatic Well-differentiated Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs). This guideline offers evidence-based recommendations for the treatment of advanced or metastatic GEP-NETs, a rare group of tumors […]

Guidelines Rundown - Epilepsy

Epilepsy – Guidelines Rundown (Epilepsy Awareness Month)

November is National Epilepsy Awareness Month (NEAM), a time dedicated to raising awareness about epilepsy and supporting research efforts. In honor of NEAM, our Guidelines Rundown Series presents a new article focusing on epilepsy. Epilepsy is a well-known condition that affects 1% of adults in the United States. According to the Centers for Disease Control […]

Fluticasone Furoate, Umeclidinium, & Vilanterol Inhalation Powder (Trelegy Ellipta/GSK) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication fluticasone furoate, umeclidinium, and vilanterol, marketed under the brand name Trelegy Ellipta by GlaxoSmithKline. Trelegy Ellipta is a combination of fluticasone furoate, an inhaled corticosteroid (ICS); umeclidinium, an anticholinergic; and vilanterol, a long-acting beta2-adrenergic agonist (LABA) indicated […]

Guidelines Rundown - Premature Birth

Premature Birth – Guidelines Rundown (National Prematurity Awareness Month)

November is recognized as National Prematurity Awareness Month, with World Prematurity Day being observed annually on November 17th to raise awareness about preterm birth. The incidence of preterm birth is increasing globally, with an estimated 15 million infants born preterm each year (more than 3 weeks early), as reported by the World Health Organization (WHO). […]

SCAI’s Guideline for the Management of Chronic Venous Disease is Now Open for Public Comment

The Society for Cardiovascular Angiography and Interventions (SCAI) has announced that the latest draft of the Clinical Practice Guidelines for the Management of Chronic Venous Disease is now available for public comment.  Chronic Venous Disease (CVD) is a condition that is often overlooked by healthcare providers, yet it can have a significant impact on patients’ […]

What's Changed Dravet Syndrome

Dravet Syndrome Guidelines – What’s Changed

Dravet syndrome is a rare form of epilepsy that typically manifests in infancy or early childhood. According to the National Institutes of Health (NIH), initial symptoms often present as either focal or generalized convulsive seizures that begin before the age of 15 months, with many cases occurring before the age of one. These initial seizures […]

Canadian Coalition for Seniors’ Mental Health (CCSMH) Int'l Guidelines

Canadian Coalition for Seniors’ Mental Health (CCSMH) – Guidelines International Series

In this installment of our Guidelines International Series, we will delve into the guidelines established by the Canadian Coalition for Seniors’ Mental Health (CCSMH). The CCSMH is committed to enhancing the quality of care and support for older adults throughout Canada. Their primary focus is on bridging gaps in knowledge and practice to ensure that […]

Guidelines Spotlight Non-Muscle Invasive Bladder Cancer

Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer – Guidelines Spotlight (Bladder Health Awareness Month)

In the United States, it is estimated that there will be 83,190 new cases of bladder cancer and 16,840 bladder cancer-related deaths in 2024. Approximately 25% of newly diagnosed patients are found to have muscle-invasive disease, a statistic that has remained relatively unchanged over the past decade according to data from the Surveillance, Epidemiology, and […]

What's Changed Prurigo Nodularis

Prurigo Nodularis – What’s Changed

Prurigo nodularis is a chronic skin condition that impacts an estimated 75,000 individuals in the United States (US). This condition is characterized by persistent and intense itching, significantly impacting the quality of life for those affected. Research has shown a higher prevalence of prurigo nodularis among individuals with certain comorbidities, such as mental health, endocrine, […]

Guidelines Side-By-Side Chronic Constipation

Comparing Chronic Constipation Guidelines – Guidelines Side-By-Side

Constipation is a prevalent gastrointestinal disorder, affecting approximately 15% of the global population. It is more commonly diagnosed in North America and Europe compared to Asia, likely due to variations in diet, culture, and environment. Risk factors for constipation include age over 65, female gender, sedentary lifestyle, low socioeconomic status, low-fiber diet, and non-White race. […]

ATA 2024 Conference Recap - Thyroid Eye Disease

ATA 2024 – Conference Recap on Thyroid Eye Disease (TED)

The 2024 American Thyroid Association (ATA) Annual Meeting took place from October 30 to November 3 in Chicago, IL. This event is globally recognized as the premier gathering for individuals interested in thyroid diseases and disorders. Attendees had the opportunity to engage in peer-to-peer learning and collaboration through a variety of activities including lectures, interactive […]

Aflibercept (Eylea/Regeneron) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication aflibercept, marketed under the brand name Eylea by Regeneron Pharmaceuticals, Inc. Eylea a is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (Wet) Age-Related Macular Degeneration (AMD), Macular Edema […]

Guidelines Rundown - Bladder Cancer

Bladder Cancer – Guidelines Rundown (Bladder Health Awareness Month 2024)

Welcome to the latest edition of our Guidelines Rundown Series, where we shine a spotlight on the most recent bladder cancer guidelines in recognition of Bladder Health Awareness Month 2024. Multiple medical societies have recently published comprehensive guidelines aimed at assisting healthcare professionals in making informed clinical decisions regarding the diagnosis and treatment of bladder […]

KDIGO’s Anemia in Chronic Kidney Disease Guideline is Now Open for Public Comment

Kidney Disease: Improving Global Outcomes (KDIGO) has announced that the latest draft of the Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD) is now available for public comment. This guideline is designed to educate and provide comprehensive guidance to healthcare professionals on diagnosing, evaluating, and treating anemia in adults and children with CKD, […]