Guideline Central Blog

Clinical Trials

Guidelines+ Trials Spotlight - Kisqali HR+HER2 Early Breast Cancer Results (NATALEE)

Kisqali HR+/HER2- Early Breast Cancer Results (NATALEE) – Guidelines+ Trials Spotlight

On September 17, 2024, the US Food and Drug Administration (FDA) granted approval for Novartis’s Kisqali® (ribociclib) in combination with an aromatase inhibitor (AI) for the adjuvant treatment of individuals with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) stage II and III early cancer (EBC) at high risk of recurrence, including those with node-negative […]

Guidelines + Trials Rundown Actinic Keratosis

Actinic Keratosis in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on actinic keratosis in adults. The following list has been carefully curated by evaluating the ongoing phase 3 trials for actinic keratosis, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This […]

Guidelines + Trials Rundown Urinary Tract Infection (UTI)

Urinary Tract Infection (UTI) in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on both uncomplicated and complicated urinary tract infections (UTIs) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for UTI, specifically targeting adults in the United States. Please note that the dates provided are approximate […]

Guidelines + Trials Rundown: Advanced Hepatocellular Carcinoma (HCC) in Adults

Advanced Hepatocellular Carcinoma (HCC) in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on advanced hepatocellular carcinoma (HCC) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for HCC, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. […]

Guidelines + Trials Rundown Ménière's Disease

Clinical Studies for Ménière’s Disease – Guidelines+ Trials Rundown

Ménière’s disease is a chronic inner ear disorder that affects balance and hearing, often causing vertigo, tinnitus, and hearing loss. While its exact cause remains unclear, the condition can significantly impact quality of life, prompting ongoing research to better understand and manage it. Over the years, various clinical trials have been conducted to explore potential […]

Guidelines + Trials Rundown Ovarian Cancer

Ovarian Cancer in Adults – Guidelines+ Trials Rundown (Ovarian Cancer Awareness Month 2024)

This Ovarian Cancer Awareness Month 2024, we will be looking into the latest research and clinical trials focused on ovarian cancer in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for ovarian cancer, specifically targeting adults in the United States. Please note that the dates provided are approximate […]

Guidelines+ Trials Spotlight - ITRAILBLAZER-ALZ 2

TRAILBLAZER-ALZ 2 Topline Results for the Treatment of Alzheimer’s Disease – Guidelines+ Trials Spotlight

On July 2, 2024, the US Food and Drug Administration (FDA) granted approval for Eli Lilly’s Kisunla (donanemab-azbt) injection for the treatment of Alzheimer’s disease. This treatment is recommended for patients in the early stages of the disease, specifically those with mild cognitive impairment or mild dementia, as demonstrated in the clinical trials. Kisunla marks […]

Guidelines + Trials Rundown: RSV Immunization in Adults

RSV Immunization in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on respiratory syncytial virus (RSV) immunization in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for RSV vaccinations, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject […]

Guidelines + Trials Rundown Multiple Myeloma

Multiple Myeloma in Adults – Guidelines+ Trials Rundown

In the latest edition of our Guidelines+ Trials Rundown Series, we delve into the most recent research and clinical trials focusing on multiple myeloma (MM) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for MM, specifically targeting adults in the United States. Please note that the dates […]

Guidelines+ Trials Spotlight - Hidradenitis Suppurativa

Hidradenitis Suppurativa in Adults – Guidelines+ Trials Rundown

Today, we will be looking into the latest research and clinical trials focused on hidradenitis suppurativa (HS) in adults. The following list has been carefully curated by evaluating the ongoing Phase 3 trials for HS, specifically targeting adults in the United States. Please note that the dates provided are approximate and subject to change. This […]

Guidelines+ Trials Spotlight - Soft Tissue Sarcoma

Soft Tissue Sarcoma – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to soft tissue sarcomas in adults. The below list was curated by assessing the ongoing Phase 3 trials for soft tissue sarcomas, specific to adults, and based in the United States. The dates provided are estimates, and subject to change. The list […]

Guidelines+ Trials Spotlight - Hemochromatosis

Advances in Hemochromatosis – Guidelines+ Trials Rundown

Today, we will explore the latest research and clinical trials focused on the management of hemochromatosis. The following list has been carefully curated by evaluating ongoing trials related to hemochromatosis in the United States. Please note that the dates provided are approximate and may be subject to change. The list primarily includes studies with results […]

Guidelines + Trials Rundown - Juvenile Arthritis

Advances in Juvenile Arthritis – Guidelines+ Trials Rundown

We’re going to take a look at the ongoing studies and clinical trials specific to juvenile arthritis. The below list was curated by assessing the ongoing Phase 3 trials for juvenile arthritis that are based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that have […]

Guidelines+ Trials Spotlight - Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA

Imfinzi® Muscle-Invasive Bladder Cancer Trial Results NIAGARA – Guidelines+ Trials Spotlight

According to the American Cancer Society, bladder cancer accounts for approximately 4% of all cancers in the United States, making it the fourth most common cancer in men and less common in women. The likelihood of men developing bladder cancer in their lifetime is about 1 in 28, while for women, the chance is about […]

Guidelines+ Trials Rundown - Gout

Gout in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to gout in adults. The below list was curated by assessing the ongoing Phase 3 trials for gout, specific for adults, and based in the United States. The dates provided are estimates, and subject to change. The list is primarily studies that […]

Guidelines+ Trials Spotlight - Produce

Food is Medicine & Produce Prescriptions – Guidelines+ Trials Spotlight

Nutrition plays a crucial role in maintaining overall health and well-being. A study from The Lancet revealed that poor diet is responsible for one in five deaths globally, contributing to a variety of chronic diseases such as cardiovascular diseases, cancer, and type 2 diabetes. Unfortunately, individuals with lower incomes, those residing in rural areas, and […]

Guidelines+ Trials Rundown - Celiac Disease

Celiac Disease in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to celiac disease in adults. The following list has been curated by evaluating the current Phase 2 and 3 clinical trials for celiac disease in adults conducted in the United States. Please note that the dates provided are approximate and may be […]

Guidelines + Trials Migraine Prevention

Migraine Prevention in Adults – Guidelines+ Trials Rundown

Today we’re going to cover the second article in a two part series that takes a look at the ongoing studies and clinical trials specific to management of migraine in adults, including acute migraine treatment and migraine prevention (both chronic migraine prevention and episodic migraine prevention).  The focus of Part 1 was Acute Migraine Treatment […]

Guidelines + Trials Spotlight - Enhertu Metastatic Breast Cancer

Enhertu® Metastatic Breast Cancer Trial Results DESTINY-Breast06

According to the National Institutes of Health (NIH), around 13% of women will receive a cancer diagnosis at some stage in their lives. In 2021, an estimated 3,972,256 women were living with cancer in the United States. The most prevalent cancer subtype is HR+/HER2-, with an age-adjusted rate of 90 new cases per 100,000 women, […]

Acute Migraine Guidelines + Trials Rundown

Acute Migraine Treatment in Adults – Guidelines+ Trials Rundown

Today we’re going to cover the first article in a two-part series that takes a look at the ongoing studies and clinical trials specific to management of migraine in adults, including acute migraine treatment and migraine prevention (both chronic migraine prevention and episodic migraine prevention).  For Part 1 we’ll be starting with Acute Migraine Treatment […]

Guidelines+ Trials Rundown Schizophrenia in Adults

Schizophrenia in Adults – Guidelines+ Trials Rundown

Today we’re going to look at the ongoing studies and clinical trials specific to management of schizophrenia in adults, including in acutely psychotic people with schizophrenia and relapse prevention. The below list was curated by assessing the ongoing Phase 3 trials for migraine treatments, specific for adults, and based in the United States. The dates […]